Indometacina per dolore e infiammazione

About indometacin

Indometacin a type of anti-inflammatory medicine used to treat painful conditions such as artrite, distorsioni e stiramenti, mal di schiena, period (menstrual) pain, and dolore da gotta.

Indometacin works by blocking the effect of chemicals in your body, called cyclo-oxygenase (COX) enzymes. These enzymes help to make other chemicals in the body, called prostaglandins.

Some prostaglandins are produced at sites of injury or damage, and cause pain and inflammation. By blocking the effect of COX enzymes, fewer prostaglandins are produced, which means pain and inflammation are eased.

Common side effects of indometacin are:

• Indigestione.

• heartburn.

• Dolore allo stomaco.

• Feeling sick or vomiting.

• Diarrea o stitichezza.

• Sensazione di vertigini.

You will find a full list in the manufacturer's information leaflet supplied with your medicine.

Gli effetti indesiderati spesso migliorano man mano che il tuo corpo si adatta al nuovo medicinale, ma parla con il tuo medico o farmacista se uno dei seguenti persiste o diventa problematico.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking indometacin, it is important that your doctor knows:

• Se hai l'asma o qualsiasi altro disturbo allergico.

• If you have ever had a stomach or duodenal ulcer, or if you have an inflammatory bowel disorder such as morbo di Crohn oppure colite ulcerosa.

• Se sei incinta o stai allattando.

• Se hai più di 65 anni.

• Se hai problemi al fegato o ai reni.

• Se hai una condizione cardiaca, o un problema con i tuoi vasi sanguigni o la circolazione.

• If you have ipertensione.

• If you have a high blood sugar level or cholesterol level.

• Se sei un fumatore.

• If you have epilepsy, Malattia di Parkinson, or a mental health problem.

• Se hai problemi di coagulazione del sangue.

• If you have a connective tissue disorder, such as systemic lupus erythematosus. This condition is also called lupus, or SLE.

• If you are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, such as herbal and complementary medicines.

• If you have ever had an allergic reaction to any other NSAID (such as aspirina, naprossene, diclofenac, and ibuprofene), or to any other medicine.

• Before starting indometacin, read the patient information leaflet inside the pack. It explains the strength of your capsules and lists possible side effects.

• Take indometacin exactly as your doctor has advised. Your dose and how often to take it will be shown on the label. Ask your pharmacist if you are unsure.

• Take the capsules with food or after a snack to reduce the risk of indigestion. Swallow them with a drink if needed.

• If you forget a dose, take it as soon as you remember unless it is nearly time for the next one. Do not take two doses at the same time.

• Your doctor will prescribe the lowest effective dose for the shortest possible time to reduce side effects. If you need long-term treatment, you may also be given medicine to protect your stomach.

• Keep any regular appointments with your doctor so they can check your progress, especially if you are taking indometacin long term.

• If you have asthma, anti-inflammatory medicines can sometimes worsen breathing symptoms. Stop taking indometacin and contact your doctor if this happens.

• Check with a pharmacist before taking any other medicines, including cold and flu remedies, as some contain anti-inflammatory painkillers that should not be taken with indometacin.

• Tell your doctor, dentist, or surgeon about all the medicines you are taking before any treatment or operation.

• Tenere tutti i medicinali fuori dalla portata e dalla vista dei bambini.

• Conservare in un luogo fresco e asciutto, lontano da fonti di calore e luce diretta.

How long does it take for indomethacin to work?

Indomethacin usually starts working within 1-2 hours after taking a dose. For ongoing conditions, it may take a few days of regular use to feel the full effect.

Can you drink alcohol with indomethacin?

You should avoid or limit alcohol while taking indomethacin. Drinking alcohol can increase the risk of stomach irritation, ulcers, and bleeding, and make other side effects worse.

Is it safe to take indomethacin during pregnancy?

Indomethacin is not recommended during pregnancy, especially after 20 weeks as it may cause serious complications for the unborn baby, including kidney and heart problems.

Is indomethacin a strong painkiller?

Indomethacin is considered a strong anti-inflammatory painkiller compared with many other NSAIDs. It is often used for more severe pain and inflammation, but it can cause more side effects, so it is usually prescribed with care.

How much stronger is indomethacin than ibuprofen?

Indomethacin is generally considered stronger than ibuprofen at reducing inflammation and pain. Because it is more potent, it is often used when ibuprofen has not been effective, but it also carries a higher risk of side effects.