Capsule di acitretina per la psoriasi
Neotigason
Revisione paritaria di Sid DajaniUltimo aggiornamento di Michael Stewart, MRPharmSUltimo aggiornamento 20 Sept 2024
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Acitretin will be prescribed for you by a skin specialist doctor.
Take your doses during a mealtime. Swallow the capsule(s) with a drink of milk or water.
Avoid bright sunlight or use a high-factor sun cream (SPF 15 or greater). Do not use sunbeds.
Acitretin is harmful to unborn babies. You MUST use effective contraception if you could get pregnant.
A colpo d'occhio
Acitretin is a retinoid medicine, similar to vitamin A.
It treats severe psoriasis and other skin conditions by helping skin grow more normally.
Take capsules once daily with food, exactly as your doctor tells you.
Women must not become pregnant during treatment and for three years afterwards.
Acitretin can make your skin more sensitive to sunlight, so protect your skin.
Common side-effects include dry skin, lips, mouth and eyes.
About acitretin
Tipo di medicinale | A retinoid medicine (similar to vitamin A) |
Utilizzato per | Severe psoriasis and some other skin conditions |
Chiamato anche | Neotigason® |
Disponibile come | Capsule |
Acitretin is used to treat severe skin conditions where the surface of the skin has become thick and scaly. Normally, as new skin cells are produced, older ones are lost. If the skin cells in the outer layer of your skin multiply faster than normal, the old skin cells can build up on the surface of your skin, causing thick or scaly patches.
Acitretin is a retinoid medicine, which means simply that it is related to vitamin A. Our bodies use vitamin A to maintain a healthy skin. Acitretin helps to control conditions like psoriasi by making your skin grow more normally.
Acitretin is sometimes used as a treatment on its own but, more often, it is used alongside other preparations to help the skin's condition.
Before taking acitretin
Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking acitretin it is important that your doctor knows:
If you are pregnant, trying for a baby or breastfeeding. This is because you must fare affidamento take acitretin if you think you are (or think you may be) pregnant.
Se hai problemi con il funzionamento del tuo fegato, o problemi con il funzionamento dei tuoi reni.
If you have high levels of fats (lipids) such as cholesterol in your blood.
Se hai il diabete (diabete mellito).
Se stai assumendo o utilizzando altri medicinali. Questo include qualsiasi medicinale che stai assumendo e che è disponibile per l'acquisto senza prescrizione, così come i medicinali a base di erbe e complementari.
Se hai mai avuto una reazione allergica a un medicinale.
How to take acitretin
Before you start the treatment, read the manufacturer's printed information leaflet from inside your pack and any other information that you are given by your doctor. The leaflets will give you more information about acitretin and will provide you with a full list of the side-effects which you could experience from taking it.
Take the capsules exactly as your doctor tells you to. Acitretin is taken once daily. Your doctor will tell you how many capsules to take and this will also be printed on the label of the pack to remind you about what the doctor said to you. Take each of your doses with a snack, or just after eating a meal. It is a good idea to swallow the capsules with a drink of water or milk.
Try to take your doses of acitretin at the same time of day each day, as this will help you to remember to take them regularly. If you forget to take a dose at the usual time, take it when you remember. If you do not remember until the following day, then miss out the forgotten dose. Do not take two doses together to make up for a missed dose.
Ottenere il massimo dal tuo trattamento
It is important for you to keep your regular appointments with your doctor. This is so your doctor can check on your progress. You will need to have regular blood tests during the treatment. The tests will check that your lipid levels are normal and that your liver remains healthy. If you are a woman, you may also need to have regular tests to confirm that you are not pregnant.
It can take 2-4 weeks before you start to feel the benefit from the capsules and it may take up to four months before you feel the maximum benefit. A course of treatment is likely to last for up to six months but occasionally it can be for longer than this.
Acitretin is harmful to unborn babies, so it is very important that you do not become pregnant while you are taking it. Your doctor will advise you about suitable contraception and this may include using more than one method. You should continue to use suitable contraception for at least three years after you finish your course of treatment. If at any time during your treatment or the three years afterwards, you think you may be pregnant, contact your doctor for advice straightaway.
If you buy any medicines, vitamins, or herbal preparations, please check with your doctor or a pharmacist that they are suitable for you to take with acitretin. This is because you must not take any other preparation which contains vitamin A.
Acitretin can cause your skin to become more sensitive to sunlight than normal. Protect your skin from sunlight even on bright but cloudy days and do not use sunbeds.
If you normally drink alcohol, please ask your doctor for advice. Your doctor may recommend that you do not drink alcohol while you are on this medicine.
If you have diabetes you may need to check your blood sugar (glucose) more frequently, as acitretin can affect the levels of sugar in your blood. Your doctor will advise you about this.
You must not give blood while you are on acitretin and for at least three years after you finish taking it. This is because it could cause harm to other people.
