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Procyclidine

Kemadrin

Procyclidine is used to relieve unwanted side-effects caused by antipsychotic medicines. It may also be used in the early stages of Parkinson's disease.

It is usually prescribed as a three times daily dose, but you may be advised to take it more or less often than this. Take it exactly as your doctor tells you to.

The most common side-effects are a dry mouth, constipation, blurred vision and difficulties passing urine.

About procyclidine

Tipo di medicinale

An antimuscarinic medicine

Utilizzato per

Unwanted 'extrapyramidal side-effects' caused by some medicines, Parkinson's disease and Parkinsonism

Chiamato anche

Kemadrin®

Disponibile come

Tablets, oral liquid and injection

Procyclidine is used to relieve unwanted side-effects caused by some antipsychotic medicines. Antipsychotic medicines are prescribed for mental health problems such as schizofrenia. As a side-effect of treatment, antipsychotic medicines can sometimes cause unwanted body movements, some of which may be severe. These movement disorders are often referred to as 'extrapyramidal side-effects' or 'Parkinsonism' and include things like uncontrolled face and body movements, shakiness (tremor), and restlessness. Procyclidine is prescribed to relieve these types of symptoms.

Procyclidine is also used to relieve some of the symptoms of Malattia di Parkinson, which include movement problems such as stiff muscles, shakiness (tremor) and eye movements, as well as sweating and producing too much saliva.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking procyclidine it is important that your doctor knows:

  • Se sei incinta, stai cercando di avere un bambino o stai allattando.

  • Se hai problemi con il funzionamento del tuo fegato o dei tuoi reni.

  • If you have any problems with your heart or blood vessels.

  • If you have prostate problems, or if you have been experiencing difficulty passing urine.

  • If you have been constipated for more than a week or if you have been told you have an obstruction in your bowel.

  • If you have a condition which causes raised pressure in your eyes, such as glaucoma.

  • Se hai la pressione alta (ipertensione).

  • Se hai una condizione che causa debolezza muscolare, chiamata miastenia grave.

  • If you have ever had a mental health problem called psychosis.

  • Se stai assumendo altri medicinali. Questo include qualsiasi medicinale che stai assumendo e che è disponibile per l'acquisto senza prescrizione medica, così come i medicinali a base di erbe e complementari.

  • Se hai mai avuto una reazione allergica a un medicinale.

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  • Before you start this treatment, read the manufacturer's printed information leaflet from inside your pack. The manufacturer's leaflet will give you more information about procyclidine and a full list of the side-effects which you may experience from taking it.

  • Take procyclidine exactly as your doctor tells you to. When starting your treatment your doctor will give you a small dose (usually half a tablet or 5 ml liquid medicine three times daily), and then may gradually increase your dose.

  • Carefully follow the directions your doctor gives to you. Although procyclidine is usually prescribed as a three times daily dose, you may be advised to take it more or less often than this.

  • It is not important whether you take procyclidine before or after food, although some people find taking it with meals helps prevent feelings of sickness (nausea).

  • Try to take your doses of procyclidine at the same times of day, each day. This will help you to remember to take your doses regularly.

  • If you do forget to take a dose, take it as soon as you remember unless it is nearly time for your next dose, in which case leave out the missed dose. Do not take two doses together to make up for a missed dose.

  • Cerca di mantenere i tuoi appuntamenti regolari con il tuo medico. Questo è per permettere al tuo medico di controllare i tuoi progressi.

  • If you buy any medicines, check with a pharmacist that they are safe to take with procyclidine. Some antihistamines and some strong painkillers can interfere with procyclidine and increase the risk of side-effects.

  • If you are having an operation or any dental treatment, tell the person carrying out the treatment that you are taking procyclidine.

  • If you have been taking procyclidine for some time, do not stop taking it without speaking with your doctor first. Stopping suddenly can cause problems so your doctor will want to reduce your dose gradually when this is necessary.

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Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with procyclidine. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Common procyclidine side-effects - these affect fewer than 1 in 10 people


Cosa posso fare se sperimento questo?

Bocca secca

Prova a masticare gomme senza zucchero o a succhiare caramelle senza zucchero

Costipazione

Try to eat a well-balanced diet and drink several glasses of water each day

Blurred vision, feeling dizzy

Do not drive and do not use tools or machines until you feel better

Difficulty passing urine

If this becomes troublesome, let your doctor know

Less common procyclidine side-effects - these affect fewer than 1 in 100 people

Cosa posso fare se sperimento questo?

Sensazione di malessere (nausea) o vomito

Stick to simple foods - avoid rich or spicy meals. Try taking procyclidine after meals if you are not already doing so

A fast heartbeat, skin rash, mood changes, and feeling anxious, confused or forgetful

If any of these become troublesome, let your doctor know

Se si verificano altri sintomi che ritieni possano essere dovuti a questo medicinale, parla con il tuo medico o farmacista.

  • Tenere tutti i medicinali fuori dalla portata e dalla vista dei bambini.

  • Conservare in un luogo fresco e asciutto, lontano da fonti di calore e luce diretta.

Informazioni importanti su tutti i medicinali

Non assumere mai più della dose prescritta. Se sospetti che tu o qualcun altro possa aver assunto un sovradosaggio di questo medicinale, recati al pronto soccorso del tuo ospedale locale. Porta con te il contenitore, anche se è vuoto.

Questo medicinale è per te. Non darlo mai ad altre persone, anche se la loro condizione sembra essere la stessa della tua.

Non conservare medicinali scaduti o indesiderati. Portali alla tua farmacia locale che li smaltirà per te.

Se hai domande su questo medicinale, chiedi al tuo farmacista.

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Storia dell'articolo

Le informazioni su questa pagina sono scritte e revisionate da clinici qualificati.

  • Next review due: 23 Feb 2026
  • 24 Feb 2023 | Ultima versione

    Ultimo aggiornamento di

    Michael Stewart, MRPharmS

    Revisione paritaria di

    Sid Dajani
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