Salta al contenuto principale

Soluzione orale di metadone

Metharose, Physeptone

Questo medicinale è un antidolorifico oppioide. Esiste un serio rischio di dipendenza quando si assume questo medicinale, specialmente se usato a lungo termine. The Medicines and Healthcare products Regulatory Agency (MHRA) has issued nuove linee guida per le persone a cui è stato prescritto un antidolorifico oppioide. Se hai domande o preoccupazioni sull'assunzione sicura di oppioidi, ti preghiamo di parlare con il tuo medico o un farmacista.

Methadone oral solution is a substitute for street drugs like heroin which cause dependence and addiction.

It is important for you to continue to take methadone regularly, every day.

You are more likely to succeed in staying off heroin if you have support. Please ask about what counselling and help are available in your area.

A colpo d'occhio

  • Methadone is a medicine used to help manage opioid dependence and addiction.

  • It is usually taken once a day as a liquid or tablet to prevent withdrawal symptoms.

  • You must take methadone exactly as prescribed by your doctor.

  • Do not drink alcohol or take street drugs while on methadone, as this increases overdose risk.

  • Do not stop taking methadone without first talking to your doctor.

  • Get medical help immediately if you suspect an overdose or if a child swallows methadone.

About methadone

Tipo di medicinale

An opioid substitution therapy

Utilizzato per

To help manage opioid dependence and addiction in adults (such as heroin addiction)

Chiamato anche

Metharose®, Physeptone®

Disponibile come

Oral solution, tablets

Methadone is prescribed to help you keep off droghe da strada such as heroin. It can help to prevent the unpleasant withdrawal symptoms which can occur when you stop using drugs like these. It is taken by mouth as an oral liquid and it works as a substitution treatment. Many people choose to stay on methadone long-term, although some people gradually reduce their dose and come off it.

The effects of methadone last longer than heroin so it is usually prescribed as a once-daily dose. To begin with, you will usually be asked to take it under the supervision of the person who dispenses the methadone to you. This means there can be no doubt about how much methadone you take at each dose. This supervision may be relaxed after a few months of you taking a regular maintenance dose.

Methadone also acts as a painkiller. It is occasionally used to treat severe pain if other strong painkillers are unsuitable. If you have been prescribed methadone for this reason then you should speak with your doctor or home-care team if you have any questions about your treatment. This document gives information about methadone when it is used to manage drug addiction only.

Before taking methadone

To make sure that this is the right treatment for you, before you start taking methadone it is important that your doctor or pharmacist knows:

  • Se sei incinta o stai allattando.

  • Se hai problemi alla prostata o difficoltà a urinare.

  • Se hai problemi respiratori, come l'asma o la broncopneumopatia cronica ostruttiva (BPCO).

  • If you have been told you have low blood pressure or an unusual heart rhythm.

  • Se hai problemi con la tiroide o le ghiandole surrenali.

  • If you have fits or epilepsy.

  • If you have a problem with the way your liver works or a problem with the way your kidneys work.

  • Se hai un problema con il tuo dotto biliare.

  • Se sei stato stitico per più di una settimana o hai un problema infiammatorio intestinale.

  • Se hai una condizione che causa debolezza muscolare, chiamata miastenia grave.

  • Se hai avuto di recente una grave lesione alla testa.

  • Se hai mai avuto una reazione allergica a un medicinale.

  • Se stai assumendo altri medicinali. Questo include qualsiasi medicinale che stai assumendo e che è disponibile per l'acquisto senza prescrizione medica, così come i medicinali a base di erbe e complementari.

How to take methadone

  • Carefully follow the advice your doctor has given to you and read any printed information you have been given. The manufacturer's printed information leaflet (which will be supplied with the medicine) will give you more information about methadone and will provide you with a full list of the side-effects which you could experience from taking it.

  • Take methadone exactly as your doctor tells you to. Do not take more, or less, than the dose you have been prescribed. It is usually prescribed as a once-daily dose

  • Try to take your dose at the same time of day, each day. Initially you will be asked to take methadone where you can be supervised. This is to help you stick with your treatment and make sure you do not miss any doses.

