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Duloxetina per i sintomi urinari

Yentreve

The brand of duloxetine called Yentreve® is prescribed for women with stress incontinence. Take one capsule twice daily, in the morning and late afternoon. You may be given generic duloxetine capsules; 20 mg and 40 mg capsules are prescribed for stress incontinence.

Remember to do the exercises you have been given to strengthen your pelvic floor muscles.

Each time you collect a new supply of capsules, make sure the strength (20 mg or 40 mg) is the same as you have taken previously. If not, please speak with your pharmacist who will advise you.

A colpo d'occhio

  • Duloxetine is a medicine used to treat symptoms of stress incontinence in women.

  • It is prescribed when pelvic floor exercises alone are not enough, or if surgery is not suitable.

  • It works by strengthening muscles around the bladder outlet to control urine flow.

  • You typically take one capsule twice daily, usually 40mg, but may start on a lower dose.

  • Common side effects include feeling sick, dry mouth, and constipation.

  • If you experience side effects or distressing thoughts, speak to your doctor immediately.

About duloxetine for urinary symptoms

Tipo di medicinale

A serotonin and noradrenaline reuptake inhibitor

Utilizzato per

Symptoms of stress incontinence in women

Chiamato anche

Yentreve®

Disponibile come

Capsule

Incontinenza da stress is the most common form of incontinence. It means you pass urine with things like coughing, sneezing or exercise. It happens when the pelvic floor muscles that support your bladder are weakened. Childbirth is a common reason for a weak pelvic floor. The main treatment for stress incontinence is pelvic floor exercises. Surgery to tighten or support your bladder outlet can also help.

Duloxetine may be advised if esercizi del pavimento pelvico alone are not helping to treat your stress incontinence. It is usually advised in women who do not want to undergo surgery, or in women who have health problems that may mean that surgery is unsuitable.

Duloxetine is thought to work by interfering with certain chemicals (called serotonin and noradrenaline) that are used within the nerves that send messages to your pelvic floor muscles. This helps the muscles around the bladder outlet to contract more strongly, and this in turn controls the flow of urine and helps to prevent any leakage.

Duloxetine is also prescribed for the treatment of some mood and nerve disorders, although a different brand and strength of capsule are used. There is a separate medicine leaflet called Duloxetina per disturbi dell'umore e nervosi which gives more information about duloxetine when it is used for this type of condition.

Before taking duloxetine

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking duloxetine it is important that your doctor knows:

  • Se sei incinta, stai cercando di avere un bambino o stai allattando.

  • Se hai problemi con il funzionamento del tuo fegato, o problemi con il funzionamento dei tuoi reni.

  • Se hai una condizione cardiaca.

  • Se hai una pressione oculare elevata (chiamata glaucoma).

  • Se hai la pressione alta.

  • If you have ever had 'high' moods, such as mania in bipolar disorder.

  • Se hai mai avuto una crisi (convulsione).

  • If you have a blood disorder that increases your risk of bleeding.

  • Se stai assumendo o utilizzando altri medicinali. Questo include qualsiasi medicinale che stai assumendo e che è disponibile per l'acquisto senza prescrizione, così come i medicinali a base di erbe e complementari.

  • Se hai mai avuto una reazione allergica a un medicinale.

How to take duloxetine

  • Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about duloxetine and will provide you with a full list of the side-effects which you may experience from taking it.

  • Take duloxetine exactly as your doctor tells you to. The usual dose is one 40 mg capsule twice daily (in the morning and late afternoon). If you are taking duloxetine for the first time, your doctor may give you the lower 20 mg strength capsule for a couple of weeks - this is to help avoid any unwanted symptoms when you first take duloxetine.

  • Try to take your doses at the same times of day each day, as this will help you to remember to take your doses regularly. You can take duloxetine either before or after meals. Take the capsules with a drink of water to help you to swallow.

  • Se dimentichi di prendere una dose al solito orario, prendila quando te ne ricordi. Tuttavia, se è quasi ora di prendere la dose successiva quando te ne ricordi, salta la dose dimenticata e prendi la dose successiva quando è il momento. Non prendere due dosi insieme per compensare una dose dimenticata.

Ottenere il massimo dal tuo trattamento

  • Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress and review your treatment.

  • Remember to do the exercises you have been given to strengthen your pelvic floor muscles. This is important because the majority of people with stress incontinence are much improved with these exercises.

  • If you have been advised to reduce your weight, try to stick to the advice you have been given about your diet. Losing even a modest amount of weight can help to improve your symptoms.

  • Smoking can cause coughing which can aggravate your symptoms. It would help to not smoke. If you are a smoker and you need help to quit, ask your doctor or pharmacist for advice.

  • Drinking alcohol can increase the risk of unwanted effects from duloxetine, such as dizziness and blurred vision.

  • If you buy any medicines, check with a pharmacist that they are suitable to take with duloxetine. This is because some herbal medicines (such as St John's wort) can increase the chance that you will experience unwanted effects.

  • If you are having an operation or dental treatment, tell the person carrying out the treatment that you are taking duloxetine.

  • Keep taking duloxetine until your doctor tells you otherwise. Stopping suddenly can cause problems and your doctor may want you to reduce your dose gradually when this becomes necessary.

