Lamivudine for hepatitis B infection

About lamivudine for hepatitis B infection

Hepatitis means inflammation of the liver. Some viruses can cause hepatitis (although there are several other causes too). Epatite B is a virus which is carried in your bloodstream to your liver. It can affect and damage your liver. Following an infection with hepatitis B, a few people develop a persistent infection called chronic hepatitis B.

People with chronic hepatitis B usually need treatment to stop or to reduce the activity of the virus. This limits damage to the liver, which is a complication of the infection. One of the types of treatment currently given is an antiviral medicine. Antiviral medicines like lamivudine work by stopping the hepatitis B virus from multiplying (replicating); this reduces the amount of the virus in your body. A doctor who is a liver specialist will usually start the treatment for you. Treatment for chronic hepatitis B usually continues for several years and can include more than one antiviral medicine.

Lamivudine is also prescribed for another viral infection - there is more information about this in a separate medicine leaflet called Lamivudine for HIV.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking lamivudine it is important that your doctor knows:

• Se sei incinta o stai allattando.

• If you have problems with the way your kidneys work.

• Se stai assumendo altri medicinali. Questo include qualsiasi medicinale disponibile per l'acquisto senza prescrizione, così come i medicinali a base di erbe e complementari.

• Se hai mai avuto una reazione allergica a un medicinale.

• Before you start the treatment, read the manufacturer's printed information leaflet from inside your pack. It will give you more information about lamivudine, and it will also provide you with a full list of the side-effects which you could experience from taking it.

• The usual dose is one 100 mg tablet daily. Take lamivudine exactly as your doctor tells you to - your dose will be printed on the label of the pack to remind you about what the doctor said to you.

• It is recommended that you swallow the tablet whole (not chewed or crushed). Take it with a drink of water.

• Try to take lamivudine at the same time each day, as this will help you to remember to take it regularly. You can take the tablet either with or without food.

• If you forget to take a dose, take it as soon as you remember. If you do not remember until the following day, leave out the missed dose. Do not take two doses together to make up for a forgotten dose.
  

• Mantieni i tuoi appuntamenti regolari con il tuo medico. Questo è necessario affinché i tuoi progressi possano essere monitorati. Avrai bisogno di fare alcuni esami del sangue di tanto in tanto.

• It is important that you continue to take lamivudine regularly. Treatment for hepatitis B can be long-term. Continue to take the tablets, even if you feel well. This is to keep your liver healthy.

• Treatment with lamivudine does not stop you from passing the infection on to others through sexual contact, sharing needles to inject drugs, or from mother to baby. A vaccine is available which protects against hepatitis B and can be offered to your sexual and household contacts who are at risk of being infected. Do not have sex with anyone (especially any sex without using a condom) until they have been fully immunised and have had their blood checked to see that the immunisation has worked.

• Alla maggior parte delle persone con epatite B cronica verrà consigliato di seguire una dieta normale, sana ed equilibrata. Tuttavia, è probabile che ti venga consigliato di non bere alcolici. L'alcol aumenterà il rischio e la velocità con cui si sviluppano danni al fegato.

• Each time you collect a new supply of these tablets from your pharmacy, make sure they look to be the same as you have had before. This is because there is another brand of lamivudine available which is used to treat a different type of infection. If you are unsure about your prescription in any way, ask your pharmacist to check it out for you.

• Lamivudine has been associated with a serious side-effect in some people who have taken it for another type of infection. This is known as lactic acidosis. It is a problem where there is too much lactic acid in the blood. The symptoms associated with it are listed in the next section 'Can lamivudine cause problems?'. Although this has occurred in only a very few people who have taken it for hepatitis B, you must let your doctor know immediatamente if you develop any of the symptoms listed below.

• If you buy any medicines, supplements or herbal remedies 'over the counter', check with a pharmacist that they are suitable to take with lamivudine and your other medicines.

• Se devi sottoporti a un'operazione o a un trattamento dentistico, informa la persona che esegue il trattamento sui medicinali che stai assumendo.

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with lamivudine. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

• Sensazione di malessere (nausea) o vomito, dolore addominale, perdita di appetito, perdita di peso, sensazione di debolezza o vertigini, e respirazione rapida o affannosa.

Se si verificano altri sintomi che ritieni possano essere dovuti alle compresse, parla con il tuo medico o farmacista per ulteriori consigli.

• Tenere tutti i medicinali fuori dalla portata e dalla vista dei bambini.

• Conservare in un luogo fresco e asciutto, lontano da fonti di calore e luce diretta.