Modafinil tablets
Provigil
Revisione paritaria di Sid DajaniUltimo aggiornamento di Michael Stewart, MRPharmSUltimo aggiornamento 14 Ago 2023
Rispetta le linee guida editoriali
- ScaricaScarica
- Condividi
- Language
- Discussione
- Versione audio
- Aggiungi alle fonti preferite su Google
Take modafinil at the same times each day to avoid missing any doses.
The most common side-effects include headache, feeling sick (nausea) and feeling dizzy.
You should not become pregnant whilst taking modafinil. Ask your doctor about which contraceptive methods are suitable for you while you are taking modafinil - hormonal contraceptives are not suitable.
A colpo d'occhio
Modafinil is a central nervous system stimulant used for daytime sleepiness due to narcolepsy.
It helps to control narcolepsy symptoms by increasing alertness and reducing sleepiness.
Take modafinil exactly as prescribed by your doctor, usually as a 200 mg daily dose.
Do not use modafinil if you are pregnant or trying for a baby.
Hormonal contraceptives are less effective when used with modafinil; discuss other options with your doctor.
Common side-effects include headache, dry mouth, and feeling sick.
See a doctor immediately if you develop a rash, mood changes, or thoughts of harming yourself.
In questo articolo:
Scelte video per Farmaci per il sistema nervoso
Continua a leggere sotto
About modafinil
Tipo di medicinale | A central nervous system stimulant |
Utilizzato per | Daytime sleepiness associated with narcolepsy in adults |
Chiamato anche | Provigil® |
Disponibile come | Compresse |
Narcolessia is a long-term problem that affects your sleep. You feel excessively tired during the daytime but have disturbed night-time sleep. You can also have sleep attacks where you fall asleep at inappropriate times during the day without any warning.
Although there is no cure for narcolepsy, modafinil can help to control your symptoms. Modafinil works by stimulating the central nervous system to increase your alertness and reduce excessive sleepiness during the day.
Before taking modafinil
Torna ai contenutiSome medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking modafinil it is important that your doctor knows:
Se sei incinta, stai cercando di avere un bambino o stai allattando.
Se hai problemi con il funzionamento del fegato o dei reni.
If you have a heart condition or high blood pressure (hypertension).
If you have ever had a mental health problem such as depression, psychosis or mania.
Se hai mai avuto problemi con l'abuso di droghe o alcol.
Se stai assumendo altri medicinali. Questo include qualsiasi medicinale che stai assumendo e che è disponibile per l'acquisto senza prescrizione medica, così come i medicinali a base di erbe e complementari.
Se hai mai avuto una reazione allergica a un medicinale.
Nota dell'autore clinico Michael Stewart 01/03/2020: Based on post-marketing reports from the USA, modafinil (Provigil®) may harm an unborn child. Modafinil should not be used during pregnancy. Women of childbearing potential must use effective contraception during treatment with modafinil and for two months after stopping. Discuss with your doctor which forms of contraception are suitable for you, as hormonal contraceptives are made less effective by modafinil. Alternative treatment options for narcolepsy should be used during pregnancy, such as behaviour modifications, good sleeping habits and scheduled daytime naps.
Continua a leggere sotto
How to take modafinil
Torna ai contenutiBefore you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about modafinil and will provide you with a full list of the side-effects which you may experience from taking it.
Take the tablets exactly as your doctor tells you to. There are two strengths of tablet available - 100 mg and 200 mg. When you first start modafinil it is usual to be prescribed a dose of 200 mg daily. You may be asked to take this as a single dose of 200 mg in the morning, or divided into 100 mg in the morning and 100 mg at midday. Your doctor or pharmacist will tell you which is right for you. Your dose may be increased after a little while, depending upon your symptoms.
Take your doses with a drink of water to help you swallow the tablet. Do not break or crush the tablet - it should be swallowed whole. You can take modafinil before or after food.
If you forget to take a dose, miss out the forgotten dose completely but make sure that you remember to take your next dose when it is due. Do not take two doses together to make up for a forgotten dose.
Ottenere il massimo dal tuo trattamento
Torna ai contenutiKeep your regular appointments with your doctor so that your progress can be monitored. You may need to have your blood pressure and heart rate checked regularly.
