Loprazolam per problemi di sonno
Revisione paritaria di Sid DajaniUltimo aggiornamento di Michael Stewart, MRPharmSUltimo aggiornamento 19 Dic 2022
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Loprazolam will help you to sleep. You will be prescribed a short course of treatment only.
Take the tablet just before you go to bed.
The effects of loprazolam can last into the following day; it is likely to impair your reactions and your ability to drive. Do not drive and do not use tools or machines while affected.
A colpo d'occhio
Loprazolam is a benzodiazepine medicine for adults with sleeping problems called insomnia.
It is usually prescribed for short periods, often one to three weeks.
Take one tablet just before bed, exactly as your doctor tells you.
Do not drink alcohol or drive while taking loprazolam.
Taking loprazolam for too long can lead to dependence and addiction.
Side-effects can include daytime sleepiness, unsteadiness, or confusion.
Always tell your doctor about other medicines you are taking.
About loprazolam
Tipo di medicinale | Un benzodiazepina |
Utilizzato per | Sleeping problems (insomnia) in adults |
Disponibile come | Compresse |
Poor sleep (insomnia) is fairly common but does not usually last for long. If you have problems sleeping, it may mean that you have difficulty getting off to sleep, or you may wake up for long periods during the night, or you may wake up too early in the morning. 'Sleeping tablets' like loprazolam are considered a last resort, but are sometimes prescribed for a short period of time to help with a particularly bad spell of insomnia.
Loprazolam works by affecting the way certain brain chemicals (neurotransmitters) transmit messages. This has a calming effect which helps you to sleep. It works well in the short term, with one week's treatment normally being sufficient, although up to three weeks of treatment are sometimes required. If you take it for longer, the medicine may lose its effect (you may become tolerant to the effect) and when you stop taking it you may develop withdrawal symptoms. You may need to keep taking the medicine to avoid the withdrawal symptoms. This is known as drug dependence.
In addition, you may become addicted to loprazolam. Addiction is different from dependence. You have an overwhelming craving for a drug, so that you feel compelled to take it even though it is harming you physically or affecting your life and relationships.
Before taking loprazolam
Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking loprazolam it is important that your doctor knows:
Se sei incinta o stai allattando.
Se hai problemi respiratori.
Se hai problemi con il funzionamento del tuo fegato, o se hai problemi con il funzionamento dei tuoi reni.
If you have a mental health problem. This includes conditions such as psychosis, depression, and personality disorders.
Se hai mai avuto una dipendenza da droga o alcol.
Se hai una condizione che causa una grave debolezza muscolare, chiamata miastenia grave.
Se hai un raro disturbo ereditario del sangue chiamato porfiria.
Se hai mai avuto una reazione allergica a un medicinale.
Se stai assumendo altri medicinali. Questo include qualsiasi medicinale disponibile per l'acquisto senza prescrizione, così come i medicinali a base di erbe e complementari.
How to take loprazolam
Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about loprazolam, and it will also provide you with a full list of the side-effects which you could experience from taking it.
The usual dose is one tablet (1 mg) taken just before going to bed. Your doctor may recommend that you take a dose for just a few days, or only on certain days of the week. It is important that you take loprazolam exactly as your doctor tells you to.
Ottenere il massimo dal tuo trattamento
Try to keep any appointments with your doctor. This is so your doctor can check how you are feeling.
The effects of loprazolam can last into the following day; please be aware that it is likely to impair your judgement and reactions, and so affect your ability to drive. It is an offence to drive while your reactions are impaired, so do not drive until you know how you react, especially when you first start treatment. Even if your driving ability is not impaired, should you drive, you are advised to carry with you some evidence that the medicine has been prescribed for you - a repeat prescription form or a patient information leaflet from the pack is generally considered suitable.
Do not drink alcohol while you are on loprazolam. It will increase the risk of sedative side-effects.
If you are due to have an operation or any dental treatment, please tell the person carrying out the treatment that you are taking a benzodiazepine. This is because loprazolam increases the effects of some anaesthetics.
Your doctor may recommend that you reduce your dose gradually when it is time to stop taking it. This is to reduce the risk of you experiencing withdrawal effects. Follow carefully any instructions your doctor gives to you.
Can loprazolam cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the more common ones associated with loprazolam. The best place to find a full list of the side-effects which can be associated with your medicine, is from the manufacturer's printed information leaflet supplied with the medicine. Alternatively, you can find an example of a manufacturer's information leaflet in the reference section below. Speak with your doctor or pharmacist if any of the following continue or become troublesome.