Can acitretin cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with acitretin. You will find a full list in the manufacturer's information leaflet supplied with the medicine. The unwanted effects often improve as your body adjusts to the new medicine but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Common acitretin side-effects (these affect around 1 in 10 people) | Cosa posso fare se sperimento questo? |
Dry mouth, feeling thirsty, sore mouth | Try chewing sugar-free gum or sucking sugar-free sweets. If this continues, ask your doctor for advice |
Dry or irritated eyes, blurred vision, and reduced night vision | Take extra care when driving at night. If this becomes troublesome, speak with your doctor |
Dry skin and lips, peeling | Use a moisturising cream and lip balm regularly. After peeling, the new skin often appears more normal |
Tummy (abdominal) pain, feeling sick (nausea), diarrhoea | Stick to simple meals (avoid rich or spicy foods). Drink plenty of water to replace any lost fluids |
Dolore muscolare e articolare | Let your doctor know about this so that it can be investigated |
Mal di testa | Bevi molta acqua e chiedi al tuo farmacista di consigliarti un antidolorifico adatto. Se i mal di testa persistono, informa il tuo medico |
Dry or irritated nose, nosebleeds, weak nails, swollen feet and ankles, mood changes, loss of hair and changes in hair texture | Se uno di questi diventa problematico, parla con il tuo medico |
If you experience any other symptoms which you think may be due to the capsules, please speak with your doctor or pharmacist for further advice.
How to store acitretin
Tenere tutti i medicinali fuori dalla portata e dalla vista dei bambini.
Conservare in un luogo fresco e asciutto, lontano da fonti di calore e luce diretta.
Informazioni importanti su tutti i medicinali
Informazioni importanti su tutti i medicinali
Se devi sottoporti a un'operazione o a un trattamento dentistico, informa la persona che esegue il trattamento su quali medicinali stai assumendo o utilizzando.
Non assumere mai più della dose prescritta. Se sospetti che tu o qualcun altro possa aver assunto un sovradosaggio di questo medicinale, recati al pronto soccorso del tuo ospedale locale. Porta con te il contenitore, anche se è vuoto.
Questo medicinale è per te. Non darlo mai ad altre persone, anche se la loro condizione sembra essere la stessa della tua.
Non conservare medicinali scaduti o indesiderati. Portali alla tua farmacia locale che li smaltirà per te.
Se hai domande su questo medicinale, chiedi al tuo farmacista.
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Domande frequenti
Can I take acitretin if I have diabetes?
If you have diabetes, your doctor needs to be aware of this before you start taking acitretin. You may need to monitor your blood sugar (glucose) levels more frequently, as this medication can affect them. Your doctor will provide specific advice on managing this.
How long will I need to be on acitretin treatment?
A typical course of treatment with acitretin is likely to last for up to six months. However, in some cases, your doctor may decide to extend the treatment for a longer period.
What should I do if my skin becomes very dry due to acitretin?
Dry skin and lips are common side-effects of acitretin. To manage this, you should regularly use a moisturising cream and lip balm. It's often observed that after an initial period of peeling, new skin appears more normal.
Why do I need regular blood tests while taking acitretin?
Regular blood tests are essential to monitor your progress and ensure your safety while on acitretin. These tests help your doctor check that your lipid levels (fats like cholesterol) remain normal and that your liver is functioning healthily. If you are a woman, regular tests may also be needed to confirm you are not pregnant.
Can I use sunbeds while taking acitretin?
No, you must not use sunbeds while taking acitretin. This medication can make your skin much more sensitive to sunlight, so it's important to protect your skin from the sun, even on bright but cloudy days.
What kind of drinks should I take with acitretin capsules?
It is a good idea to swallow acitretin capsules with a drink of water or milk. This should be done with a snack or just after eating a meal.
Ulteriori letture e riferimenti
- Manufacturer's PIL, Acitretin 10 mg and 25 mg Capsules; Genus Pharmaceuticals Ltd, The electronic Medicines Compendium. Dated December 2023.
- Medicinali Completi BNF 89ª Edizione; Associazione Medica Britannica e Società Farmaceutica Reale di Gran Bretagna, Londra.
Informazioni sull'autoreVisualizza il profilo completo

Michael Stewart, MRPharmS
Responsabile Revisione Foglietti Illustrativi – Contrattista, Farmacista
BPharm (Hons), MRPharmS
Michael è un farmacista comunitario che esercita nelle Midlands e nel South Yorkshire con oltre 20 anni di esperienza nel consigliare su farmaci e condizioni mediche. Ha una solida esperienza nella formazione sanitaria, avendo prodotto e tenuto corsi di formazione per team di farmacia e personale di strutture di assistenza residenziale, inclusi infermieri. Ha anche contribuito a consigli consultivi farmaceutici per la gestione di condizioni a bassa gravità nella comunità.
Informazioni sul recensore

Sid Dajani
Sultan Dajani si è laureato alla London School of Pharmacy nel 1994 ed è diventato il più giovane membro eletto del consiglio della Royal Pharmaceutical Society dalla sua fondazione nel 1842.
Storia dell'articolo
Le informazioni su questa pagina sono scritte e revisionate da clinici qualificati.
Articolo disponibile anche in Inglese, Tedesco, Spagnolo, Francese, Italiano, Portoghese, Hindi, Ebraico, Arabo, and Svedese.
Prossima revisione prevista: 25 Set 2027
20 Sept 2024 | Ultima versione

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