Acido mefenamico per dolore e infiammazione

About mefenamic acid

Antinfiammatori like mefenamic acid are also called non-steroidal anti-inflammatory drugs (NSAIDs), or sometimes just 'anti-inflammatories'. Mefenamic acid is used to treat painful conditions such as arthritis, pain associated with heavy menstrual bleeding, and pain after surgical operations.

Mefenamic acid works by blocking the effect of natural chemicals called cyclo-oxygenase (COX) enzymes. These enzymes help to make other chemicals in the body, called prostaglandins. Some prostaglandins are produced at sites of injury or damage, and cause pain and inflammation. By blocking the effect of COX enzymes, fewer prostaglandins are produced, which means pain and inflammation are eased.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking mefenamic acid, it is important that your doctor knows:

• Se hai mai avuto un'ulcera gastrica o duodenale, o se hai un disturbo infiammatorio intestinale come la malattia di Crohn o la colite ulcerosa.

• Se hai l'asma o qualsiasi altro disturbo allergico.

• Se sei incinta, stai cercando di avere un bambino o stai allattando.

• Se hai problemi con il funzionamento del tuo fegato, o se hai problemi con il funzionamento dei tuoi reni.

• Se hai una condizione cardiaca o un problema con i tuoi vasi sanguigni o la circolazione.

• Se hai la pressione alta.

• Se hai problemi di coagulazione del sangue.

• Se hai l'epilessia.

• Se hai livelli elevati di zucchero nel sangue o di colesterolo.

• Se hai un disturbo del tessuto connettivo come il lupus eritematoso sistemico. Questa è una condizione infiammatoria che è anche chiamata lupus o LES.

• Se hai un raro disturbo ereditario del sangue chiamato porfiria.

• Se stai assumendo altri medicinali. Questo include qualsiasi medicinale che stai assumendo e che è disponibile per l'acquisto senza prescrizione medica, così come i medicinali a base di erbe e complementari.

• Se hai mai avuto una reazione allergica a qualsiasi altro FANS (come aspirina, ibuprofene, diclofenac e indometacina), o a qualsiasi altro medicinale.

• Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about mefenamic acid, and it will also provide you with a full list of the side-effects which you could experience from taking it.

• Take mefenamic acid exactly as your doctor tells you to. The usual dose is 500 mg, which is taken as two 250 mg capsules, or one 500 mg tablet. You will be asked to take this dose three times a day. If you are taking it for period pain, your doctor will likely suggest that you take it for a few days each month, starting on your first day of bleeding.

• Take mefenamic acid with food. This will help to protect your stomach from side-effects such as indigestion.

• If you forget to take a dose, take it as soon as you remember unless your next dose is due. If your next dose is due, then take the dose which is due but leave out the forgotten one. Do not take two doses together to make up for a missed dose.

• Your doctor will try to prescribe you mefenamic acid for the shortest time possible to reduce the risk of side-effects. If you need to take it over a long period of time, your doctor may want to prescribe another medicine along with it to protect your stomach from irritation.

• Try to keep any regular appointments with your doctor. This is so your doctor can check on your progress. It is especially important if you are taking mefenamic acid for a long-term condition.

• If you have asthma, symptoms such as wheeze or breathlessness can be made worse by anti-inflammatories. If this happens to you, you should stop taking mefenamic acid and see your doctor as soon as possible.

• There is known to be a small increased risk of heart and blood vessel problems in people taking some anti-inflammatory painkillers long-term. Your doctor will explain this to you and will prescribe the lowest suitable dose for the shortest time in order to reduce the risk. Do not take more than the recommended dose.

• If you buy any medicines, check with a pharmacist that they are suitable for you to take. This is because you should not take mefenamic acid with any other anti-inflammatory painkiller, some of which are available in cold and flu remedies which can be bought 'over the counter'.

• Se devi sottoporti a un'operazione o a un trattamento dentistico, informa la persona che esegue il trattamento sui medicinali che stai assumendo.

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the more common ones associated with mefenamic acid. The best place to find a full list of the side-effects which can be associated with your medicine, is from the manufacturer's printed information leaflet supplied with the medicine. Alternatively, you can find an example of a manufacturer's information leaflet in the reference section below. Speak with your doctor or pharmacist if any of the following continue or become troublesome.

Importante: if you experience any of the following less common but possibly serious symptoms, stop taking mefenamic acid and contact your doctor for advice straightaway:

• Se hai difficoltà respiratorie come respiro sibilante o mancanza di respiro.

• If you have any signs of an allergic reaction such as swelling around your mouth or face, or an itchy skin rash.

• If you pass blood or black stools, bring up (vomit) blood, or have severe stomach pains.

Se si verificano altri sintomi che ritieni possano essere dovuti al medicinale, parla con il tuo medico o farmacista per ulteriori consigli.

• Tenere tutti i medicinali fuori dalla portata e dalla vista dei bambini.

• Conservare in un luogo fresco e asciutto, lontano da fonti di calore e luce diretta.