Isosorbide mononitrate

About isosorbide mononitrate

Isosorbide mononitrate helps to prevent angina chest pain from developing. Angina pain develops if part of your heart muscle does not get as much blood and oxygen as it needs. It is usually caused by narrowing of your coronary arteries due to a build-up of a fatty substance called atheroma. The narrowing makes it more difficult for blood to flow to your heart muscle.

Isosorbide mononitrate works in two ways. It relaxes blood vessels in your body (causing them to widen) and this reduces the strain on your heart, making it easier for your heart to pump blood around your body. It also relaxes and widens blood vessels in your heart (coronary arteries) which increases the flow of blood to your heart muscle.

Isosorbide mononitrate is also sometimes prescribed alongside other medicines for people with insufficienza cardiaca. This is a condition where the heart does not beat as efficiently as it should.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking isosorbide mononitrate it is important that your doctor knows:

• Se sei incinta o stai allattando.

• Se hai problemi con il funzionamento del tuo fegato, o problemi con il funzionamento dei tuoi reni.

• Se hai la pressione bassa.

• Se ti è stato detto da un medico che hai bassi livelli di ferro nel sangue (anemia), o bassi livelli di ossigeno nel sangue (ipossiemia).

• Se hai una ghiandola tiroidea ipoattiva.

• Se hai una condizione oculare chiamata glaucoma.

• Se hai avuto di recente un trauma cranico o un attacco di cuore.

• Se hai mai avuto una reazione allergica a un medicinale.

• Se stai assumendo altri medicinali, inclusi quelli disponibili senza prescrizione medica, così come medicinali a base di erbe o complementari. È particolarmente importante che informi il tuo medico se stai usando qualsiasi medicinale per aiutare a trattare erectile dysfunction.

• Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about nitrate medicines, and it will also provide you with a full list of side-effects which you could experience from taking isosorbide mononitrate.

• Some brands of isosorbide mononitrate tablets should be taken two or three times a day. Longer-acting tablets and capsules are taken once daily in the morning. Your doctor will tell you which is the right dose for you, and this will also be printed on the label of the pack to remind you about what the doctor said to you. You can take your doses either before or after meals.

• Swallow the tablet/capsule whole - do not chew or crush it before you swallow. This is because the tablets/capsules are specially made to release the medicine they contain in a controlled way.

• If you forget to take a dose, take it as soon as you remember. If you do not remember until your next dose is nearly due, then leave out the forgotten dose and take your next dose when it is due. Do not take two doses together to make up for a missed dose.

• Isosorbide mononitrate tablets and capsules are not suitable to take to treat the pain of an angina attack. Your doctor will prescribe you a short-acting nitrate for you to take if this happens. Glyceryl trinitrate (GTN) is commonly prescribed for this.

• Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress

• The longer you take isosorbide mononitrate, the more your body can become used to it (called tolerance), and then it can have less of an effect. To avoid this, if you are taking more than one dose a day, your doses may not be prescribed at equal intervals throughout the day. It is important that you follow the instructions your doctor gives to you about when to take your doses.

• It is best not to drink alcohol while you are on isosorbide mononitrate. Alcohol will increase the risk of you experiencing side-effects such as feeling dizzy and light-headed.

• If you are having an operation or dental treatment, please remember to tell the person carrying out the treatment which medicines you are taking.

• If you buy any medicines, please check with a pharmacist that they are suitable for you to take with isosorbide mononitrate.

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with isosorbide mononitrate. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Se si verificano altri sintomi che ritieni possano essere dovuti al medicinale, ti preghiamo di consultare il tuo medico o farmacista per ulteriori consigli.

• Tenere tutti i medicinali fuori dalla portata e dalla vista dei bambini.

• Conservare in un luogo fresco e asciutto, lontano da fonti di calore e luce diretta.