Compresse di metilprednisolone
Medrone
Revisione paritaria di Sid DajaniUltimo aggiornamento di Michael Stewart, MRPharmSUltimo aggiornamento 21 Set 2022
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Methylprednisolone belongs to a class of medicines known as corticosteroids (more commonly called steroids).
Il tuo farmacista ti darà una 'Scheda di Trattamento con Steroidi' blu. Portala sempre con te.
Take methylprednisolone tablets with food.
If you need any medical treatment, make sure the person treating you knows you are taking methylprednisolone. This is because your dose may need to be increased for a short while.
A colpo d'occhio
Methylprednisolone is a corticosteroid medicine used to treat many allergic and inflammatory conditions.
It works by interfering with chemicals in your body that cause inflammation.
Take your tablets once daily with food, usually at breakfast time.
Do not stop taking methylprednisolone suddenly; your doctor will need to reduce your dose gradually.
Carry a Steroid Treatment Card if your course of treatment lasts more than three weeks.
See your doctor straight away if you become ill or think you have been in contact with chickenpox, measles, or shingles.
About methylprednisolone
Tipo di medicinale | A corticosteroid medicine |
Utilizzato per | Allergic and inflammatory conditions |
Chiamato anche | Medrone®; Depo-Medrone®; Solu-Medrone® |
Disponibile come | Compresse e iniezione |
Methylprednisolone tablets belong to a group of medicines called corticosteroids. It is sometimes referred to simply as an oral steroid. Steroidi orali are used to treat a wide variety of conditions. Some examples include inflammatory bowel diseases (for example, morbo di Crohn, colite ulcerosa), autoimmune diseases (for example, lupus eritematoso sistemico (LES), sarcoidosi), joint and muscle diseases (for example, artrite reumatoide), and allergie. They are also used to treat some cancers.
Methylprednisolone works in part by interfering with the release of certain chemicals in your body which cause inflammation.
Methylprednisolone is also available in the form of an injection. Some types of injection are used when treatment is needed quickly, or a person is unable to swallow tablets. Other types of injection are given to relieve inflammation in a specific area, such as a painful or swollen joint. This leaflet gives advice for people taking methylprednisolone tablets.
Before taking methylprednisolone
Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking methylprednisolone it is important that your doctor knows:
Se hai la pressione alta (ipertensione).
Se hai avuto un infarto o se hai altri problemi cardiaci.
Se hai problemi con il funzionamento del tuo fegato, o se hai problemi con il funzionamento dei tuoi reni.
If you (or a close family member) have either diabetes or an eye condition called glaucoma.
If you have any of the following conditions: an underactive thyroid, 'thinning' of the bones (osteoporosis), epilepsy, a condition causing muscle weakness (called myasthenia gravis), a stomach ulcer, or a bowel disorder.
Se hai mai avuto un problema di salute mentale.
If you are pregnant or breastfeeding. (Oral steroids like methylprednisolone can be taken while you are expecting or breastfeeding; however, it is important that your doctor knows about the baby.)
If you have any kind of infection at the moment, or if you have ever had tuberculosis (TB).
If you have ever had an unwanted blood clot in an artery or a vein.
Se hai recentemente ricevuto, o stai per ricevere, qualsiasi vaccinazione.
If you are taking other medicines. This includes any medicines which are available to buy without a prescription, as well as herbal and complementary medicines.
Se hai mai avuto una reazione allergica a un medicinale, o se hai mai sviluppato dolori muscolari dopo aver assunto un medicinale steroideo.
How to take methylprednisolone tablets
Before starting the treatment, read the manufacturer's printed information leaflet from inside the pack and any additional information you are given by your doctor. These will give you more information about methylprednisolone and will also provide you with a full list of side-effects which you could experience from taking it.
Your doctor or pharmacist will tell you how many tablets to take for each dose. It is usual to take methylprednisolone once daily at breakfast-time. If you have been told otherwise, you must take the tablets exactly as you have been told by your doctor.
Take methylprednisolone with food. Swallow the tablet with a drink of water.
