How the urinary tract works

Urine is made by your two kidneys, one on each side of the tummy (abdomen). Urine drains down tubes called ureters into the bladder. There it is stored and passed out through a tube called the urethra, when you go to the toilet.

Diagramma della vista laterale dei genitali maschili e del taglio trasversale delle vie urinarie

Most urine infections are caused by germs (bacteria) that come from your own bowel. They cause no harm in your bowel but can cause infection if they get into other parts of your body. Some bacteria lie around your back passage (anus) after you pass a stool. These bacteria sometimes travel up the tube called the urethra and into your bladder. Some bacteria thrive in urine and multiply quickly to cause infection.

A urine infection is often called a urinary tract infection (UTI) by healthcare professionals. When the infection is just in the bladder and urethra, this is called a lower UTI. If it travels up to affect one or both kidneys as well then it is called an upper UTI. This can be more serious than lower UTIs, as the kidneys can be damaged by the infection.

In many cases the infection occurs for no apparent reason. There is no problem with the bladder, kidney, prostate gland, or defence (immune) system that can be identified. In other cases, an underlying problem can increase the risk of developing a urine infection.

Urinary tract infection in older women

• After the menopausa the lining of tissues around your genital area may become more fragile. This is called vaginite atrofica, or genitourinary syndrome of the menopause. It is associated with having more urine infections.

• A prolapse of the womb (uterus) or vagina can also increase your risk of infection.

In older men

Un ipertrofia prostatica may stop the bladder from emptying properly. Some urine may then pool in the bladder. Germs (bacteria) are more likely to multiply and cause infection in a stagnant pool of urine.

In both

• Bladder or kidney problems may lead to infections being more likely. For example, calcoli renali or conditions that cause urine to pool and not drain properly.

• Having a thin, flexible, hollow tube (called a catheter) in place to drain urine.

• An underlying health condition may also be responsible. A poor immune system increases the risk of having any infection, including urine infections. For example, if you are having chemioterapia to treat cancer. Diabetes can also increase your risk of having urine infections.

• Being costipato. If your lower gut (bowel) is full and swollen, it may press on the bladder. This may stop it emptying properly, making you more prone to urine infection.

Infection in the bladder (cystitis):

• Pain when you pass urine.

• You pass urine more frequently.

• You may have pain in your lower tummy (abdomen).

• Your urine may become cloudy, bloody or offensive-smelling.

• You may have a high temperature (fever).

Infection in the kidneys:

• It may cause you to feel generally unwell.

• There may be a pain in your back; this is usually around the side of the back (the loin), where each kidney is located.

• You may have a high fever, which might feel like a chill or make you shake. You may feel sick, or be sick (vomit).

The confusion is caused by a combination of factors such as having a fever and having a lack of fluid in the body (dehydration). The confusion should pass when the infection has been treated. An infection which is left untreated can lead to sepsis, which can be very serious, or to long-term kidney damage.

• A course of an medicinale antibiotico will usually clear the infection quickly. You should see a doctor if your symptoms are not gone, or nearly gone, after a few days.

• Paracetamolo oppure ibuprofene di solito allevia qualsiasi dolore, disagio o febbre alta.

• An underlying cause such as an ipertrofia prostatica oppure stipsi may be found and need treatment.

• It is helpful to drink plenty of water.

How common are urine infections?

Urine infections are much more common in women than in men. This is because in women the urethra - the tube from the bladder that passes out urine - is shorter. Also it opens nearer the back passage (anus) than in men. Half of all women will have a urine infection that needs treating in their lifetime.

Urine infections are less common in men. They are very uncommon in young and middle-aged men. They are more common in older men. Men who have to use a urinary catheter are at higher risk of a UTI. A catheter is a thin, flexible, hollow tube used to drain urine. Older men are more likely to need a catheter because of prostate problems, which become more common with age.

Urine infections tend to become more common as you get older.

Sono necessari dei test?

In some cases the diagnosis may be obvious and no tests are needed. For a woman who is aged under 65 and is not pregnant, it would be reasonable for a GP to provide antibiotics on the basis of a phone call with appropriate symptoms, though this might not be done if it was a second UTI in a short period of time. A test on a campione di urina is sometimes used to confirm the diagnosis and identify what germ (bacterium) is causing the infection. Sometimes a dipstick test can provide enough information immediately. In other cases the urine sample is sent to a laboratory for further examination under a microscope. This result takes several days.

Further tests are not usually necessary if you are otherwise well and have a one-off infection. However, your doctor may advise tests of your kidney or bladder if an underlying problem is suspected.

An underlying problem is more likely if the infection does not clear with antibiotic medication, or if you have:

• Symptoms that suggest a kidney is infected (and not just the bladder).

• Recurring urine infections (for example, two or more episodes in a three-month period).

• Had problems with your kidney in the past, such as kidney stones or a damaged kidney.

• Symptoms that suggest a blockage (an obstruction) to the flow of urine.

Relevant tests may include:

• A blood test.

• A scan of your kidneys or bladder, such as an ecografia.

• Tests to see how well your bladder is functioning, called urodynamic tests.

• A look inside your bladder with a special telescope (cystoscopy).

Qual è la prospettiva (prognosi)?

Most people improve within a few days of starting treatment. See a doctor if you do not quickly improve. If your symptoms do not improve despite taking an antibiotic medicine then you may need an alternative antibiotic. This is because some bacteria are resistant to some types of antibiotics. This can be identified from tests done on your urine sample.

Can I prevent urine infections?

There are some measures which may help in some cases:

• It makes sense to avoid constipation, by eating plenty of fibre (such as fruit) and drinking enough fluid.

• Older women with vaginite atrofica may wish to consider hormone replacement creams or pessaries. These have been shown to help prevent urine infections.

• If there is an underlying medical problem, treatment for this may stop urine infections occurring.

• For some people with repeated urine infections, a preventative low dose of antibiotic taken continuously may be prescribed.

• Women should wipe themselves from front to back after opening their bowels, to avoid getting germs (bacteria) from the bowel into the bladder.