
Gli integratori possono aiutare a gestire il diabete?
Revisione paritaria di Michael Stewart, MRPharmSAutore Victoria RawPubblicato originariamente 4 Dec 2024
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According to Diabetes UK, some people with diabetes believe that certain vitamins and supplements may help manage their blood sugar levels. While they shouldn't be a substitute for conventional treatment, here’s a look at some of the most commonly used supplements, and their purported benefits.
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Diabete is a condition that makes your blood sugar (glucose) too high. This happens when your pancreas produces little or no insulin - a hormone crucial for regulating blood sugar levels.
There are two types of diabetes:
Tipo 1 - your body makes very little insulin or no insulin at all.
Tipo 2 - your body either produces too little insulin, or your tissues are not sensitive enough to insulin's effects.
Managing and treating diabetes requires a combination of healthy eating, regular exercise, and medicine - including insulin. Vitamins and supplements are becoming increasingly popular as complementary additions alongside tried and tested diabetes treatments. However, there is limited research - and no solid evidence - to confirm their beneficial effects on diabetes management.
Diabete

Grafica: Ben Hudson
Supplements and vitamins for diabetes
Pharmacist and nutritional therapist Deborah Grayson, Practice With Confidence says that any supplement that increases the sensitivity of your body to insulin, or lowers your blood sugar levels, may interact with diabetes medicines.
This could lead to poorer blood sugar control, and could even make complications arising from diabetes worse.
Grayson recommends you seek advice from your doctor, pharmacist, or a registered nutritional therapist before taking supplements alongside your conventional diabetes medicine.
Vitamin B12
Vitamin B12 is often depleted when taking metformin to control type 2 diabetes. A carenza di vitamina B12 can lead to issues with memory and peripheral neuropathy - a condition that affects the nerve signals between your brain and spinal cord.
Grayson says: "Getting a blood test to check your vitamin B12 levels is recommended if you suspect this may be the case."
Magnesium
Low levels of magnesium are often linked to higher blood sugar levels in people with diabetes. For this reason, magnesium is thought to help insulin function better.
Grayson says: "Magnesium supplementation can lower blood pressure and cause diarrhoea, depending on the form in which it is taken. Metformin - a medicine used in the treatment of diabetes - can impact the absorption and retention of magnesium, especially if it's causing diarrhoea."
Zinc
Zinc is believed to boost insulin production, and improve its interactions with your body's cells. It may also reduce inflammation, and protect your pancreas - the organ that makes insulin.
Grayson says: "Despite these reported benefits, there's a chance that zinc could cause nausea in some people. It can also prevent the absorption of medicine - including antibiotics and thyroid treatment. It should be taken at least 2 hours before or after antibiotics, and 4 hours before or after thyroid medicine."
Selenio
A powerful antioxidant, selenium is thought to safeguard your pancreas from damage, enhancing its ability to produce enough insulin.
Grayson says: "Selenium can be toxic if taken over the recommended daily dosage - a maximum of 200 micrograms."
Vitamina D
Vitamin D deficiency has been linked to an increased chance of developing type 2 diabetes. Vitamin D is made by your body in the summer, but you may need to take a supplement during the winter.
Vitamina C
Vitamina C may have a positive effect on blood sugar control and insulin sensitivity. It could also lower inflammation and oxidative stress which could contribute to the development of type 2 diabetes.
Grayson warns that having too much vitamin C can lead to diarrhoea - especially at doses of 1 gram or higher.
Inositol
Inositols are compounds that improve insulin sensitivity and play a role in regulating human reproduction.
Myo-inositol is a supplement that works in a similar way to metformin. It decreases glucose absorption in your digestive system and enhances glucose transport into cells by improving insulin sensitivity.
Grayson says: "Myo-inositol can increase your likelihood of ipoglicemia. It can also cause digestive upset - such as diarrhoea and bloating."
Berberine
Berberine may increase insulin secretion, and reduce glucose production in your liver, and fat storage.
Grayson says: "Berberine can heighten your chance of hypoglycaemia, and is also blood thinning. It should not be taken if you're on any medicine to thin your blood."
Alpha lipoic acid
Alpha lipoic acid may safeguard the beta-cells in your pancreas which are vital for insulin production.
Grayson adds it could also help your blood sugar reach these cells to reduce insulin resistance, improve blood glucose control and minimise your likelihood of diabetes complications.
Grayson says: "Alpha lipoic acid can cause hypoglycaemia, is blood thinning and can affect thyroid hormone levels."
Gymnema
Research suggests that Gymnema can hinder sugar cravings, lower high blood sugar levels, and support weight loss.
Grayson says: "Gymnema may cause hypoglycaemia and also may interfere with how your liver breaks down medicine. Check with a healthcare professional to make sure your medicine will not be affected."
Chromium
Chromium may boost insulin sensitivity and help maintain blood sugar control.
Grayson says: "Chromium is relatively safe to take in dosages of 100-200 micrograms."
Other treatments for diabetes
Torna ai contenutiMedicina
Le persone con diabete di tipo 1 need to take insulin - either through injections or an insulin pump. This helps manage blood sugar levels and reduces your chance of serious short and long-term complications.
Le persone con diabete di tipo 2 will be encouraged to adopt healthier lifestyle changes. If this is not enough, medicine will be recommended.
Grayson highlights some of the most commonly prescribed treatments:
Metformina - slows glucose absorption, reduces liver glucose production, and improves insulin sensitivity.
Sulfonylureas - the most common drug in this class is gliclazide, which boosts insulin production and release from the pancreas, with hypoglycaemia as a potential side effect.
DPP-4 inhibitors - include sitagliptin e linagliptin, which increase insulin and reduce liver glucose production in response to high blood sugar.
SGLT2 Inhibitors - also known as gliflozins, such as dapagliflozin, these drugs help remove excess glucose through your pee, and may reduce the chance of kidney damage in type 2 diabetes.
GLP-1 analogues - medicines such as semaglutide e dulaglutide mimic a natural protein that helps the body control blood sugar. GLP-1 analogues are usually given by injection.
A healthy diet
Diabetes UK says that by eating a balanced diet, most people can get all the nutrients they need without extra dietary supplements.
Grayson agrees that healthy eating is vital for keeping your body running smoothly - especially if you have diabetes.
"When thinking about diet with diabetes, it is important to minimise your chance of a spike in blood sugar by choosing complex carbohydrates," she advises. "Opt for whole grains instead of pasta, rice, bread and cakes which are full of simple starches that cause blood sugar to rise quickly.
Eating a balanced proportion of complex carbohydrates with sufficient protein and healthy fats helps keep blood sugar stable longer and increases fullness.
"If you have a sweet treat, then make sure it is at the same time as a well-balanced meal to minimise the impact on your glucose levels," Grayson recommends. "Limit your number of treats to one or two a week."
Regular exercise
Regular exercise also helps improve insulin sensitivity and stabilise your blood sugar.
Grayson says: "A 30-minute walk a day can help get your blood sugar under control. Combining this with better-balanced meals can also support weight management to reduce your chance of diabetes complications."
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Storia dell'articolo
Le informazioni su questa pagina sono revisionate da clinici qualificati.
Next review due: 4 Dec 2027
4 Dec 2024 | Pubblicato originariamente
Autore:
Victoria RawRevisione paritaria di
Michael Stewart, MRPharmS

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