Clomethiazole
Revisione paritaria di Sid DajaniUltimo aggiornamento di Michael Stewart, MRPharmSUltimo aggiornamento 9 Nov 2022
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Swallow the capsules whole with a drink of water. Do not chew them.
Clomethiazole will make you sleepy. If you still feel sleepy the next day, do not drive and do not use tools or machines.
Do not drink alcohol whilst being treated with clomethiazole.
The most common side-effects are a runny or blocked nose, and headache. These should soon pass.
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About clomethiazole
Tipo di medicinale | Hypnotic and sedative |
Utilizzato per | Insomnia, restlessness, or agitation, particularly in elderly people Sintomi di astinenza da alcol |
Disponibile come | Capsules and oral liquid medicine |
Insomnia, or poor sleep, is fairly common. If you have problems sleeping, it may mean that you have difficulty getting off to sleep, or you may wake up for long periods during the night, or you may wake up too early in the morning. 'Sleeping pills' like clomethiazole are considered a last resort, but are sometimes prescribed for a short period of time to help with a particularly bad spell of insomnia.
Clomethiazole is also prescribed in certain circumstances to help calm elderly people who are particularly restless or agitated. It is also used within specialist dependency units to relieve the symptoms of astinenza da alcol.
Before taking clomethiazole
Torna ai contenutiSome medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking clomethiazole it is important that your doctor or pharmacist knows:
Se sei incinta o stai allattando.
If you have a heart condition, or liver or kidney problems.
If you have lung or breathing problems or a problem where you stop breathing for short periods at night (sleep apnoea).
If you have ever had a drug addiction or a personality disorder.
Se stai assumendo altri medicinali. Questo include qualsiasi medicinale che stai assumendo e che è disponibile per l'acquisto senza prescrizione medica, così come i medicinali a base di erbe e complementari.
Se hai mai avuto una reazione allergica a un medicinale.
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How to take clomethiazole
Torna ai contenutiBefore you start this treatment, read the manufacturer's printed information leaflet from inside your pack. The leaflet will give you more information about clomethiazole and a full list of side-effects which you may experience from taking it.
Take clomethiazole exactly as your doctor tells you to. Your dose will be on the label of the pack to remind you:
If you have been prescribed clomethiazole for insomnia, your doctor may recommend that you take one or two capsules each evening, or only on certain days of the week. Take the capsules just before you go to bed.
If you have been prescribed clomethiazole to help calm restlessness or agitation, your doctor is likely to recommend that you take one capsule three times daily, for a short period of time.
If you have been prescribed clomethiazole to help reduce alcohol withdrawal symptoms, your doctor or clinic will tell you how to take it.
If you have been prescribed capsules, swallow them whole with a drink of water. Do not chew them.
If you have been prescribed the oral liquid medicine it should be diluted with water or juice and swallowed immediately. Measure the correct amount of medicine for your dose and add it to a glass. Mix well with water or juice and ensure you drink the entire contents of the glass. Do not use plastic containers to mix your medicine in.
If you forget to take a dose, take it as soon as you remember unless it is nearly time for your next dose, in which case skip the missed dose. Do not take two doses together to make up for a forgotten dose.
Ottenere il massimo dal tuo trattamento
Torna ai contenutiCerca di mantenere i tuoi appuntamenti regolari con il tuo medico. Questo è per permettere al tuo medico di controllare i tuoi progressi.
Clomethiazole will make you sleepy. If you still feel sleepy the next day, do not drive and do not use tools or machines.
Do not drink alcohol whilst being treated with clomethiazole.
Clomethiazole is only recommended for a short period of time. This is because your body can become dependent on it after a while. This can cause problems when you then stop taking it.
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Can clomethiazole cause problems?
Torna ai contenutiAlong with their useful effects, all medicines can cause unwanted side-effects although not everyone experiences them. The table below lists some of the most common ones associated with clomethiazole. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve over the first few days of taking a new medicine, but speak with your doctor or pharmacist if any of the following side-effects continue or become troublesome.
Common clomethiazole side-effects | Cosa posso fare se sperimento questo? |
Mal di testa | Bevi molta acqua e chiedi al tuo farmacista di consigliarti un antidolorifico adatto. Se i mal di testa persistono, informa il tuo medico |
A runny or blocked nose, sore eyes | These can occur soon after taking a dose, but usually quickly pass |
Se si verificano altri sintomi che ritieni possano essere dovuti a questo medicinale, parla con il tuo medico o farmacista.
How to store clomethiazole
Torna ai contenutiTenere tutti i medicinali fuori dalla portata e dalla vista dei bambini.
Store the capsules in a cool, dry place, away from direct heat and light.
If you are using the oral liquid medicine it should be kept in its original container and stored in a refrigerator.
Informazioni importanti su tutti i medicinali
Torna ai contenutiInformazioni importanti su tutti i medicinali
Se acquisti dei medicinali, verifica con un farmacista che siano sicuri da assumere insieme agli altri tuoi medicinali.
Non assumere mai più della dose prescritta. Se sospetti che tu o qualcun altro possa aver assunto un sovradosaggio di questo medicinale, recati al pronto soccorso del tuo ospedale locale. Porta con te il contenitore, anche se è vuoto.
Se devi sottoporti a un'operazione o a un trattamento dentistico, informa la persona che esegue il trattamento sui medicinali che stai assumendo.
Questo medicinale è per te. Non darlo mai ad altre persone, anche se la loro condizione sembra essere la stessa della tua.
Non conservare medicinali scaduti o indesiderati. Portali alla tua farmacia locale che li smaltirà per te.
Se hai domande su questo medicinale, chiedi al tuo farmacista.
Segnala effetti collaterali di un medicinale o vaccino
Se si verificano effetti collaterali, è possibile segnalarli online tramite il Yellow Card website.

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Ulteriori letture e riferimenti
- Manufacturer's PIL, Clomethiazole 31.5 mg/ml Syrup; Neon Healthcare Ltd, The electronic Medicines Compendium. Dated October 2020.
- Manufacturer's PIL, Clomethiazole 192 mg Capsules; Neon Healthcare Ltd, The electronic Medicines Compendium. Dated October 2020.
- Medicinali Completi BNF 89ª Edizione; Associazione Medica Britannica e Società Farmaceutica Reale di Gran Bretagna, Londra.
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About the author

Michael Stewart, MRPharmS
Medicine Leaflet Review Manager – Contractor, Pharmacist
BPharm (Hons), MRPharmS
Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.
About the reviewer

Sid Dajani
Storia dell'articolo
Le informazioni su questa pagina sono scritte e revisionate da clinici qualificati.
Prossima revisione prevista: 8 maggio 2027
9 Nov 2022 | Ultima versione

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