Malassorbimento gastrointestinale

What are the symptoms of gastrointestinal malabsorption?

There may be no symptoms if the malabsorption is mild and has not continued for very long. More severe or persistent malabsorption may lead to:

Stanchezza (affaticamento)

This is because of a lack of energy as you are not absorbing nutrients and essential vitamins and minerals from food.

Perdita di peso

If you can't absorb enough energy (calories) from your food then this will cause you to lose weight (and may cause poor growth in children).

Diarrrea persistente (cronica)

This is a common symptom of persistent malabsorption.

Pale, bulky and smelly stools (steatorrhoea)

This is because there is excessive fat in the stools and they become pale, bulky and very smelly. Fatty stools float and are difficult to flush away. They often leave a greasy rim around the pan.

Intestinal malabsorption may also cause:

• Carenza di ferro e anemia da carenza di ferro.

• Carenza di folati.

• Carenza di vitamina B12.

• Abnormal bleeding, caused by low vitamin K.

• Vitamin D deficiency including rickets and osteomalacia.

• Edema, which occurs because of insufficient protein and calories absorbed into the body.

There may also be other symptoms due to the particular underlying condition that is causing the malabsorption.

What are the causes of gastrointestinal malabsorption?

The most common causes in the UK are celiachia, morbo di Crohn and chronic pancreatitis. However, the malabsorption of simple carbohydrates affects about 1 in 4 people in Europe. Some diseases associated with malabsorption are found more often in some families - for example, coeliac disease, Crohn's disease, fibrosi cistica and lactose intolerance.

The causes of gastrointestinal malabsorption include:

Problems with absorbing food from the gut (bowel) into your body

• Malattia celiaca - a long-term disease that mostly affects the small intestine.

• Intolleranza al lattosio.

• Allergia alle proteine del latte vaccino.

• Soya milk intolerance.

• Fructose intolerance.

• Infection - for example, tubercolosi intestinale, diarrea del viaggiatore.

• Immune deficiency - for example, infezione da HIV.

• Pancreatic insufficiency - for example, fibrosi cistica, chronic pancreatitis, cancro al pancreas.

• Bile salts and acid malabsorption.

Structural causes

Malabsorption may be cause by loss of part of the bowel that is essential to absorb the broken down (digested) food into the body - for example:

• Removal of the stomach or part of the bowel after a stomach or bowel operation.

• morbo di Crohn.

Causes outside the bowel

Esempi includono:

• Un ghiandola tiroidea iperattiva (ipertiroidismo).

• Eating disorders: anoressia nervosa, bulimia nervosa.

Quali test sono necessari?

Initial tests will include esami del sangue e stool tests. Further tests may include an abdominal ecografia, barium studies and a tomografia computerizzata (TC) o un risonanza magnetica (RM). Any further tests will depend on the likely underlying cause of the intestinal malabsorption.

What are the treatments for gastrointestinal malabsorption?

The treatment will mainly depend on the underlying cause of the malabsorption. However, treatment will also be needed to increase the amount of essential nutrients in the body, including carbohydrates, proteins, fats, minerals and fat-soluble vitamins (nutritional support).