Common loprazolam side-effects | Cosa posso fare se sperimento questo? |
Feeling sleepy or light-headed during the day | Non guidare e non utilizzare strumenti o macchinari. Non bere alcolici |
Feeling unsteady, weak, forgetful, confused, or aggressive | Se dovessero causare problemi, consultate il vostro medico |
Headache, feeling sick (nausea), blurred vision | These should soon pass, but if any are troublesome or you are concerned about them, please speak with your doctor |
Se si verificano altri sintomi che ritieni possano essere dovuti alle compresse, parla con il tuo medico o farmacista per ulteriori consigli.
How to store loprazolam
Tenere tutti i medicinali fuori dalla vista e dalla portata dei bambini.
Conservare in un luogo fresco e asciutto, lontano da fonti di calore e luce diretta.
Informazioni importanti su tutti i medicinali
Informazioni importanti su tutti i medicinali
Se acquisti dei medicinali, verifica con un farmacista che siano sicuri da assumere insieme agli altri tuoi medicinali.
Non assumere mai più della dose prescritta. Se sospetti che tu o qualcun altro possa aver assunto un sovradosaggio di questo medicinale, recati al pronto soccorso del tuo ospedale locale. Porta con te il contenitore, anche se è vuoto.
Se devi sottoporti a un'operazione o a un trattamento dentistico, informa la persona che esegue il trattamento sui medicinali che stai assumendo.
Questo medicinale è per te. Non darlo mai ad altre persone, anche se la loro condizione sembra essere la stessa della tua.
Non conservare medicinali scaduti o indesiderati. Portali alla tua farmacia locale che li smaltirà per te.
Se hai domande su questo medicinale, chiedi al tuo farmacista.
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Domande frequenti
What is the typical starting dose of loprazolam?
The usual dose of loprazolam is one tablet, which is 1 mg, taken just before going to bed. Your doctor might suggest taking it for only a few days, or only on specific days of the week, depending on your needs. It's important to follow your doctor's instructions precisely.
What should I do if I forget to tell a healthcare professional I'm taking loprazolam before an operation or dental work?
If you are due to have an operation or any dental treatment, it is important to tell the person carrying out the treatment that you are taking a benzodiazepine like loprazolam. This is because loprazolam can increase the effects of some anaesthetics. If you forget, try to inform them as soon as possible.
Where can I find a complete list of all possible side effects of loprazolam?
A full list of all possible side effects associated with loprazolam can be found in the manufacturer's printed information leaflet that comes inside the medicine pack. You can also ask your doctor or pharmacist for this information.
What is the difference between drug dependence and addiction when taking loprazolam?
Drug dependence means that the medicine may lose its effect over time, and when you stop taking it, you might experience withdrawal symptoms. To avoid these symptoms, you may feel the need to keep taking the medicine. Addiction, on the other hand, is an overwhelming craving for the drug, where you feel compelled to take it even if it causes physical harm or negatively impacts your life and relationships.
Why is it important for my doctor to know if I have mental health conditions before prescribing loprazolam?
It's important your doctor knows if you have a mental health problem, such as psychosis, depression, or personality disorders, because certain medicines are not suitable for people with specific conditions, or may require extra care during use. This information helps your doctor determine if loprazolam is safe and appropriate for you.
Ulteriori letture e riferimenti
- Manufacturer's PIL, Loprazolam 1 mg Tablets; Zentiva, The electronic Medicines Compendium. Dated March 2022.
- Medicinali Completi BNF 89ª Edizione; Associazione Medica Britannica e Società Farmaceutica Reale di Gran Bretagna, Londra.
Informazioni sull'autoreVisualizza il profilo completo

Michael Stewart, MRPharmS
Responsabile Revisione Foglietti Illustrativi – Contrattista, Farmacista
BPharm (Hons), MRPharmS
Michael è un farmacista comunitario che esercita nelle Midlands e nel South Yorkshire con oltre 20 anni di esperienza nel consigliare su farmaci e condizioni mediche. Ha una solida esperienza nella formazione sanitaria, avendo prodotto e tenuto corsi di formazione per team di farmacia e personale di strutture di assistenza residenziale, inclusi infermieri. Ha anche contribuito a consigli consultivi farmaceutici per la gestione di condizioni a bassa gravità nella comunità.
Informazioni sul recensore

Sid Dajani
Sultan Dajani si è laureato alla London School of Pharmacy nel 1994 ed è diventato il più giovane membro eletto del consiglio della Royal Pharmaceutical Society dalla sua fondazione nel 1842.
Storia dell'articolo
Le informazioni su questa pagina sono scritte e revisionate da clinici qualificati.
Articolo disponibile anche in Inglese, Tedesco, Spagnolo, Francese, Italiano, Portoghese, Hindi, Ebraico, Arabo, and Svedese.
Prossima revisione prevista: 18 giu 2027
19 Dic 2022 | Ultima versione

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