Modafinil can cause blurred vision or dizziness in some people and therefore it may affect your ability to use tools or machines, so take care when using them. Sleepiness associated with your condition can add to this.
Taking modafinil is not a replacement for a good sleep routine. It is still important that you aim to get around eight hours of sleep at night if possible. You should try to go to sleep and get up at about the same time each day.
In the UK, you are required by law to let the Driver and Vehicle Licensing Authority (DVLA) know if you are diagnosed with narcolepsy. You may be allowed to drive again when your symptoms are well controlled with medication, but you will need to have regular reviews. Your doctor will advise you about this.
Modafinil should not be used during pregnancy. Women of childbearing potential must use effective contraception during treatment with modafinil and for two months after stopping.
Hormonal contraceptives, including oral contraceptive pills, implants, intrauterine contraceptive devices (IUCDs) and contraceptive patches, are less effective when used with modafinil and are therefore not recommended. Speak to your doctor about which contraceptive methods are suitable for you while you are taking modafinil.
If you are planning to become pregnant you should stop taking modafinil and try alternative treatment options such as good sleep habits and scheduled daytime naps.
If you are having an operation or dental treatment, tell the person carrying out the treatment that you are taking modafinil.
Continua a leggere sotto
Can modafinil cause problems?
Torna ai contenutiAlong with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with modafinil. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Common modafinil side-effects | Cosa posso fare se sperimento questo? |
Mal di testa | This usually passes within a day or so, but in the meantime, ask your pharmacist to recommend a suitable painkiller. If the headache continues, speak with your doctor |
Bocca secca | Prova a masticare gomme senza zucchero o a succhiare caramelle senza zucchero |
Feeling sick (nausea), indigestion, stomach ache | Attieniti a pasti semplici - evita cibi ricchi o piccanti |
Diarrea | Bevi molta acqua per reintegrare i liquidi persi |
Costipazione | Cerca di seguire una dieta equilibrata e bevi diversi bicchieri d'acqua ogni giorno |
Feeling dizzy or tired, blurred vision | Take special care when using tools or machines |
Flushing, loss of appetite, nervousness, difficulty sleeping, anxiety, depression, confusion or confused thinking, chest pain, fast heartbeat, numbness or tingling feelings | Speak with your doctor if any of these continue or become troublesome |
Importante: if you experience any of the following symptoms, stop taking modafinil and contact your doctor for advice immediatamente:
A rash or blisters on the skin.
Any changes to your mood, behaviour, or thinking.
Any suicidal thoughts, or thoughts about harming yourself.
Se si verificano altri sintomi che ritieni possano essere dovuti alle compresse, parla con il tuo medico o farmacista per ulteriori consigli.
How to store modafinil
Torna ai contenutiTenere tutti i medicinali fuori dalla portata e dalla vista dei bambini.
Conservare in un luogo fresco e asciutto, lontano da fonti di calore e luce diretta.
Informazioni importanti su tutti i medicinali
Torna ai contenutiInformazioni importanti su tutti i medicinali
Non assumere mai più della dose prescritta. Se sospetti che tu o qualcun altro possa aver assunto un sovradosaggio di questo medicinale, recati immediatamente al pronto soccorso del tuo ospedale locale. Porta con te il contenitore, anche se è vuoto.
Questo medicinale è per te. Non darlo mai ad altre persone, anche se la loro condizione sembra essere la stessa della tua.
Se acquisti dei medicinali, verifica con un farmacista che siano adatti da assumere insieme agli altri tuoi medicinali.
Non conservare medicinali scaduti o indesiderati. Portali alla tua farmacia locale che li smaltirà per te.
Se hai domande su questo medicinale, chiedi al tuo farmacista.
Segnala effetti collaterali di un medicinale o vaccino
Se si verificano effetti collaterali, è possibile segnalarli online tramite il Sito web Yellow Card.

Non sei sicuro di mescolare i medicinali?
Controlla le possibili interazioni tra farmaci, integratori e alimenti prima di assumerli insieme.
Domande frequenti
What is narcolepsy and how does modafinil help?
