Fenobarbital per l'epilessia
Revisione paritaria di Sid DajaniUltimo aggiornamento di Michael Stewart, MRPharmSUltimo aggiornamento 5 May 2025
Rispetta le linee guida editoriali
- ScaricaScarica
- Condividi
- Language
- Discussione
- Versione audio
- Aggiungi alle fonti preferite su Google
You need to take phenobarbital regularly every day. Take your dose at bedtime.
Phenobarbital may cause you to feel drowsy and unsteady. This often settles down as your body adjusts to the new medicine.
Do not drink alcohol.
A colpo d'occhio
Phenobarbital is an anti-epileptic medicine used to prevent seizures.
It works by stabilising the electrical activity in your brain.
Take phenobarbital exactly as your doctor tells you, usually once a day at bedtime.
Do not stop taking this medicine suddenly, as this could cause seizures to return.
Avoid alcohol and discuss contraception with your doctor, as phenobarbital can interfere with it.
Tell your doctor if you experience a high temperature, severe skin rash, or yellow skin/eyes.
About phenobarbital
Tipo di medicinale | Un medicinale antiepilettico |
Utilizzato per | Epilessia |
Disponibile come | Tablets, oral liquid and injection |
Se hai epilessia, it means that you have had more than one unexplained fit, or seizure. A seizure is a short episode of symptoms caused by a burst of abnormal electrical activity in your brain. Different parts of the brain control different functions of your body, so the symptoms that occur during a seizure will depend on where the abnormal burst of electrical activity occurs. Symptoms that may occur during a seizure can affect your muscles, sensations, behaviour, emotions, consciousness, or a combination of these. The seizures can be prevented in most people by suitable anti-epileptic medication.
Phenobarbital works by stabilising the electrical activity of your brain, which helps to prevent the seizures from occurring.
Before taking phenobarbital
Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking phenobarbital it is important that your doctor knows:
Se sei incinta, stai cercando di avere un bambino o stai allattando.
Se hai problemi respiratori.
If you have ever had problems with drug or alcohol dependence.
Se hai problemi con il funzionamento dei tuoi reni o del tuo fegato.
Se hai un raro disturbo ereditario del sangue chiamato porfiria.
Se stai assumendo altri medicinali. Questo include qualsiasi medicinale disponibile per l'acquisto senza prescrizione, così come i medicinali a base di erbe e complementari.
Se hai mai avuto una reazione allergica a un medicinale.
How to take phenobarbital
Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about phenobarbital and will provide you with a full list of the side-effects which you may experience from taking it.
Take phenobarbital exactly as your doctor tells you to. It is usual to take one dose a day, at bedtime. Your doctor will tell you how many tablets to take for the dose. This information will also be printed on the label of the pack to remind you about what the doctor said to you. You need to take phenobarbital regularly every day to prevent the fits (seizures) from occurring.
Try to take your doses of phenobarbital at the same time each evening. Having a routine like this will help you to remember to take your doses regularly. Swallow the phenobarbital tablets with a drink of water. You can take them either with or without food.
Se dimentichi di prendere una dose, prendila appena te ne ricordi, a meno che non sia quasi ora della dose successiva, in tal caso salta la dose dimenticata. Non prendere due dosi insieme per compensare una dose dimenticata.
Ottenere il massimo dal tuo trattamento
Cerca di mantenere i tuoi appuntamenti regolari con il tuo medico. Questo è per permettere al tuo medico di controllare i tuoi progressi. Potresti aver bisogno di fare esami del sangue di tanto in tanto.
When you first start a new treatment for epilepsy there may be a change in the number or type of fits (seizures) you experience. Your doctor will advise you about this.
Phenobarbital made by different manufacturers can act in a slightly different way in your body. Because of this, it is recommended that you continue to take tablets/medicine from the same manufacturer as you have had before. So, each time you collect a prescription, check to make sure your supply looks the same. If you are unsure, or if have any questions about your prescription, please ask your pharmacist to check it for you.
