Iniezione a lunga durata di flupentixolo
Depixol, Psytixol
Revisione paritaria di Sid DajaniUltimo aggiornamento di Michael Stewart, MRPharmSUltimo aggiornamento 23 Nov 2022
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Flupentixol long-acting injection will be given to you by your clinic doctor or nurse every 2-4 weeks.
If you miss an appointment for an injection, make another appointment as soon as possible.
There are a number of side-effects which you could experience from the treatment. If you are concerned about any, you should discuss them with your doctor.
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About flupentixol long-acting injection
Tipo di medicinale | An antipsychotic injection |
Utilizzato per | Maintainance of symptoms in adults with schizophrenia and other similar mental health problems |
Chiamato anche | Flupentixol decanoate: Depixol®; Psytixol® |
Disponibile come | Long-acting 'depot' injection |
Flupentixol belongs to a group of medicines called antipsychotics. You will have been prescribed it to maintain symptom control of schizofrenia.
Schizophrenia is a mental health condition that causes disordered ideas, beliefs and experiences. Symptoms of schizophrenia include hearing, seeing, or sensing things that are not real, having mistaken beliefs, feeling unusually suspicious, and becoming withdrawn. Flupentixol is used to relieve the symptoms of schizophrenia and other similar mental health problems. It works on the balance of chemical substances in your brain.
Long-acting, or 'depot', injections are used once your symptoms have been eased by taking tablets. The injection slowly releases flupentixol into your body and is given every 2-4 weeks. The main advantage of a depot injection is that you do not have to remember to take tablets every day.
Before having flupentixol long-acting injection
Torna ai contenutiSome medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start having flupentixol long-acting injections, it is important that your doctor knows:
Se sei incinta o stai allattando.
Se hai una malattia cardiaca o dei vasi sanguigni.
Se hai problemi con il funzionamento del tuo fegato, o se hai problemi con il funzionamento dei tuoi reni.
Se hai problemi alla prostata.
Se hai problemi con la respirazione.
If you have any of the following: epilepsy, diabetes (diabetes mellitus), depression, Parkinson's disease, raised pressure in your eye (glaucoma), thyroid problems, or a condition which causes muscle weakness, called myasthenia gravis.
If you have ever had yellowing of your skin or the whites of your eyes (jaundice).
If you have a blood disorder, particularly if you have the rare inherited blood disorder called porphyria.
Se hai un tumore alla ghiandola surrenale (una condizione chiamata feocromocitoma).
Se hai avuto una reazione allergica a un medicinale.
Se stai assumendo o utilizzando altri medicinali. Questo include qualsiasi medicinale che stai assumendo e che è disponibile per l'acquisto senza prescrizione, così come i medicinali a base di erbe e complementari.
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How flupentixol long-acting injection is given
Torna ai contenutiBefore you start the treatment, ask to read the manufacturer's printed information leaflet from inside the pack. The leaflet will give you more information about flupentixol, and it will also provide you with a full list of the side-effects which you could experience.
Flupentixol long-acting injection will be given to you by a doctor or nurse. If you haven't received an injection like flupentixol before, a small dose is usually given as a test one week before you have a full dose. This is to see how well you tolerate the injection. The injection is given into a muscle in your bottom (buttocks) or upper leg.
You may be asked to continue taking your tablets for a short while after you have had your first injection. This is because it can take a few weeks before you feel the full effect from the injection.
Treatment with flupentixol is usually long-term so that your symptoms don't return.
Ottenere il massimo dal tuo trattamento
Torna ai contenutiYour treatment will require careful monitoring to make sure that you get the best possible benefit from flupentixol. Keep your regular doctor's appointments so that you get your injections on time, and your progress can be checked. If you miss an appointment for an injection, contact your doctor to arrange for another appointment as soon as possible.
Flupentixol could cause your skin to become more sensitive to sunlight than normal. Avoid strong sunlight and sunbeds, and use a sun cream with a high sun protection factor even on bright but cloudy days.
If you drink alcohol, ask your doctor for advice about drinking while you are on flupentixol. Alcohol can increase the chance that you experience side-effects and may not be recommended for you.