Narcolepsy is a long-term condition that causes excessive tiredness during the day and disturbed sleep at night. People with narcolepsy can also have 'sleep attacks' where they fall asleep suddenly without warning. Modafinil helps by stimulating the central nervous system to increase alertness and reduce this excessive daytime sleepiness.
Can I take modafinil if I have other health problems?
You should tell your doctor if you have any existing health problems before starting modafinil. This includes issues with your liver or kidneys, heart conditions, high blood pressure, or any history of mental health problems like depression or psychosis. It's also important to mention if you have had drug or alcohol misuse, or any allergies to medicines.
How should I take my modafinil dose?
You should take your modafinil tablets exactly as prescribed by your doctor. They come in 100 mg and 200 mg strengths. Usually, you start with a 200 mg daily dose, which might be taken as one tablet in the morning or divided into 100 mg in the morning and 100 mg at midday. Always swallow the tablet whole with water; do not break or crush it. It can be taken with or without food.
What if I forget to take a dose of modafinil?
If you forget to take a dose, you should miss out that forgotten dose completely. Do not try to take two doses together to catch up. Simply take your next scheduled dose when it is due.
Are there any activities I should be careful with while taking modafinil?
Modafinil can cause blurred vision or dizziness in some individuals. This, combined with the underlying sleepiness from narcolepsy, means you should be cautious when using tools or operating machinery. If you drive, you must inform the DVLA about your narcolepsy, and your doctor will advise you about driving safely once your symptoms are well controlled.
Can modafinil affect contraception?
Yes, modafinil can make hormonal contraceptives, such as oral contraceptive pills, implants, IUCDs, and patches, less effective. These methods are generally not recommended when taking modafinil. Women of childbearing potential must use effective contraception during treatment and for two months after stopping. You should discuss suitable contraceptive methods with your doctor.
What should I do if I experience side-effects from modafinil?
Many common side-effects, like headache or dry mouth, often improve as your body adjusts. For a headache, a suitable painkiller from your pharmacist might help. For a dry mouth, try sugar-free gum or sweets. However, if any side-effects continue or become troublesome, you should speak with your doctor or pharmacist. It's crucial to stop modafinil and contact your doctor immediately if you develop a rash or blisters, notice any changes in mood, behaviour, or thinking, or experience suicidal thoughts.
Ulteriori letture e riferimenti
- Manufacturer's PIL, Modafinil (Provigil®) 100 mg and 200 mg tablets; Teva Pharma B.V., The electronic Medicines Compendium. Dated October 2021.
- Medicinali Completi BNF 89ª Edizione; Associazione Medica Britannica e Società Farmaceutica Reale di Gran Bretagna, Londra.
Continua a leggere sotto
Informazioni sull'autoreVisualizza il profilo completo

Michael Stewart, MRPharmS
Responsabile Revisione Foglietti Illustrativi – Contrattista, Farmacista
BPharm (Hons), MRPharmS
Michael è un farmacista comunitario che esercita nelle Midlands e nel South Yorkshire con oltre 20 anni di esperienza nel consigliare su farmaci e condizioni mediche. Ha una solida esperienza nella formazione sanitaria, avendo prodotto e tenuto corsi di formazione per team di farmacia e personale di strutture di assistenza residenziale, inclusi infermieri. Ha anche contribuito a consigli consultivi farmaceutici per la gestione di condizioni a bassa gravità nella comunità.
Informazioni sul recensore

Sid Dajani
Sultan Dajani si è laureato alla London School of Pharmacy nel 1994 ed è diventato il più giovane membro eletto del consiglio della Royal Pharmaceutical Society dalla sua fondazione nel 1842.
Storia dell'articolo
Le informazioni su questa pagina sono scritte e revisionate da clinici qualificati.
Prossima revisione prevista: 13 Ago 2026
14 Ago 2023 | Ultima versione

Chiedi, condividi, connettiti.
Esplora le discussioni, fai domande e condividi esperienze su centinaia di argomenti di salute.
Iscriviti alla newsletter di Patient
La tua dose settimanale di consigli sulla salute chiari e affidabili - scritti per aiutarti a sentirti informato, sicuro e in controllo.
Abbonandoti accetti i nostri Informativa sulla Privacy. Puoi annullare l'iscrizione in qualsiasi momento. Non vendiamo mai i tuoi dati.