Sindrome di Diogene
Revisione paritaria di Dr Krishna Vakharia, MRCGPAutore Dr Colin Tidy, MRCGPPubblicato originariamente 27 Lug 2023
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Non è raro avere una sensazione di depersonalizzazione (non sentirsi come se stessi) per brevi periodi, come quando ci si sente molto stressati, ma a volte il problema può durare a lungo e causare molte difficoltà e angoscia.
A colpo d'occhio
Depersonalisation is feeling unreal, detached from your body or thoughts, or like an outside observer.
Derealisation is experiencing other people or the world as strange or unreal.
Temporary feelings can happen due to stress, exhaustion, illness, or drugs.
Persistent depersonalisation may be diagnosed as depersonalisation-derealisation disorder.
Symptoms often begin in teenage years and can be made worse by stress, anxiety, or lack of sleep.
Professional help should be sought if symptoms cause significant distress or affect daily life.
Treatment involves lifestyle changes, psychotherapy, and sometimes medication such as SSRIs.
Supporto per la salute mentale di adulti e bambini
Terapia cognitivo-comportamentale (CBT) e psicoterapia online per adulti e bambini dagli 8 ai 17 anni. I professionisti accreditati di Onebright supportano le persone che affrontano ansia, depressione e altre difficoltà emotive.
What is depersonalisation?
Depersonalisation means that you don’t feel like yourself anymore, feeling yourself as strange or unreal, or feeling empty and detached from reality. It might seem as though your mind and body are operating separately from one another.
Depersonalisation may take the form of emotional and/or physical numbing, a sense of watching yourself from a distance or ‘being in a play’, or changes in how you sense things, such as a distorted sense of time.
The difference between depersonalisation and derealisation
Derealisation is slightly different to depersonalisation. Derealisation means experiencing other people, objects, or the world as strange or unreal (eg, dreamlike, distant, foggy, lifeless, colourless, or visually distorted).
Depersonalisation and derealisation can be very unsettling and explaining the experience to others can be very difficult, with a fear of being thought of as ‘mad’ when trying to describe the sense of disconnection and hazy thinking. It can be easy to be convinced that you're losing touch with reality completely.
Temporary feelings of depersonalisation or derealisation can occur when you are under stress, during extreme emotional states or exhaustion, when physically ill, or under the influence of recreational drugs. it's only when these experiences are persistent or keep happening that the diagnosis of depersonalisation-derealisation disorder is used. Episodes of symptoms in depersonalisation-derealisation disorder may be associated with adverse life events or conflicts with others.
Symptoms of depersonalisation
The onset of Depersonalisation-Derealisation Disorder can occur in childhood but more often it starts in the mid-teenage years, with an average age at onset of about 16 years of age. Developing symptoms for the first time after 25 years of age is very rare.
The onset of depersonalisation-derealisation disorder can vary from sudden to gradual, with initial episodes of limited severity and frequency, gradually replaced by symptoms that are more severe and persistent.
Episodes of depersonalisation-derealisation disorder can vary in duration, ranging from brief (hours or days) to prolonged (weeks, months or years). Factors such as emotional stress, anxiety, lack of sleep or recreational drug use can make symptoms much worse. The problem is usually long lasting (chronic) and persistent.
The symptoms of depersonalisation may include:
Feeling unreal and that you're an outside observer of your thoughts, feelings and your body, as if you were floating in air above yourself.
Feeling like a robot or that you're not in control of your speech or movements.
The sense that your body, legs or arms appear distorted, enlarged or shrunken, or that your head is wrapped in cotton wool.
Unable to feel emotion and a numbness of your senses or responses to the world around you.
A sense that your memories lack emotion, and that they may or may not be your own memories.
A common associated symptom in depersonalisation-derealisation disorder is an altered sense of time, such as a feeling of time slowing down or speeding up. There may also be frequent fears of ‘going crazy’, as well as a loss of the sense of ‘ownership’ of some of your personal memories, or reduced emotional responses.
Depersonalisation-derealisation disorder often occurs with other mental health disorders including depressione, anxiety disorder, attacchi di panico, disturbo ossessivo compulsivo (DOC), or phobias, or with a personality disorder.
Causes of depersonalisation
While there is no known single, identifiable cause for depersonalisation, there are some common risk factors associated with it:
Trauma.
Stress grave.
Depressione.
Ansia.
Panic disorder.
Emotional maltreatment in childhood.
Marijuana (cannabis) use.
Hallucinogenic or psychedelic use.
Recreational drug use, especially of marijuana or hallucinogens, is a common trigger for depersonalisation and derealisation symptoms. However, depersonalisation-derealisation disorder can only be diagnosed if the symptoms persist beyond the period of intoxication or withdrawal from these substances.
Therefore, depersonalisation can be caused by a range of different factors and each person will have different circumstances leading to their symptoms.
Diagnosing depersonalisation
The diagnosis of depersonalisation-derealisation disorder can also only apply if the symptoms cannot be explained by any other mental health or other problem, or any effect of recreational drugs or medications.
For the diagnosis to be made, the symptoms of depersonalisation-derealisation disorder should result in significant distress or problems with personal, family or social life, and with education or work. If it is possible to function normally, it is only through a great deal of additional effort.
A mental healthcare professional (such as a psychologist or psychiatrist) will make an assessment of your symptoms to see whether they are consistent with the diagnosis. The assessment will include a very thorough history of your symptoms and an assessment of the possible underlying causes of your symptoms.
The assessment for the diagnosis of depersonalisation will also be used to gain understanding of the circumstances leading up to your symptoms, in order to identify potential triggers. In this way, specific ways to target the underlying problems that are driving your symptoms can be considered.
Treatment for depersonalisation
The way you experience depersonalisation and derealisation is specific and unique to you, which is why a personalised approach is most effective in treating depersonalisation. The different treatments can be used in combination.
Cambiamenti nello stile di vita
Getting enough sunlight exposure.
Psicoterapia
Psychotherapy can be very effective for treating depersonalisation, even if you have severe symptoms. Like all treatments, psychotherapy needs to be adapted to the specific needs of each individual person.
Sometimes the type of psychotherapy needs to be changed between being supportive when symptoms are particularly difficult to deal with, and then more dynamic when symptoms are much less severe.
Therefore, during times of severe difficulty with depersonalisation symptoms or severe depression and anxiety, supportive interventions (crisis interventions and reinforcing coping skills and strategies) are usually the most appropriate.
During periods of relatively mild symptoms a more dynamic (psychodynamic) approach, such as terapia cognitivo-comportamentale (TCC), may be used, focusing on self-reflection and self-evaluation, to explore effective coping strategies and relationship patterns.
Medicazione
There is no recognised medicine to help treat depersonalisation. However, there is some evidence to support the use of selective serotonin reuptake inhibitor (SSRI) antidepressants, and more recently the combination of a medicine called lamotrigina with an SSRI has shown some benefit.
Qual è il risultato?
The outcome for derealisation and depersonalisation is often good. A large number of people get better with time and others respond well to treatments, particularly to psychotherapy.
Scelte del paziente per Altri problemi di salute mentale