Durante il trattamento per l'epilessia, c'è un piccolo rischio di sviluppare cambiamenti d'umore, pensieri angoscianti e sentimenti di suicidio. Se ciò accade, devi informare immediatamente il tuo medico.
People with epilepsy must stop driving at first. Your doctor will advise you about when it may be possible for you to resume driving again. This will usually be after a year free of seizures.
Do not stop taking this medicine unless your doctor tells you to do so. Stopping it suddenly can cause your seizures to return and your doctor will want you to reduce your dose gradually if this becomes necessary. Also, taking phenobarbital over a time can lead to your body becoming dependent on it and this is another reason why your doctor will want to reduce your dose slowly.
You are advised not to drink alcohol while you are taking phenobarbital. Phenobarbital will make you feel sleepy and drinking alcohol will increase this. Some liquid medicines may contain noticeable amounts of alcohol, read the manufacturer's leaflet for more information.
If you are due to have an operation or any dental treatment, please tell the person carrying out the treatment that you are taking phenobarbital.
If you buy any medicines, check with a pharmacist that they are suitable for you to take alongside phenobarbital.
You should avoid becoming pregnant while you are taking phenobarbital because it could cause harm to your unborn baby.
If you are a woman using hormonal contraception ('the pill' or the 'mini pill'), discuss this with your doctor, as phenobarbital interferes with these and could mean you are more likely to become pregnant. Other methods of contraception will be more suitable for you.
If you want to have a family, make sure you discuss this with your doctor well in advance of becoming pregnant. This is so that you can be given advice from a specialist before you become pregnant. If you become pregnant while you are taking phenobarbital, you should tell your doctor straightaway.
Can phenobarbital cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with phenobarbital. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Common phenobarbital side-effects | Cosa posso fare se sperimento questo? |
Feeling unsteady | Getting up or moving more slowly should help. If this continues, let your doctor know |
Sensazione di sonnolenza o stanchezza | Make sure your reactions are normal before you use tools or machines |
Feeling short of breath, behavioural changes, mood changes (such as feeling irritable, confused, excited or depressed), impaired memory | Se uno di questi diventa problematico, parla con il tuo medico |
Importante: your doctor will have discussed with you the possibility of some less common but more serious side-effects. Let your doctor know straightaway if you experience any of the following:
A high temperature (fever) and swollen glands.
A severe skin rash.
Yellowing of your skin or the whites of your eyes (jaundice).
Se si verificano altri sintomi che ritieni possano essere dovuti al medicinale, parla con il tuo medico o farmacista per ulteriori consigli.
How to store phenobarbital
Tenere tutti i medicinali fuori dalla portata e dalla vista dei bambini.
Conservare in un luogo fresco e asciutto, lontano da fonti di calore e luce diretta.
Liquid medicines should be used within 28 days of opening, unless otherwise stated on the bottle.
Informazioni importanti su tutti i medicinali
Informazioni importanti su tutti i medicinali
Non assumere mai più della dose prescritta. Se sospetti che tu o qualcun altro possa aver assunto un sovradosaggio di questo medicinale, recati immediatamente al pronto soccorso del tuo ospedale locale. Porta con te il contenitore, anche se è vuoto.
Questo medicinale è per te. Non darlo mai ad altre persone, anche se la loro condizione sembra essere la stessa della tua.
Non conservare medicinali scaduti o indesiderati. Portali alla tua farmacia locale che li smaltirà per te.
Se hai domande su questo medicinale, chiedi al tuo farmacista.
Segnala effetti collaterali di un medicinale o vaccino
Se si verificano effetti collaterali, è possibile segnalarli online tramite il Sito web Yellow Card.

Non sei sicuro di mescolare i medicinali?
Controlla le possibili interazioni tra farmaci, integratori e alimenti prima di assumerli insieme.
Domande frequenti
What is epilepsy and why do I need phenobarbital?
Epilepsy means you've had more than one unexplained fit or seizure. Seizures are caused by abnormal electrical activity in your brain. Phenobarbital helps to prevent these seizures by stabilising your brain's electrical activity.
