Clotrimazolo per la candidosi vaginale
Canesten
Revisione paritaria di Sid DajaniUltimo aggiornamento di Michael Stewart, MRPharmSUltimo aggiornamento 16 Ott 2023
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Clotrimazole is an antifungal medicine.
Side-effects are unlikely but may include mild skin irritation or itching.
If your symptoms do not improve within seven days, speak with your doctor.
Do not use more than two courses of clotrimazole within six months without speaking with a doctor for further advice.
A colpo d'occhio
Clotrimazole is an antifungal medicine used to treat vaginal thrush.
It is available as creams, pessaries, or combination packs.
Insert pessaries or internal cream into the vagina and apply external cream around the vulva.
Do not rely on condoms or diaphragms for contraception for five days after use.
Speak to a doctor before use if pregnant, under 16 or over 60, or if symptoms are unusual.
See a doctor if symptoms do not improve within seven days or recur frequently.
About clotrimazole for thrush
Tipo di medicinale | Un medicinale antifungino |
Utilizzato per | Candidosi vaginale |
Chiamato anche | Canesten® |
Disponibile come | Cream, intravaginal (internal) cream, pessary, and as combination packs |
Many women have an occasional bout of candidosi vaginale. It is due to an infection with a yeast fungus called Candida spp. Most cases of thrush are caused by the yeast called Candida albicans but other types of Candida spp. can also cause thrush. Common symptoms of vaginal thrush are itching, soreness, and redness around the outside of the vagina and a thick, creamy white, odourless vaginal discharge. Clotrimazole works by killing the yeast fungus causing the infection.
Clotrimazole is usually applied in two ways to treat thrush. A pessary or internal (intravaginal) cream is inserted high into the vagina to treat the infection. Then a cream (usually containing 2% clotrimazole) is applied around the outside of the vagina to relieve the itching and soreness. Many of the products available are 'combi' packs - these contain either a pessary or internal cream, and also a cream for external use. Clotrimazole is available on prescription and you can also buy it at a pharmacy, without a prescription, if you have previously been diagnosed by your doctor as having vaginal thrush.
A lower strength of clotrimazole cream is used to treat other fungal skin infections. There is a separate medicine leaflet called Clotrimazolo per infezioni fungine della pelle which gives more information about this.
Before using clotrimazole for thrush
To make sure this is the right treatment for you, before you start using clotrimazole for thrush make sure your doctor or pharmacist knows:
If you are pregnant. This is because you should only use medicines on the recommendation of a doctor while you are expecting a baby. Also, you may need to use clotrimazole for a longer period of time during pregnancy than is usually recommended.
If you are under 16 or over 60 years of age.
If you have had more than two episodes of thrush in six months.
If you have a foul-smelling or blood-stained vaginal discharge, or if you have blisters or sores in the vaginal area.
If you are in pain, feel sick, or have diarrhoea or a fever.
If you have previously had a sexually transmitted infection, or if you have had a partner with a sexually transmitted infection.
Se hai mai avuto una reazione allergica a un medicinale.
If you are using or taking any other medicines. This includes medicines which are available to buy without a prescription, as well as herbal and complementary medicines.
How to use clotrimazole for thrush
Before starting this treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about how to use the clotrimazole preparation you have been given.
If you are using clotrimazole cream, apply the cream to the area around the outside of your vagina and back passage two or three times daily. Rub it in gently. Continue to use the cream until the itching and soreness due to the infection are gone.
If you are using clotrimazole intravaginal cream (for example, Canesten 10% VC® or Canesten® Internal Cream), insert one applicatorful high into your vagina at bedtime. A single dose is usually sufficient to treat the infection. If you are having your period, ask your doctor when you should use the cream.
If you are using a clotrimazole pessary, use the applicator to insert the pessary high up into your vagina at bedtime. Depending upon the strength of the pessary, a single dose is usually sufficient to treat the infection. If you are having your period, ask your doctor when you should use the pessary. If you are pregnant, do not use the applicator which is provided to insert the pessary, unless your doctor has recommended you to do so. Instead, use a finger to insert the pessary as high as possible.
Ottenere il massimo dal tuo trattamento
