Ibuprofene per il dolore e l'infiammazione
Brufen, Calprofen, Nurofen
Revisione paritaria di Dr Colin Tidy, MRCGPUltimo aggiornamento di Michael Stewart, MRPharmSUltimo aggiornamento 27 Feb 2023
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Ibuprofen is a painkiller that eases pain and reduces inflammation. It should be taken with a meal or a snack.
The most common side effects are stomach ache, indigestion, feeling sick (nausea), and being sick (vomiting).
Ibuprofen is not recommended for children who have chickenpox. Use paracetamol instead.
Speak with a doctor before taking ibuprofen if you have ever had a bad reaction to any other anti-inflammatory painkiller.
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About ibuprofen
Tipo di medicinale | Un farmaco antinfiammatorio non steroideo (FANS) |
Utilizzato per | Relief of pain, inflammation, or fever |
Chiamato anche (UK) | Anadin®, Brufen®; Calprofen®; Cuprofen®; Fenpaed®; Feminax®; Flarin®; Ibucalm®; Noubid®; Nurofen® |
Chiamato anche (USA) | Advil®; Alivio®; Aprofen®; Cedaprin®; CounterAct® IB; Dolex®; Dragon Tabs®; Flex-Prin®; Ibutab®; Motrin® IB; Probufen®; Profen® IB; Proprinal® |
Disponibile come | Tablets, capsules, effervescent granules, oral liquid medicine, modified-release tablets, orodispersible (melt in the mouth) tablets, chewable capsules |
What is ibuprofen used for?
Torna ai contenutiIbuprofen is a type of anti-inflammatory painkiller (also called non-steroidal anti-inflammatory drugs (NSAIDs), or 'anti-inflammatories') that is used to treat pain and reduce inflammation (swelling).
Conditions that it is commonly used to treat include:
Dental pain.
Pain after surgical operations.
Ibuprofen can also be used to relieve cold and 'flu-like' symptoms including alta temperatura (febbre). It can be taken by adults and by children over the age of 3 months.
Ibuprofen is available on prescription, and you can also buy a number of preparations which contain ibuprofen without a prescription at pharmacies and other retail outlets.
It is also available as a gel which can be applied directly to your skin to help relieve muscle and joint pain.
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How does ibuprofen work?
Torna ai contenutiIbuprofen works by blocking the effect of natural chemicals called cyclo-oxygenase (COX) enzymes.
These enzymes help to make other chemicals in the body, called prostaglandins. Some prostaglandins are produced at sites of injury or damage, and cause pain and inflammation.
By blocking the effect of COX enzymes, fewer prostaglandins are produced, which means pain and inflammation are eased.
Side effects of ibuprofen
Torna ai contenutiCommon side effects of ibuprofen are:
Indigestione.
Bruciore di stomaco.
Dolore allo stomaco.
Sensazione di nausea.
Vomito.
Diarrea.
You will find a full list of the side effects associated with ibuprofen from the manufacturer's printed information leaflet supplied with the medicine.
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How to manage ibuprofen side effects
Torna ai contenutiGli effetti indesiderati spesso migliorano man mano che il tuo corpo si adatta al nuovo medicinale, ma parla con il tuo medico o farmacista se uno dei seguenti persiste o diventa problematico.
Common ibuprofen side effects | Cosa posso fare se sperimento questo? |
Indigestion, heartburn, stomach pain | Remember to take your doses with food, or with a glass of milk. If the discomfort continues, speak with your doctor |
Sentirsi male o vomitare, diarrea | Stick to simple meals. Drink plenty of liquid to replace any lost fluids |
Importante: if you experience any of the following less frequent but possibly serious symptoms, stop taking ibuprofen and contact your doctor for advice straightaway:
Se hai difficoltà respiratorie come respiro sibilante o mancanza di respiro.
If you have any signs of an allergic reaction such as swelling around your mouth or face, or an itchy skin rash.
If you pass blood or black stools, bring up (vomit) blood, or have severe stomach pains.
Ibuprofen may increase the risk of developing serious skin infections when used in children with chickenpox. Therefore, paracetamol is usually recommended in chickenpox and ibuprofen should not be used.
Ibuprofen does not affect your ability to drive or to use machinery.
Se si verificano altri sintomi che ritieni possano essere dovuti al medicinale, parla con il tuo medico o farmacista per ulteriori consigli.
Who should not take ibuprofen?
Torna ai contenutiSome medicines are not suitable for people with certain conditions. Before taking ibuprofen it is important that your doctor knows:
If you have ever had a stomach or duodenal ulcer, or if you have an inflammatory bowel disorder such as morbo di Crohn oppure colite ulcerosa.
If you have asma or any other allergic disorder.
Se sei incinta, stai cercando di avere un bambino o stai allattando.
Se hai problemi con il funzionamento del tuo fegato, o se hai problemi con il funzionamento dei tuoi reni.
Se hai una condizione cardiaca o un problema con i tuoi vasi sanguigni o la circolazione.
If you have ipertensione.
Se hai problemi di coagulazione del sangue.
Se hai livelli elevati di zucchero nel sangue o di colesterolo.
Se hai un disturbo del tessuto connettivo come il lupus eritematoso sistemico. Questa è una condizione infiammatoria che è anche chiamata lupus o LES.
Se stai assumendo altri medicinali. Questo include qualsiasi medicinale che stai assumendo e che è disponibile per l'acquisto senza prescrizione medica, così come i medicinali a base di erbe e complementari.
If you have ever had an allergic reaction to any other NSAID (such as aspirina, naprossene, diclofenac, and indometacina), or to any other medicine.