  • At first your doctor will prescribe a low-ish dose and then see you frequently to adjust this to a regular maintenance dose. This early stage is very important because too high a dose can cause you serious harm, so please be patient. It may take a few weeks until the correct dose is found and you may have some minor withdrawal symptoms during this time. The correct dose varies from person to person, depending on how much heroin you were using and how your body deals with (metabolises) methadone.

  • If you miss a dose, wait until it is time for your next dose and take this next dose when it is due. Do fare affidamento take two doses together to make up for a missed dose. It is important that you tell your doctor you have missed a dose. If you miss more than three days of methadone, your dose will need to be changed.

Ottenere il massimo dal tuo trattamento

  • It is important that you keep your regular appointments with your doctor/clinic so that your progress can be reviewed. You will be asked to give a urine sample from time to time.

  • You are more likely to succeed in staying off heroin if you have support and counselling. Local drug community teams, self-help groups and other agencies can be of help. It is much harder to 'do it alone', so go for counselling and help if it is available in your area.

  • Methadone causes drowsiness and will affect your ability to drive. It is against the law to drive if your driving ability is impaired by this medicine. Even if your driving is not impaired, you will be guilty of an offence unless the methadone has been prescribed for a medical reason e it has been taken according to the instructions given by the prescriber.

  • Do not take more than the dose your doctor has prescribed for you. Signs of overdose can include pinpoint pupils, shallow breathing and, eventually, unconsciousness. If you suspect that you or someone else might have had an overdose of methadone, contact a doctor or go to the accident and emergency department of a local hospital straightaway. Take the container with you, even if it is empty.

  • You should not take any street drugs or drink alcohol while you are on methadone. This is because other street drugs and/or alcohol can increase the risk of overdose and side-effects.

  • Methadone (even in small amounts) is a special hazard to children and other people if it is swallowed by accident. If you suspect that someone else has swallowed some methadone, please get medical help straightaway.

  • Do not stop taking methadone without discussing this with your doctor or drug-team worker first. It is important that methadone should be taken regularly to reduce the risk of withdrawal symptoms from occurring. Withdrawal symptoms from methadone are similar to those from heroin (they are less severe but last longer). When you are ready to consider becoming drug-free, your doctor or drug-team worker will be able to help you decide on the best way to do this in order to keep withdrawal effects to a minimum.

  • If you buy any medicines, please check with a pharmacist that they are safe to take with methadone.

  • If you are having an operation or dental treatment, please tell the person carrying out the treatment that you are taking methadone. It could interfere with an anaesthetic, if needed.

Can methadone cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with methadone. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Common methadone side-effects

Cosa posso fare se sperimento questo?

Sensazione di malessere (nausea) o vomito, dolore addominale

Attieniti a pasti semplici - evita cibi ricchi o piccanti

Costipazione

Segui una dieta equilibrata e bevi molta acqua ogni giorno

Feeling dizzy, faint or sleepy

Non guidare e non utilizzare strumenti o macchinari. Non bere alcolici

Bocca secca

Prova a masticare gomme senza zucchero o a succhiare caramelle senza zucchero

Other effects include: difficulty passing urine, mood changes, flushing, hypothermia, slow heartbeat, dry eyes and feeling restless

If any of these become particularly troublesome, speak with your doctor

Importante: le persone che assumono analgesici oppioidi, e i loro familiari e amici, dovrebbero essere consapevoli del rischio di overdose accidentale e sapere quando chiedere aiuto medico. Il rischio è maggiore se si assumono anche altri farmaci che causano sonnolenza. I segnali di aver assunto troppo farmaco includono:

  • Sensazione di molta sonnolenza o vertigini.

  • Sensazione di malessere (nausea) o vomito.

  • Difficoltà respiratorie.

  • Perdita di coscienza.

Se hai assunto più farmaci del previsto o qualcun altro ha accidentalmente ingerito il tuo medicinale, chiama un'ambulanza e comunica loro il nome del tuo farmaco.

