Dutasteride per l'ingrandimento della ghiandola prostatica

About dutasteride

The prostate gland commonly becomes larger in older men. L'ingrossamento della ghiandola prostatica è anche chiamato iperplasia prostatica benigna (IPB). The prostate is situated close to the bladder, so its enlargement can cause problems with passing urine. Common symptoms that are experienced are having to wait before your urine starts to flow, taking longer at the toilet, dribbling urine, and a feeling that your bladder is not quite empty.

Dutasteride works by blocking the conversion of the hormone testosterone to the more potent hormone dihydrotestosterone. It does this by blocking an enzyme called 5-alpha reductase. Dihydrotestosterone is partly responsible for making the prostate enlarge. Therefore, a reduced amount of dihydrotestosterone in the prostate causes it to shrink. This helps you to pass urine more easily.

Sometimes, more than one type of medicine is needed to control the symptoms of prostate enlargement. Dutasteride is available in combination with another medicine for prostate enlargement, called tamsulosina. The combination brand is called Combodart® and it may give quicker and better relief of symptoms than either medicine alone.

Before taking dutasteride

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking dutasteride it is important that your doctor knows:

• Se hai mai avuto una reazione allergica a un medicinale.

• Se hai problemi con il funzionamento del tuo fegato.

• Se stai assumendo o utilizzando altri medicinali. Questo include qualsiasi medicinale che stai assumendo e che è disponibile per l'acquisto senza prescrizione, così come i medicinali a base di erbe e complementari.

How to take dutasteride

• Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about dutasteride and will provide you with a full list of the side-effects which you may experience from taking it.

• Take dutasteride exactly as your doctor tells you to. Take one capsule each day. Swallow the capsule whole - do not chew or open the capsule as this could irritate your mouth.

• You can take the capsule either before or after a meal, but try to take the capsule at the same time of day each day. This will help you to remember to take your doses regularly.

• Se dimentichi di prendere una dose in tempo, prendila quando te ne ricordi. Se non te ne ricordi fino al giorno successivo, salta la dose dimenticata. Non prendere due dosi insieme per compensare una dose dimenticata.
  

Ottenere il massimo dal tuo trattamento

• Your symptoms may start to improve within a few weeks although it can take up to six months for you to notice the full benefit. This is because it takes time for the prostate gland to gradually shrink. Because of this, it is important that you continue to take the capsules regularly, even if you don't feel a benefit straightaway.

• Ricorda di mantenere i tuoi appuntamenti regolari con il tuo medico. Questo è per permettere al tuo medico di controllare i tuoi progressi.

• Considera di ridurre o interrompere la quantità di caffeina che consumi (comunemente presente in tè, caffè e cola) e alcol. Questi possono peggiorare i tuoi sintomi, quindi bere meno di queste cose potrebbe giovarti.

• Se sei un fumatore, smettere di fumare potrebbe migliorare significativamente i tuoi sintomi. Questo perché la nicotina irrita la vescica. Chiedi consiglio al tuo medico su come smettere.

• Dutasteride may cause harm to an unborn baby. Because of this, women who are pregnant should not handle these capsules if they are damaged or leaking. Also, small amounts of dutasteride will be in your semen while you are taking this medicine, and it is therefore recommended that you use a barrier method of contraception (such as a condom) if your partner could become pregnant. If you need further advice about this, speak with your pharmacist or doctor.

• If you are having an operation or any medical treatment, tell the person carrying out the treatment that you are taking dutasteride. This is because dutasteride can interfere with a blood test used to detect prostate cancer, so you must tell your doctor about taking dutasteride if you need this test.

Can dutasteride cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with dutasteride. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Se si verificano altri sintomi che ritieni possano essere dovuti al medicinale, parla con il tuo medico o farmacista per ulteriori consigli.

How to store dutasteride

• Tenere tutti i medicinali fuori dalla portata e dalla vista dei bambini.

• Conservare in un luogo fresco e asciutto, lontano da fonti di calore e luce diretta.

Informazioni importanti su tutti i medicinali