Can duloxetine cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the common ones associated with duloxetine. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Very common duloxetine side-effects (these affect more than 1 in 10 people)

Cosa posso fare se sperimento questo?

Sensazione di nausea

Mangia pasti semplici - evita cibi ricchi o piccanti

Bocca secca

Prova a masticare gomme senza zucchero o a succhiare caramelle senza zucchero

Costipazione

Cerca di seguire una dieta equilibrata e bevi diversi bicchieri d'acqua ogni giorno

Common duloxetine side-effects (these affect fewer than 1 in 10 people)

Cosa posso fare se sperimento questo?

Blurred vision, feeling tired, dizzy or sleepy

Do not drive and do not use tools or machines while affected. Avoid alcohol

Diarrea

Bevi molta acqua per reintegrare i liquidi persi

Mal di testa

Ensure you are drinking the recommended amount of fluids each day. Ask your pharmacist to recommend a suitable painkiller. If the headaches continue, let your doctor know

Lack of appetite, indigestion, stomach pain, flushing, increased blood pressure, difficulty sleeping, feeling anxious, skin tinglings, feeling shaky, reduced interest in sex, increased sweating

Discuti questi con il tuo medico se qualcuno diventa problematico

Importante: if you develop any depressing or distressing thoughts or ideas, you should let your doctor know about this as soon as possible. When this medicine is prescribed for people with depression or anxiety, it can increase the risk of suicidal thoughts, particularly when the treatment is first started.

On rare occasions, medicines that affect the level of serotonin in the brain can cause it to go too high and cause problems. The risk is higher if you are taking another medicine with this effect (such as an antidepressant). Seek medical attention if you develop any combination of the following:

  • Muscoli rigidi o movimenti 'scattosi'.

  • Battito cardiaco insolitamente veloce.

  • Alta temperatura (febbre).

  • Sensazione di malessere (nausea) o vomito, diarrea.

  • Sensazione di delirio o visione di allucinazioni.

If you experience any other symptoms which you think may be due to the capsules, please speak with your doctor or pharmacist for further advice.

How to store duloxetine

  • Tenere tutti i medicinali fuori dalla portata e dalla vista dei bambini.

  • Conservare in un luogo fresco e asciutto, lontano da fonti di calore e luce diretta.

Informazioni importanti su tutti i medicinali

Informazioni importanti su tutti i medicinali

Non assumere mai più della dose prescritta. Se sospetti che tu o qualcun altro possa aver assunto un sovradosaggio di questo medicinale, recati al pronto soccorso del tuo ospedale locale. Porta con te il contenitore, anche se è vuoto.

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Domande frequenti

Can I take duloxetine if I am already taking other medications?

It is important to inform your doctor about all other medicines you are currently taking, including those bought without a prescription, and herbal or complementary medicines. Some medicines may not be suitable to take with duloxetine, or may require extra care.

What should I do if I forget to take a dose of duloxetine?

If you forget a dose at your usual time, take it as soon as you remember. However, if it's almost time for your next dose, skip the missed dose and just take your next dose when it is due. Never take two doses together to make up for a forgotten dose.

How long will I need to take duloxetine for my stress incontinence?

You should continue taking duloxetine until your doctor advises you to stop. When stopping, your doctor may suggest reducing your dose gradually instead of stopping suddenly to avoid potential problems.

Are there any specific lifestyle changes that can help improve my stress incontinence while taking duloxetine?

Yes, several lifestyle changes can help. It's important to continue performing any pelvic floor exercises you've been given. If you've been advised to lose weight, doing so, even a modest amount, can help. Quitting smoking can also reduce coughing, which might aggravate symptoms. Additionally, limiting alcohol intake can help prevent unwanted side-effects like dizziness and blurred vision while on duloxetine.

What happens if I need an operation or dental work while taking duloxetine?

If you are scheduled for an operation or dental treatment, you should inform the healthcare professional carrying out the treatment that you are taking duloxetine.

Ulteriori letture e riferimenti

Informazioni sull'autoreVisualizza il profilo completo

Immagine dell'autore

Michael Stewart, MRPharmS

Responsabile Revisione Foglietti Illustrativi – Contrattista, Farmacista

BPharm (Hons), MRPharmS

Michael è un farmacista comunitario che esercita nelle Midlands e nel South Yorkshire con oltre 20 anni di esperienza nel consigliare su farmaci e condizioni mediche. Ha una solida esperienza nella formazione sanitaria, avendo prodotto e tenuto corsi di formazione per team di farmacia e personale di strutture di assistenza residenziale, inclusi infermieri. Ha anche contribuito a consigli consultivi farmaceutici per la gestione di condizioni a bassa gravità nella comunità.

Informazioni sul recensore

Immagine dell'autore

Sid Dajani

Sultan Dajani si è laureato alla London School of Pharmacy nel 1994 ed è diventato il più giovane membro eletto del consiglio della Royal Pharmaceutical Society dalla sua fondazione nel 1842.

Storia dell'articolo

Le informazioni su questa pagina sono scritte e revisionate da clinici qualificati.

  • Next review due: 24 Aug 2027
  • 23 Ago 2024 | Ultima versione

    Ultimo aggiornamento di

    Michael Stewart, MRPharmS

    Revisione paritaria di

    Sid Dajani
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