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Unguento rettale di trinitrato di glicerile

Rectogesic

Glyceryl trinitrate rectal ointment can ease the pain associated with small tears of skin around the back passage (anal fissures).

Use the ointment twice daily at 12-hourly intervals. You can use it for up to eight weeks if necessary.

The most common side-effect is a headache.

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About glyceryl trinitrate rectal ointment

Tipo di medicinale

Un nitrato

Utilizzato per

Pain relief for anal fissures (in adults)

Chiamato anche

Nitroglycerin (in US); Rectogesic®

Disponibile come

Rectal ointment

Un fessura anale is a small tear of the skin around your back passage (anus). Glyceryl trinitrate (GTN) rectal ointment (Rectogesic®) works by relaxing the muscle just inside your back passage. Relaxing this muscle increases the flow of blood to the area, which eases pain. It can be helpful where other treatments have not been effective.

A different brand of glyceryl trinitrate ointment (Percutol®) is used to relieve angina pain. For information on this product please see our medicine leaflet Trinitrato di glicerile per l'angina.

To make sure that this is the right treatment for you, before you start using GTN rectal ointment it is important that your doctor knows:

  • Se sei incinta o stai allattando.

  • Se hai problemi con il funzionamento del tuo fegato, o problemi con il funzionamento dei tuoi reni.

  • If you have migraines or severe headaches.

  • If you have low blood pressure, or a heart condition.

  • Se ti è stato detto da un medico che hai bassi livelli di ferro nel sangue (anemia), o bassi livelli di ossigeno nel sangue (ipossiemia).

  • Se hai una ghiandola tiroidea ipoattiva.

  • Se hai una condizione oculare chiamata glaucoma.

  • Se hai avuto di recente un trauma cranico o un attacco di cuore.

  • Se hai mai avuto una reazione allergica a un medicinale.

  • If you are taking other medicines, including those available to buy without a prescription, as well as herbal or complementary medicines. It is particularly important that you tell your doctor if you are using any medicines to help treat erectile dysfunction.

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  • Before you use the ointment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about using the ointment, and it will also provide you with a full list of side-effects which you could experience.

  • Cover your finger with a finger cot (available from pharmacies), or a piece of cling film, or use a disposable glove. Then measure out 2.5 cm of the ointment from the tube on to your finger (there is a measuring line on the packaging to help you). Then, using your finger, gently insert the ointment just inside your back passage. To make sure that the ointment gets to the correct place, insert your finger to the first finger joint. Apply the ointment this way every 12 hours until the pain goes away. You can continue to use the ointment for up to eight weeks, if needed.

  • Remember to follow any lifestyle or dietary advice you have been given by your doctor. Try to avoid becoming constipated, by eating a high-fibre diet and drinking several glasses of water each day.

  • It is best not to drink alcohol while you are using GTN rectal ointment. Alcohol will increase the chance that you experience side-effects such as feeling dizzy and light-headed.

  • If you experience any bleeding from your back passage, or if your symptoms do not improve, you should discuss this with your doctor.

  • If you buy any medicines, check with a pharmacist that they are suitable for you to take while you are using GTN rectal ointment.

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Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with GTN rectal ointment. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Very common glyceryl trinitrate rectal ointment side-effects (these affect more than 1 in 10 people)

Cosa posso fare se sperimento questo?

Mal di testa

Ask your pharmacist to recommend a suitable painkiller. If the headache is severe or if it continues, please ask your doctor for further advice

Common glyceryl trinitrate rectal ointment side-effects (these affect fewer than 1 in 10 people)

Cosa posso fare se sperimento questo?

Feeling light-headed or dizzy

Non guidare e non utilizzare strumenti o macchinari mentre sei sotto effetto

Sensazione di nausea

Try to stick to simple meals (avoid rich or spicy foods). If it becomes troublesome, please speak with your doctor

Less common glyceryl trinitrate rectal ointment side-effects

Cosa posso fare se sperimento questo?

Blurred vision, diarrhoea, local burning or itching

If any become troublesome, please speak with your doctor

If you experience any other symptoms which you think may be due to the ointment, please speak with your doctor or pharmacist for further advice.

  • Once opened, do not store or use the ointment for longer than eight weeks.

  • Tenere tutti i medicinali fuori dalla portata e dalla vista dei bambini.

  • Conservare in un luogo fresco e asciutto, lontano da fonti di calore e luce diretta.

Informazioni importanti su tutti i medicinali

Never use more than the prescribed dose. If you suspect that someone might have swallowed some of the ointment by accident, go to the accident and emergency department of your local hospital. Take the container with you, even if it is empty.

Questo medicinale è per te. Non darlo mai ad altre persone, anche se la loro condizione sembra essere la stessa della tua.

If you are having an operation or dental treatment, please remember to tell the person carrying out the treatment which medicines you are taking/using.

Non conservare medicinali scaduti o indesiderati. Portali alla tua farmacia locale che li smaltirà per te.

Se hai domande su questo medicinale, chiedi al tuo farmacista.

Segnala effetti collaterali di un medicinale o vaccino

Se si verificano effetti collaterali, è possibile segnalarli online tramite il Yellow Card website.

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Ulteriori letture e riferimenti

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About the authorView full bio

Author image

Michael Stewart, MRPharmS

Medicine Leaflet Review Manager – Contractor, Pharmacist

BPharm (Hons), MRPharmS

Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.

About the reviewer

Author image

Sid Dajani

Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.

Storia dell'articolo

Le informazioni su questa pagina sono scritte e revisionate da clinici qualificati.

  • Prossima revisione prevista: 16 ott 2027
  • 20 Ott 2024 | Ultima versione

    Ultimo aggiornamento di

    Michael Stewart, MRPharmS

    Revisione paritaria di

    Sid Dajani
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