If you forget to take a dose at your usual time, take it as soon as you remember (with something to eat). If you do not remember until the following day, leave out the missed dose. Do not take two doses together to make up for a forgotten dose.
Continue to take methylprednisolone until your doctor tells you to stop. Stopping taking the tablets suddenly can cause problems so your doctor will want you to reduce your dose gradually over a period of time if/when this becomes necessary.
Ottenere il massimo dal tuo trattamento
If your course of treatment is due to last more than three weeks, you will be given a 'Steroid Treatment Card' which says that you are on steroids and contains some important advice for you. It is important that you read this card and carry it with you at all times. It also contains details about your dose, how long you have been taking methylprednisolone for, and who prescribed it for you. Please make sure that this information is kept up to date. If you are having an operation or dental treatment or any treatment for an injury, tell the person carrying out the treatment that you are taking methylprednisolone and show them your treatment card. This is because your dose may need adjusting.
Cerca di mantenere i tuoi appuntamenti regolari con il tuo medico. Questo è per permettere al tuo medico di controllare i tuoi progressi. Il tuo medico vorrà che tu faccia esami di tanto in tanto per assicurarsi che tu rimanga libero da alcuni degli effetti collaterali indesiderati del trattamento.
There are several strengths of methylprednisolone tablets available: 2 mg, 4 mg, 16 mg, and 100 mg. Each time you collect a new supply of tablets from your pharmacy, check to see if the tablets are the same as before. If they are different, speak with your pharmacist who will check it out for you.
Methylprednisolone can suppress your immune system, so it is important if you become ill that you make an appointment to see your doctor straightaway. Also, if you come into contact with anyone who has measles, shingles or chickenpox (or anyone who suspects they might have them), you must see your doctor as soon as possible.
Some vaccines are not suitable for you while you are being treated with methylprednisolone. If you need any immunisations, make sure you mention that you are taking an oral steroid.
It is best not to drink grapefruit juice while you are on methylprednisolone. This is because a chemical in grapefruit juice is thought to increase the amount of methylprednisolone in your bloodstream, and could make side-effects more likely.
If you buy any medicines, check with your pharmacist that they are suitable to take with methylprednisolone.
Can methylprednisolone cause problems?
Along with its useful effects, methylprednisolone can cause unwanted side-effects which your doctor will discuss with you. The benefits of taking an oral steroid usually outweigh the side-effects; however, they can sometimes be troublesome. The table below contains some of the most common ones associated with methylprednisolone. The best place to find a full list of the side-effects which can be associated with your medicine, is from the manufacturer's printed information leaflet supplied with the medicine. Alternatively, you can find an example of a manufacturer's information leaflet in the reference section below.
Although not everyone experiences side-effects, and some will improve as your body adjusts to the new medicine, speak with your doctor or pharmacist if you become concerned about any of the following:
Common methylprednisolone side-effects | Cosa posso fare se sperimento questo? |
Tummy (abdominal) pain, indigestion, feeling sick (nausea) | Stick to simple foods. If you are sick (vomit) and there is blood present, you must speak with your doctor straightaway |
Muscle weakness or feeling tired | Non guidare e non utilizzare strumenti o macchinari mentre sei sotto effetto |
Mood or behavioural changes, especially at the beginning of treatment | If you become confused, irritable or start having worrying thoughts about harming yourself, speak with your doctor straightaway |
Difficulties sleeping, headache, increased weight, and irregular periods in women | Se uno di questi diventa problematico, parla con il tuo medico |
Increased risk of getting an infection | If you become ill, make an appointment to see your doctor straightaway |
Long-term treatment with methylprednisolone may cause other unwanted effects | If you have any symptoms which are causing you concern, you should arrange to see your doctor for advice |
Importante: you should let your doctor know if you start to experience blurred vision or other vision problems whilst taking methylprednisolone.
For more information about side-effects which are possible when methylprednisolone is taken long-term, see the separate leaflet called Steroidi Orali.
How to store methylprednisolone tablets
Tenere tutti i medicinali fuori dalla portata e dalla vista dei bambini.
Conservare in un luogo fresco e asciutto, lontano da fonti di calore e luce diretta.