Can I drive while taking phenobarbital?
Initially, you must stop driving. Your doctor will advise you on when it's safe to resume, usually after a year without any seizures.
Are there any specific situations where I should inform a healthcare professional that I'm taking phenobarbital?
Yes, you should always tell the person carrying out treatment that you are taking phenobarbital if you are due to have an operation or any dental treatment. Also, if you buy any other medicines, check with a pharmacist to ensure they are suitable to take alongside phenobarbital.
Should I be concerned about my mood or thoughts while on phenobarbital?
While being treated for epilepsy, there's a small risk of developing mood changes, distressing thoughts, or feelings about suicide. If this happens, you must tell your doctor straightaway.
What should I do if I get my phenobarbital from a different manufacturer?
Phenobarbital from different manufacturers can act slightly differently in your body. It's recommended to continue taking medicine from the same manufacturer. Always check your supply each time you collect a prescription, and if you're unsure, ask your pharmacist.
What should I do if I notice yellowing of my skin or eyes, or a severe skin rash?
These are less common but more serious side-effects. You should let your doctor know straightaway if you experience yellowing of your skin or the whites of your eyes (jaundice) or a severe skin rash.
Ulteriori letture e riferimenti
- Manufacturer's PIL, Phenobarbital Thornton & Ross 15mg/5ml Elixir; Thornton & Ross Ltd, The electronic Medicines Compendium. Dated September 2020.
- Medicinali Completi BNF 89ª Edizione; Associazione Medica Britannica e Società Farmaceutica Reale di Gran Bretagna, Londra.
Informazioni sull'autoreVisualizza il profilo completo

Michael Stewart, MRPharmS
Responsabile Revisione Foglietti Illustrativi – Contrattista, Farmacista
BPharm (Hons), MRPharmS
Michael è un farmacista comunitario che esercita nelle Midlands e nel South Yorkshire con oltre 20 anni di esperienza nel consigliare su farmaci e condizioni mediche. Ha una solida esperienza nella formazione sanitaria, avendo prodotto e tenuto corsi di formazione per team di farmacia e personale di strutture di assistenza residenziale, inclusi infermieri. Ha anche contribuito a consigli consultivi farmaceutici per la gestione di condizioni a bassa gravità nella comunità.
Informazioni sul recensore

Sid Dajani
Sultan Dajani si è laureato alla London School of Pharmacy nel 1994 ed è diventato il più giovane membro eletto del consiglio della Royal Pharmaceutical Society dalla sua fondazione nel 1842.
Storia dell'articolo
Le informazioni su questa pagina sono scritte e revisionate da clinici qualificati.
Articolo disponibile anche in Inglese, Tedesco, Spagnolo, Francese, Italiano, Portoghese, Hindi, Ebraico, Arabo, and Svedese.
Next review due: 5 May 2028
5 May 2025 | Ultima versione

Chiedi, condividi, connettiti.
Esplora le discussioni, fai domande e condividi esperienze su centinaia di argomenti di salute.
Iscriviti alla newsletter di Patient
La tua dose settimanale di consigli sulla salute chiari e affidabili - scritti per aiutarti a sentirti informato, sicuro e in controllo.
Abbonandoti accetti i nostri Informativa sulla Privacy. Puoi annullare l'iscrizione in qualsiasi momento. Non vendiamo mai i tuoi dati.
Altri farmaci del sistema nervoso
- Tossina botulinica di tipo A per emicrania
- Buspirone per ansia
- Carbamazepina per l'epilessia
- Clomipramina
- Diazepam - una benzodiazepina
- Entacapone per la malattia di Parkinson
- Fluoxetina
- Iniezione a lunga durata di aloperidolo
- Compresse e medicina liquida di imipramina
- Lamotrigina per epilessia
- Levetiracetam per l'epilessia
- Compresse di melatonina per l'insonnia
- Compresse di Modafinil
- Neostigmina per miastenia grave
- Orphenadrine
- Paroxetina
- Risperidone
- Compresse di ropinirolo
- Sertralina
- Venlafaxina