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Eruzioni cutanee

There are many different types of skin rashes and many different causes of skin rashes. Although most skin rashes are harmless, some do need treatment (which may be tablets, creams or ointments) from your doctor or pharmacist.

Some rashes (especially dark red or purple rashes that don't fade when you press them) may even need urgent medical treatment as they can be associated with meningitis and blood infection (septicaemia).

At a glance

  • Rashes can be described by their appearance, such as redness or flat spots.

  • Macules are flat, abnormally coloured skin areas, while papules and nodules are solid raised areas.

  • Blisters are fluid-filled swellings, with vesicles being small and bullae larger.

  • Purpura are reddish-purple lesions that do not fade with pressure.

  • Common causes of rashes include infections, allergic reactions, and skin conditions like eczema or psoriasis.

  • See a doctor urgently if a rash doesn't fade with pressure, you feel unwell, or are concerned.

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This leaflet is a guide but if you have any concerns, you must seek urgent clinical assessment if:

  • The rash doesn't quickly disappear.

  • You feel unwell.

  • The rash does not fade with pressure (the best way to test this is to press a glass gently against the rash to see if it fades).

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How are skin rashes described?

Skin rashes can be described in the following way:

  • Redness of the skin (called eritema).

  • Flat abnormally coloured areas of skin (called macules). Macules are often either red, dark red or purple, brown or white.

  • Solid raised areas which are up to half a centimetre across (called papules).

  • Solid raised areas which are more than half a centimetre across (called nodules).

  • Areas of red raised skin (called plaques) e scales, which have a flaky silvery-white appearance.

  • Reddish-purple lesions which do not fade with pressure (called porpora):

    • If less than one centimetre across then these are called petechiae.

    • If more than one centimetre across then they are called ecchymoses.

  • Blisters: these are swellings of the skin containing fluid:

    • If a blister is less than half a centimetre across then it is called a vesicle. If filled with yellow fluid (pus) then it is called a pustule.

    • If a blister is larger than half a centimetre across it is called a bulla (plural is bullae).

Skin disorders that can cause itching include (please click the links to separate leaflets which provide further information):

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Please click the links to separate leaflets which provide further information:

Red (erythema) but not scaly skin rash

Red (erythema) and scaly skin rash

Macules

  • Red macules may be due to a reaction to a medicine or a eruzione cutanea virale - such as morbillo oppure rosolia - as well as other causes.

  • A brown macule may be a mole but check with your doctor if a mole changes or you are concerned it might be a melanoma.

  • A white macule may be due to a condition which causes pale patches of skin (called vitiligine) or a skin complaint with flaky discoloured areas (called pityriasis versicolor).

  • If a macule is dark red or purple and does not fade when you put pressure on it then it is a purpura (see below) and you need to see a doctor urgently. This is because it could be a sign of meningite or blood infection (setticemia).

Papules

Purpura and petechiae

  • These are dark red or purple and don't fade when you press them. You need to see a doctor urgently because there may be a serious cause that needs urgent treatment, such as meningococcal infection.

  • However, common causes include injury to the skin or repeated coughing. More serious common causes include liver disease such as cirrosi.

  • Less common causes include vasculitis (eg, Porpora di Henoch-Schönlein) or a low level of platelets in your blood (eg, porpora trombotica trombocitopenica).

Vasculite

Vasculite

Nodules

Blisters

Pustules

  • Skin infection by a virus (eg, herpes labiale due to herpes simplex virus) or bacterial germs (impetigine).

  • Inflammation - eg psoriasi.

  • Pustular skin reaction to medicine you are taking.

  • Pustules on your face may be acne or rosacea.

Ulcere

Ulcers may be due to venous leg ulcers, ulcere da pressione, diabetes skin ulcers oppure cancerous (malignant) skin ulcers.

This leaflet is a guide but if you have any concerns, you must telephone or see your GP, especially if:

  • The rash doesn't quickly disappear.

  • You feel unwell.

  • The rash does not fade with pressure (the best way to test this is to press a glass gently against the rash to see if it fades).

  • You are not sure what has caused the rash or have any other concerns.

Domande frequenti

What does it mean if a rash doesn't fade when I press on it?

If a rash, particularly if it's dark red or purple, does not fade when you apply pressure (e.g., with a glass), it's called purpura. This needs urgent medical attention as it can be a sign of serious conditions like meningitis or a blood infection. Common causes also include injury or repeated coughing, but less commonly it could be due to vasculitis or a low level of platelets.

Can certain medications cause a skin rash?

Yes, a skin rash can be a reaction to a medicine you are taking. This can manifest as red (erythema) but not scaly skin, or even lead to blisters or pustules as a reaction.

What are some common reasons for red, scaly skin rashes?

Red and scaly skin rashes can be caused by conditions such as psoriasis, eczema (sometimes called dermatitis), seborrhoeic dermatitis (known as cradle cap in babies), fungal skin infections (like athlete's foot or ringworm), pityriasis rosea, pityriasis versicolor, lupus erythematosus, and lichen planus.

Are all moles considered a type of macule?

A brown macule may indeed be a mole. However, it's important to check with your doctor if a mole changes in appearance or if you are concerned it might be a melanoma, which is a type of skin cancer.

What causes blisters on the skin?

Blisters can be caused by skin inflammation, including reactions to medicines, contact dermatitis, or eczema (like varicose eczema on the legs). They can also result from diseases of your immune system, viral infections such as chickenpox, hand, foot and mouth disease, or skin infections like impetigo or herpes simplex (cold sores/genital herpes) or herpes zoster (shingles). Rarer causes include pemphigus and pemphigoid.

Ulteriori letture e riferimenti

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About the authorView full bio

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Dr Hayley Willacy, FRCGP

Medico di base, Autore medico

MBChB (1992), DRCOG, DFFP, MRCOG (Part 1) MRCGP (2007), DFSRH (2013), MSc - medical education (2020)

Dr Hayley Willacy was an NHS GP working in northwest England, who retired from clinical practice in 2022 after 30 years. 

About the reviewerView full bio

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Dr Colin Tidy, MRCGP

Medico di base, Autore medico

MBBS, MRCGP, MRCP (Paediatrics), DCH

Dr Colin Tidy is an NHS Doctor, based in Oxfordshire.

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