Primidone for epilepsy
Enodama
Revisione paritaria di Sid DajaniUltimo aggiornamento di Michael Stewart, MRPharmSUltimo aggiornamento 5 Apr 2025
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You need to take primidone regularly to prevent seizures from occurring. It is usually taken twice daily.
It may cause you to feel drowsy.
Do not drink alcohol.
Do not suddenly stop taking it as this is likely to make your fits return.
In questo articolo:
About primidone
Tipo di medicinale | Anti-epileptic |
Utilizzato per | Epilessia |
Chiamato anche | Enodama®, Liskantin®, Mysoline® |
Disponibile come | Tablets, oral liquid medicine |
Se hai epilessia, it means that you have had repeated fits (seizures). A seizure is a short episode of symptoms caused by a burst of abnormal electrical activity in your brain. Different parts of the brain control different parts and functions of your body. Therefore, the symptoms that occur during a seizure depend on where the abnormal burst of electrical activity occurs. Symptoms that may occur during a seizure can affect your muscles, sensations, behaviour, emotions, consciousness, or a combination of these.
Epilepsy cannot be 'cured', but the seizures can be prevented in most people by suitable anti-epileptic medication. Primidone helps prevent seizures from occurring.
Before taking primidone
Torna ai contenutiSome medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking primidone it is important that your doctor or pharmacist knows:
Se sei incinta, stai cercando di avere un bambino o stai allattando.
Se hai problemi respiratori.
If you have ever had problems with drug or alcohol dependence.
If you have liver or kidney problems.
If you have a rare inherited blood disorder known as porphyria.
If you are taking or using any other medicines. This includes any medicines which are available to buy without a prescription, as well as herbal and complementary medicines.
Se hai mai avuto una reazione allergica a un medicinale.
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How to take primidone
Torna ai contenutiBefore you start this treatment, read the manufacturer's printed information leaflet from inside the pack. The leaflet will give you more information about primidone and a full list of side-effects which you may experience from taking it.
Take primidone exactly as your doctor has told you. It is usually taken twice a day, although to begin with you will be prescribed a small dose to take at bedtime. This will then be increased gradually. Increasing your dose slowly allows your doctor to make sure that you have the dose that best suits you, but avoids any unwanted symptoms. Your dose will be on the label of your pack to remind you how to take the tablets. You need to take primidone regularly to prevent the fits (seizures) from occurring.
You can take the tablets before or after food. You may find it helps to swallow them with a drink of water.
If you forget to take a dose, take it as soon as you remember. If it is almost time to take your next dose, skip the missed dose and take your next dose when it is due. Do not take two doses together to make up for a forgotten dose.
Ottenere il massimo dal tuo trattamento
Torna ai contenutiCerca di mantenere i tuoi appuntamenti regolari con il tuo medico. Questo è per permettere al tuo medico di controllare i tuoi progressi.
When you first start a new treatment for epilepsy there may be a change in the number or type of fits (seizures) you experience. Your doctor will advise you about this.
Different brands of primidone may act in a slightly different way in your body. Because of this your pharmacist will always try to give you tablets from the same manufacturer as you have had before. So, each time you collect a prescription, check to make sure your supply looks the same and that the brand name is the same. If you are unsure, or if you have any questions about your prescription, please ask your pharmacist to check it for you.
People with epilepsy must stop driving at first. Your doctor will advise you about when it may be possible for you to resume driving again. This will usually be after a year free of seizures.
Do not stop taking this medicine unless your doctor tells you to do so. Stopping it suddenly can cause your seizures to return and your doctor will want you to reduce your dose gradually if this is necessary. Also, taking primidone over a time may lead to your body becoming dependent on it and this is another reason why your doctor will want to reduce your dose slowly.
Emotional stress or a lack of sleep could make you more likely to have a seizure. Keeping to a regular sleep pattern and using relaxation exercises can reduce this risk. Speak with your doctor or pharmacist for advice.
If you are having an operation or dental treatment, tell the person carrying out the treatment that you are taking primidone.
If you buy any medicines, check with a pharmacist that they are suitable for you to take alongside primidone.
If you are a woman using hormonal contraception ('the pill'), discuss this with your doctor as primidone interferes with the pill, reducing its contraceptive effect. Other methods of contraception will be more suitable for you. If you want to have a family, make sure you discuss this with your doctor well in advance of becoming pregnant. This is so that you can be given advice from a specialist before you become pregnant. If you become pregnant while you are taking primidone, you should tell your doctor straightaway.
You are advised not to drink alcohol while you are on primidone. Primidone will make you feel sleepy and drinking alcohol will increase this.
While you are taking these tablets, there is a small risk that you may develop mood changes or distressing feelings, and thoughts about suicide. If this happens, you must tell your doctor straightaway.
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Can primidone cause problems?
Torna ai contenutiAlong with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. These usually improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following side-effects continue or become troublesome.
Common primidone side-effects | Cosa posso fare se sperimento questo? |
Feeling unsteady or tired | Getting up or moving more slowly should help. If this continues, let your doctor know |
Feeling sleepy, eyesight problems | Make sure your reactions are normal before you use tools or machines |
Feeling sick (nausea) | Attieniti a cibi semplici - evita pasti ricchi o piccanti |
Feeling short of breath, behavioural changes, mood changes (such as feeling irritable, confused, excited or depressed) | Se uno di questi diventa problematico, parla con il tuo medico |
Importante: your doctor will have discussed with you the possibility of some less common but more serious side-effects. Let your doctor know straightaway if you experience any of the following:
A high temperature (fever) and swollen glands.
A severe skin rash.
Yellowing of your skin or the whites of your eyes (jaundice).
Se si verificano altri sintomi che ritieni possano essere dovuti a questo medicinale, parla con il tuo medico o farmacista.
How to store primidone
Torna ai contenutiTenere tutti i medicinali fuori dalla portata e dalla vista dei bambini.
Conservare in un luogo fresco e asciutto, lontano da fonti di calore e luce diretta.
Informazioni importanti su tutti i medicinali
Torna ai contenutiInformazioni importanti su tutti i medicinali
Non assumere mai più della dose prescritta. Se sospetti che tu o qualcun altro possa aver assunto un sovradosaggio di questo medicinale, recati immediatamente al pronto soccorso del tuo ospedale locale. Porta con te il contenitore, anche se è vuoto.
Questo medicinale è per te. Non darlo mai ad altre persone, anche se la loro condizione sembra essere la stessa della tua.
Non conservare medicinali scaduti o indesiderati. Portali alla tua farmacia locale che li smaltirà per te.
Se hai domande su questo medicinale, chiedi al tuo farmacista.
Segnala effetti collaterali di un medicinale o vaccino
Se si verificano effetti collaterali, è possibile segnalarli online tramite il sito web Yellow Card.
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Ulteriori letture e riferimenti
- Manufacturer's PIL, Primidone 250 mg Tablets; SERB Laboratories, The electronic Medicines Compendium. Dated February 2024.
- Medicinali Completi BNF 89ª Edizione; Associazione Medica Britannica e Società Farmaceutica Reale di Gran Bretagna, Londra.
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Storia dell'articolo
Le informazioni su questa pagina sono scritte e revisionate da clinici qualificati.
Next review due: 5 Apr 2028
5 Apr 2025 | Ultima versione

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