Salute mentale
Somatizzazione e disturbi funzionali
Somatisation is no longer a commonly used term. What used to be considered somatising symptoms or somatoform disorders are now more commonly termed "functional disorders" or "functional symptoms". Terminology can be confusing; lots of different terms are used and some terms have been changed in recent years. Illness is what we experience when we feel unwell. Sometimes this is caused by a disease process that can be tested for and found. Sometimes this is caused by other factors - social, psychological or biological - that don't arise out of a disease but that nonetheless can cause significant symptoms and significant illness.
di Dr Philippa Vincent, MRCGP

Salute mentale
Disturbi psicosomatici
Psicosomatico significa mente (psiche) e corpo (soma). Un disturbo psicosomatico è una malattia che coinvolge sia la mente che il corpo.
di Dr Caroline Wiggins, MRCGP
Domande frequenti
Can depersonalisation be misdiagnosed as another condition?
Yes, for a diagnosis of depersonalisation-derealisation disorder to be made, it's essential that the symptoms cannot be explained by any other mental health issue, other medical problems, recreational drugs, or medications. A thorough assessment will rule out these other possibilities.
How long do depersonalisation symptoms typically last?
Episodes of depersonalisation-derealisation disorder can vary in duration, ranging from brief periods of hours or days to more prolonged experiences lasting weeks, months, or even years. The condition is often described as chronic and persistent.
Will I always experience depersonalisation if I have other mental health conditions?
Depersonalisation-derealisation disorder often occurs alongside other mental health conditions such as depression, anxiety disorder, panic attacks, obsessive-compulsive disorder (OCD), phobias, or a personality disorder. However, not everyone with these conditions will develop depersonalisation.
How can I support someone experiencing depersonalisation?
The article focuses on individual experience and treatment. While it acknowledges the difficulty in explaining the experience to others, it doesn't provide specific guidance for third-party supporters. However, understanding the description of the condition (feeling unreal, detached, or watching oneself) and its associated fears (like 'going crazy') could help in providing empathetic support. Encouraging them to seek professional assessment and treatment would be beneficial.
Ulteriori letture e riferimenti
- Classificazione Internazionale delle Malattie 11ª Revisione; Organizzazione Mondiale della Sanità, 2019/2021
- Somer E, Amos-Williams T, Stein DJ; Evidence-based treatment for Depersonalisation-derealisation Disorder (DPRD). BMC Psychol. 2013 Oct 28;1(1):20. doi: 10.1186/2050-7283-1-20. eCollection 2013.
- Mishra S, Das N, Mohapatra D, et al; Mindfulness-Based Cognitive Therapy in Depersonalization-Derealization disorder: A Case Report. Indian J Psychol Med. 2022 Nov;44(6):620-621. doi: 10.1177/02537176211040259. Epub 2021 Sep 28.
- Gentile JP, Snyder M, Marie Gillig P; STRESS AND TRAUMA: Psychotherapy and Pharmacotherapy for Depersonalization/Derealization Disorder. Innov Clin Neurosci. 2014 Jul;11(7-8):37-41.
Informazioni sul recensoreVisualizza il profilo completo

Dr Krishna Vakharia, MRCGP
Direttore Sanitario per la Salute, Optum UK
MBChB, MRCGP(2013), BMedSci (hons), DFSRH, DRCOG, PGDipDerm (Distn)
La Dott.ssa Krishna Vakharia è un medico di base del NHS. È anche un'esaminatrice regolare per il Diploma post-laurea in Dermatologia Pratica presso l'Università di Cardiff, oltre ad essere il Direttore Medico per la salute presso Optum UK.
Storia dell'articolo
Articolo disponibile anche in Inglese, Tedesco, Spagnolo, Francese, Italiano, Portoghese, Hindi, Ebraico, Arabo, and Svedese.
Prossima revisione prevista: 25 Lug 2028
27 Lug 2023 | Pubblicato originariamente
Autore:
Dr Colin Tidy, MRCGPRevisione paritaria di
Dr Krishna Vakharia, MRCGP
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