Use clotrimazole exactly as your doctor tells you to, or as directed on the pack. Remember to complete the course of treatment as this will help to prevent the infection from coming back. If your symptoms do not improve within seven days, see your doctor for further advice.
A pessary will dissolve overnight in the moisture in the vagina. If you have problems with vaginal dryness you may notice some undissolved pieces of pessary the following morning.
Clotrimazole can damage the latex in condoms and diaphragms so do not rely on these forms of contraception. Use an alternative method of contraception (or do not have sex) for at least five days after using clotrimazole. Please also keep in mind that having vaginal sex while you have thrush could infect your partner.
If after seven days your symptoms recur, you can buy a repeat course of clotrimazole from a pharmacy. If you have more than two occurrences of thrush during six months, you should speak with a doctor for further advice. An alternative treatment could be more suitable for you.
Can clotrimazole for thrush cause problems?
Clotrimazole is unlikely to cause any serious side-effects. It can occasionally cause some skin irritation, itching or stinging when it is first usedt. Stop using the product if you think this is causing problems. If you experience any other side-effects, speak with your doctor or pharmacist for further advice.
How to store clotrimazole for thrush
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Domande frequenti
How long does it take for a clotrimazole pessary to dissolve?
A pessary will dissolve overnight in the moisture naturally present in the vagina. If you experience vaginal dryness, you might notice some undissolved pieces of the pessary the following morning.
Can I use clotrimazole if I am pregnant?
If you are pregnant, you should only use medicines, including clotrimazole, on the recommendation of a doctor. You may also need to use clotrimazole for a longer period of time during pregnancy than is typically recommended. When using a pessary during pregnancy, do not use the provided applicator; instead, insert the pessary as high as possible with a finger, unless your doctor has advised otherwise.
How long after using clotrimazole for thrush should my symptoms improve?
Your symptoms should begin to improve within seven days of starting treatment. If your symptoms do not get better within this timeframe, you should see your doctor for further advice.
Can I have sex while using clotrimazole for thrush?
Clotrimazole can damage the latex in condoms and diaphragms, making them unreliable for contraception. You should use an alternative method of contraception, or avoid sexual intercourse, for at least five days after using clotrimazole. Additionally, having vaginal sex while you have thrush could infect your partner.
What should I do if my thrush symptoms come back after treatment?
If your symptoms recur after seven days, you can purchase a repeat course of clotrimazole from a pharmacy. However, if you experience more than two episodes of thrush within a six-month period, you should consult a doctor for further advice, as an alternative treatment might be more suitable for you.
Ulteriori letture e riferimenti
- Manufacturer's PIL, Canesten® Thrush Internal Cream 10% w/w vaginal cream; Bayer plc, The electronic Medicines Compendium. Dated March 2021.
- Manufacturer's PIL, Canesten® 500 mg Vaginal Pessary; Bayer plc, The electronic Medicines Compendium. Dated February 2023.
- Manufacturer's PIL, Canesten® Thrush External Cream 2% w/w; Bayer Plc, The electronic Medicines Compendium. Dated February 2021.
- Medicinali Completi BNF 89ª Edizione; Associazione Medica Britannica e Società Farmaceutica Reale di Gran Bretagna, Londra.
Informazioni sull'autoreVisualizza il profilo completo

Michael Stewart, MRPharmS
Responsabile Revisione Foglietti Illustrativi – Contrattista, Farmacista
BPharm (Hons), MRPharmS
Michael è un farmacista comunitario che esercita nelle Midlands e nel South Yorkshire con oltre 20 anni di esperienza nel consigliare su farmaci e condizioni mediche. Ha una solida esperienza nella formazione sanitaria, avendo prodotto e tenuto corsi di formazione per team di farmacia e personale di strutture di assistenza residenziale, inclusi infermieri. Ha anche contribuito a consigli consultivi farmaceutici per la gestione di condizioni a bassa gravità nella comunità.
Informazioni sul recensore

Sid Dajani
Sultan Dajani si è laureato alla London School of Pharmacy nel 1994 ed è diventato il più giovane membro eletto del consiglio della Royal Pharmaceutical Society dalla sua fondazione nel 1842.
Storia dell'articolo
Le informazioni su questa pagina sono scritte e revisionate da clinici qualificati.
Articolo disponibile anche in Inglese, Tedesco, Spagnolo, Francese, Italiano, Portoghese, Hindi, Ebraico, Arabo, and Svedese.
Prossima revisione prevista: 15 Ott 2026
16 Ott 2023 | Ultima versione

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