If you experience any other symptoms which you think may be due to methadone, please speak with your doctor, clinic or pharmacist for further advice.

How to store methadone

  • Tenere tutti i medicinali fuori dalla portata e dalla vista dei bambini.

  • Conservare in un luogo fresco e asciutto, lontano da fonti di calore e luce diretta.

Informazioni importanti su tutti i medicinali

Informazioni importanti su tutti i medicinali

Non assumere mai più della dose prescritta. Se sospetti che tu o qualcun altro possa aver assunto un sovradosaggio di questo medicinale, recati al pronto soccorso del tuo ospedale locale. Porta con te il contenitore, anche se è vuoto.

Questo medicinale è per te. Non darlo mai ad altre persone, anche se la loro condizione sembra essere la stessa della tua.

Non conservare medicinali scaduti o indesiderati. Portali alla tua farmacia locale che li smaltirà per te.

Se hai domande su questo medicinale, chiedi al tuo farmacista.

Segnala effetti collaterali di un medicinale o vaccino

Se si verificano effetti collaterali, è possibile segnalarli online tramite il Sito web Yellow Card.

verificatore di sintomi

Non sei sicuro di mescolare i medicinali?

Controlla le possibili interazioni tra farmaci, integratori e alimenti prima di assumerli insieme.

Domande frequenti

What is the difference between Metharose® and Physeptone®?

Metharose® and Physeptone® are both alternative brand names for methadone. They are the same medicine, just produced by different manufacturers. The article states that methadone is also called Metharose® and Physeptone®.

What should I do if I forget to tell my doctor about a health condition before starting methadone?

If you realise you forgot to mention a health condition, you should tell your doctor or pharmacist as soon as possible. The article states that it's important for your doctor or pharmacist to know about various conditions before you start taking methadone to ensure it's the right treatment for you.

Is it safe to get dental treatment while on methadone?

Yes, but you must inform your dentist or anyone else carrying out the treatment that you are taking methadone. This is important because methadone could interfere with an anaesthetic, if one is needed.

Ulteriori letture e riferimenti

Informazioni sull'autoreVisualizza il profilo completo

Immagine dell'autore

Michael Stewart, MRPharmS

Responsabile Revisione Foglietti Illustrativi – Contrattista, Farmacista

BPharm (Hons), MRPharmS

Michael è un farmacista comunitario che esercita nelle Midlands e nel South Yorkshire con oltre 20 anni di esperienza nel consigliare su farmaci e condizioni mediche. Ha una solida esperienza nella formazione sanitaria, avendo prodotto e tenuto corsi di formazione per team di farmacia e personale di strutture di assistenza residenziale, inclusi infermieri. Ha anche contribuito a consigli consultivi farmaceutici per la gestione di condizioni a bassa gravità nella comunità.

Informazioni sul recensore

Immagine dell'autore

Sid Dajani

Sultan Dajani si è laureato alla London School of Pharmacy nel 1994 ed è diventato il più giovane membro eletto del consiglio della Royal Pharmaceutical Society dalla sua fondazione nel 1842.

Storia dell'articolo

Le informazioni su questa pagina sono scritte e revisionate da clinici qualificati.

  • Prossima revisione prevista: 12 Set 2027
  • 14 Set 2024 | Ultima versione

    Ultimo aggiornamento di

    Michael Stewart, MRPharmS

    Revisione paritaria di

    Sid Dajani
verifica idoneità al vaccino antinfluenzale

Chiedi, condividi, connettiti.

Esplora le discussioni, fai domande e condividi esperienze su centinaia di argomenti di salute.

Iscriviti alla newsletter di Patient

La tua dose settimanale di consigli sulla salute chiari e affidabili - scritti per aiutarti a sentirti informato, sicuro e in controllo.

Per favore, inserisci un indirizzo email valido

Abbonandoti accetti i nostri Informativa sulla Privacy. Puoi annullare l'iscrizione in qualsiasi momento. Non vendiamo mai i tuoi dati.