How to take ibuprofen
Torna ai contenutiBefore you take ibuprofen, read the leaflet in the pack. It explains how the medicine works and lists possible side effects.
For adults and children 12 and older, the usual dose is 200-400 mg three or four times a day if needed. If your tablets are the slow-release kind, the dose is different - they’re usually taken once or twice a day.
Different brands may have different strengths, so always check the label to make sure you’re taking the right amount
If you’re giving liquid ibuprofen to a child, the dose depends on their age. Read the bottle label carefully so you give the correct amount. The doses below are a general guide for a 100 mg/5 ml ibuprofen suspension.
3-5 months: 50 mg (2.5 ml) three times daily.
6-11 months: 50 mg (2.5 ml) three or four times daily.
1-3 years: 100 mg (5 ml) three times daily.
4-6 years: 150 mg (7.5 ml) three times daily.
7-9 years: 200 mg (10 ml) three times daily.
10-11 years: 300 mg (15 ml) three times daily.
Ibuprofen is best taken with food. This will help to protect your stomach from side effects such as indigestione.
If you have been prescribed a modified-release form of ibuprofen (Brufen Retard® brand), swallow the tablet or capsule whole with a glass of water. Do not crush or break the tablets.
If you have been prescribed a sachet containing ibuprofen granules (Brufen® Effervescent Granules), mix the contents of the sachet into a glass of water to make a fizzy drink. Drink it straightaway after mixing it.
If you forget a dose, take it when you remember - unless it’s almost time for your next one. If it is, just skip the missed dose and take the next one as normal. Do not take two doses at once.
Ottenere il massimo dal tuo trattamento
Torna ai contenutiYour doctor will give you the lowest dose of ibuprofen for the shortest time to help avoid side effects. If you need it long-term, they might also give you another medicine to protect your stomach.
If you bought ibuprofen yourself, only use it for a short time and stop once the pain or fever goes away.
Keep your regular check-ups with your doctor, especially if you're taking ibuprofen for a long-term problem.
If you have asthma, ibuprofen can sometimes make symptoms like wheezing or breathlessness worse. If that happens, stop taking it and see your doctor.
Some anti-inflammatory medicines, including ibuprofen, may slightly increase the risk of heart and blood vessel problems if used long-term. If you’re worried, talk to a healthcare professional. Always stick to the recommended dose.
If you buy other medicines, check with a pharmacist that they’re safe to take with ibuprofen. Don’t take ibuprofen along with any other anti-inflammatory painkillers - some cold and flu medicines contain them.
Se devi sottoporti a un'operazione o a un trattamento dentistico, informa la persona che esegue il trattamento sui medicinali che stai assumendo.
How to store ibuprofen
Torna ai contenutiTenere tutti i medicinali fuori dalla portata e dalla vista dei bambini.
Conservare in un luogo fresco e asciutto, lontano da fonti di calore e luce diretta.
Informazioni importanti su tutti i medicinali
Torna ai contenutiInformazioni importanti su tutti i medicinali
Non assumere mai più della dose prescritta. Se sospetti che tu o qualcun altro possa aver assunto un sovradosaggio di questo medicinale, recati al pronto soccorso del tuo ospedale locale. Porta con te il contenitore, anche se è vuoto.
Non conservare medicinali scaduti o indesiderati. Portali alla tua farmacia locale che li smaltirà per te.
Se hai domande su questo medicinale, chiedi al tuo farmacista.
Segnala effetti collaterali di un medicinale o vaccino
Se si verificano effetti collaterali, è possibile segnalarli online tramite il Yellow Card website.
Domande frequenti
Torna ai contenutiHow long does it take for ibuprofen to work?
Ibuprofen usually starts working within 20 to 30 minutes, with its full pain-relieving and anti-inflammatory effects typically felt after about 1 to 2 hours. How quickly it works can depend on your metabolism and the type of ibuprofen.
Can you take ibuprofen while pregnant?
You should avoid taking ibuprofen while pregnant, especially after 20 weeks, as it may affect the baby’s development and increase the risk of complications in later pregnancy.
Can you drink alcohol with ibuprofen?
It’s generally best to avoid alcohol while taking ibuprofen as it can increase the risk of stomach irritation, bleeding, and other side effects. However, drinking a small amount of alcohol is usually fine.
Can you take ibuprofen and paracetamol together?
Yes, ibuprofen and paracetamol can be taken together for short-term pain relief as they work differently in the body. They can also be taken alternately to maintain consistent relief.
Can you take ibuprofen with co-codamol?
Yes, you can take ibuprofen with co-codamol as they work differently to relieve pain. They can provide stronger pain control when used together. Always follow dosing instructions carefully.
How long does ibuprofen last?
The effects of ibuprofen typically last 4 to 6 hours, depending on the dose and formulation. Extended-release versions may last longer.

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Ulteriori letture e riferimenti
- Manufacturer's PIL, Ibuprofen 200 mg and 400 mg film-coated tablets (PL 16363/0523); Aurobindo Pharma - Milpharm Ltd, Il Compendio Elettronico dei Medicinali. Datato giugno 2020.
- Manufacturer's PIL, Ibuprofen 100 mg/5 ml Oral Suspension; Pinewood Healthcare Ltd, The electronic Medicines Compendium. Dated February 2023.
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Storia dell'articolo
Le informazioni su questa pagina sono scritte e revisionate da clinici qualificati.
Prossima revisione prevista: 8 Ago 2027
27 Feb 2023 | Ultima versione

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