If you have diabetes you may need to check your blood sugar (glucose) more frequently, as flupentixol can affect the levels of sugar in your blood. Your doctor will advise you about this.
If you are having any dental treatment or an operation, tell the person carrying out the treatment that you have had a flupentixol injection. This is important because it may interfere with the anaesthetic you receive.
If you buy or take any 'over-the-counter' medicines, check with a pharmacist that they are suitable for you to take with flupentixol.
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Can flupentixol long-acting injection cause problems?
Torna ai contenutiAlong with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the more common ones associated with flupentixol. The best place to find a full list of the side-effects which can be associated with your medicine, is from the manufacturer's printed information leaflet supplied with the medicine. Alternatively, you can find an example of a manufacturer's information leaflet in the reference section below. Speak with your doctor or pharmacist if any of the following continue or become troublesome.
Very common flupentixol side-effects (these affect more than 1 in 10 people) | Cosa posso fare se sperimento questo? |
Sensazione di sonnolenza | Non guidare e non utilizzare strumenti o macchinari mentre sei sotto effetto |
Feeling restless, movement problems | Speak with your doctor |
Bocca secca | Prova a masticare gomme senza zucchero o a succhiare caramelle senza zucchero |
Common flupentixol side-effects (these affect fewer than 1 in 10 people) | Cosa posso fare se sperimento questo? |
Pain at the site of the injection | This should not last long. If the area becomes red, swollen or 'lumpy', let your doctor know |
Feeling dizzy or tired, blurred vision | Non guidare e non utilizzare strumenti o macchinari mentre sei sotto effetto |
Mal di testa | Bevi molta acqua e chiedi al tuo farmacista di consigliarti un antidolorifico adatto. Se i mal di testa persistono, consulta il tuo medico |
Unusual or uncontrollable muscle movements, feeling shaky | Parla con il tuo medico di questi |
Increased appetite and weight, difficulty sleeping, feeling agitated or confused, mood changes (such as feeling depressed), reduced interest in sex, loss of concentration, feeling short of breath, producing more saliva than usual, fast heartbeats, stomach upset, feeling sweaty, muscle aches, and difficulty passing urine | Discuti questi con il tuo medico se qualcuno diventa problematico |
Importante: if you experience symptoms such as muscle stiffness, a very high temperature, feeling confused or sweaty, a fast heartbeat, and urinary incontinence, you should contact your doctor immediately. These can be signs of a rare but serious condition known as neuroleptic malignant syndrome.
If you experience any other symptoms which you think may be due to the injection, speak with your doctor or pharmacist for further advice.
How to store flupentixol long-acting injection
Torna ai contenutiTenere tutti i medicinali fuori dalla portata e dalla vista dei bambini.
Conservare in un luogo fresco e asciutto, lontano da fonti di calore e luce diretta.
Informazioni importanti su tutti i medicinali
Torna ai contenutiInformazioni importanti su tutti i medicinali
If you suspect that you have had an overdose of this medicine, go to the accident and emergency department of your local hospital at once.
Questo medicinale è per te. Non darlo mai ad altre persone, anche se la loro condizione sembra essere la stessa della tua.
Non conservare medicinali scaduti o indesiderati. Portali alla tua farmacia locale che li smaltirà per te.
Se hai domande su questo medicinale, chiedi al tuo farmacista.
Segnala effetti collaterali di un medicinale o vaccino
Se si verificano effetti collaterali, è possibile segnalarli online tramite il Yellow Card website.

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Ulteriori letture e riferimenti
- Manufacturer's PIL, Depixol® 20 mg/ml solution for injection; Lundbeck Limited, Il compendio elettronico dei medicinali. Datato gennaio 2021.
- Medicinali Completi BNF 89ª Edizione; Associazione Medica Britannica e Società Farmaceutica Reale di Gran Bretagna, Londra.
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About the author

Michael Stewart, MRPharmS
Medicine Leaflet Review Manager – Contractor, Pharmacist
BPharm (Hons), MRPharmS
Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.
About the reviewer

Sid Dajani
Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.
Storia dell'articolo
Le informazioni su questa pagina sono scritte e revisionate da clinici qualificati.
Prossima revisione prevista: 22 maggio 2027
23 Nov 2022 | Ultima versione

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