Informazioni importanti su tutti i medicinali
Informazioni importanti su tutti i medicinali
Non assumere mai più della dose prescritta. Se sospetti che tu o qualcun altro possa aver assunto un sovradosaggio di questo medicinale, recati al pronto soccorso del tuo ospedale locale. Porta con te il contenitore, anche se è vuoto.
Questo medicinale è per te. Non darlo mai ad altre persone, anche se la loro condizione sembra essere la stessa della tua.
Non conservare medicinali scaduti o indesiderati. Portali alla tua farmacia locale che li smaltirà per te.
Se hai domande su questo medicinale, chiedi al tuo farmacista.
Segnala effetti collaterali di un medicinale o vaccino
Se si verificano effetti collaterali, è possibile segnalarli online tramite il Sito web Yellow Card.

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Domande frequenti
Can I take all my methylprednisolone tablets at once in the morning?
Yes, it is common to take methylprednisolone once daily at breakfast-time. However, you should always follow the specific instructions given by your doctor regarding how many tablets to take for each dose and when to take them.
Why would my doctor prescribe methylprednisolone given the potential side-effects?
Methylprednisolone is prescribed to treat a wide range of conditions, including various allergic reactions and inflammatory diseases. Your doctor will have discussed the potential side-effects with you, and generally, the benefits of taking an oral steroid like methylprednisolone are considered to outweigh the risks from its side-effects.
I'm told to take this with food. Does it matter what kind of food?
Yes, it is important to take methylprednisolone with food. You should generally stick to simple foods if you experience tummy pain, indigestion, or nausea. Additionally, you should avoid drinking grapefruit juice as it is thought to increase the amount of methylprednisolone in your bloodstream, potentially making side-effects more likely.
I'm worried about getting infections while taking this medicine. What should I do?
Methylprednisolone can suppress your immune system, increasing your risk of infection. If you become ill, you should make an appointment to see your doctor straightaway. Also, if you come into contact with anyone who has measles, shingles, or chickenpox (or suspects they might have them), you must see your doctor as soon as possible.
What should I do if I think I've taken too much methylprednisolone?
Never take more than the prescribed dose. If you suspect that you or someone else might have taken an overdose of this medicine, you should go to the accident and emergency department of your local hospital immediately. Remember to take the medicine container with you, even if it is empty.
Ulteriori letture e riferimenti
- Manufacturer's PIL, Medrone® Tablets 2 mg, 4 mg; Pfizer Limited, The electronic Medicines Compendium. Dated November 2018.
- Manufacturer's PIL, Medrone® 100 mg Tablets; Pfizer Limited, Il compendio elettronico dei medicinali. Datato ottobre 2020.
- Medicinali Completi BNF 89ª Edizione; Associazione Medica Britannica e Società Farmaceutica Reale di Gran Bretagna, Londra.
Informazioni sull'autoreVisualizza il profilo completo

Michael Stewart, MRPharmS
Responsabile Revisione Foglietti Illustrativi – Contrattista, Farmacista
BPharm (Hons), MRPharmS
Michael è un farmacista comunitario che esercita nelle Midlands e nel South Yorkshire con oltre 20 anni di esperienza nel consigliare su farmaci e condizioni mediche. Ha una solida esperienza nella formazione sanitaria, avendo prodotto e tenuto corsi di formazione per team di farmacia e personale di strutture di assistenza residenziale, inclusi infermieri. Ha anche contribuito a consigli consultivi farmaceutici per la gestione di condizioni a bassa gravità nella comunità.
Informazioni sul recensore

Sid Dajani
Sultan Dajani si è laureato alla London School of Pharmacy nel 1994 ed è diventato il più giovane membro eletto del consiglio della Royal Pharmaceutical Society dalla sua fondazione nel 1842.
Storia dell'articolo
Le informazioni su questa pagina sono scritte e revisionate da clinici qualificati.
Articolo disponibile anche in Inglese, Tedesco, Spagnolo, Francese, Italiano, Portoghese, Hindi, Ebraico, Arabo, and Svedese.
Prossima revisione prevista: 19 Mar 2027
21 Set 2022 | Ultima versione

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