Preparazioni cutanee di clindamicina per l'acne
Dalacin T, Zindaclin
Revisione paritaria di Sid DajaniUltimo aggiornamento di Michael Stewart, MRPharmSUltimo aggiornamento 18 maggio 2023
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Clindamycin is an antibiotic - to treat acne, it is applied to the skin as a lotion, solution, or gel.
Apply the preparation to all of the affected area of skin, not just to individual spots.
The most common side-effect is mild skin irritation.
A colpo d'occhio
Clindamycin is an antibiotic skin preparation used to treat acne.
It is available as a solution, lotion, or gel.
You should apply it exactly as your doctor tells you, usually once or twice daily.
Common side effects include skin irritation, itching, dryness, or oiliness.
Consult your doctor if you experience diarrhoea while using this preparation.
About clindamycin skin preparations
Tipo di medicinale | An antibiotic skin preparation |
Utilizzato per | Acne |
Chiamato anche | Dalacin T®; Zindaclin®; Duac® Once Daily (clindamycin with benzoyl peroxide); Treclin® (clindamycin with tretinoin) |
Disponibile come | Solution, lotion and gel |
Acne is the common cause of spots. Most people with acne are aged between 12 and 25 years, but some older and younger people are affected too. Small sebaceous glands lie just under your skin surface and make an oil (sebum) that keeps your skin supple and smooth. Tiny pores on your skin allow the sebum to come on to the surface of your skin. In acne, some of these pores become blocked, causing inflamed spots.
Antibiotics like clindamycin, work by stopping bacteria that can contribute to acne from multiplying. One brand of clindamycin (Duac® Once Daily gel) also contains benzoyl peroxide, which helps to unplug blocked pores. Clindamycin is also available in combination with tretinoin in a gel called Treclin®.
Clindamycin is also available as capsules to take by mouth, and as a cream for vaginal infection. These are used for other conditions, not acne. There are two separate medicine leaflets available which provide more information about these, called Capsule di clindamicina per infezione e Crema di Clindamicina per vaginosi batterica.
Before using clindamycin skin preparations
Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start using clindamycin on your skin, it is important that your doctor knows:
If you are pregnant or breastfeeding. (Although using clindamycin lotion is not known to be harmful to an unborn baby, you should let your doctor know if you think you are pregnant.)
If you have any bowel problems which cause you to have diarrhoea.
If you have ever had an allergic reaction to a medicine or a skin preparation.
How to use clindamycin skin preparations
Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. The manufacturer's leaflet will give you more information about clindamycin, and it will also explain how to use the preparation you have been prescribed.
Apply the preparation exactly as your doctor tells you to. Wash and gently dry your skin, and then apply a thin layer to the whole of the area where your spots occur. The label on the pack will tell you how many times a day to use the preparation. Some clindamycin skin preparations are used once each day, others are used twice a day. Wash your hands well after using it.
Dalacin T® topical solution contains a small amount of alcohol which can cause stinging if it gets into grazes, or on to sensitive areas of skin. If you are using this brand of clindamycin, try to avoid getting it on areas of your skin in or around your nostrils, your eyes and your mouth.
Ottenere il massimo dal tuo trattamento
Try to keep any regular appointments with your doctor. This is so your doctor can check on your progress. A full course of treatment may last for several months.
It is recommended that you use a mild soap and lukewarm water to wash with, as very hot or cold water may worsen acne. Do not wash more than you normally do. You cannot clean off blackheads.
During your treatment your doctor may ask you to use another (non-antibiotic) skin preparation from time to time. It is important that you follow your doctor's advice, as this is to help prevent your spots from becoming resistant to treatment.
Can clindamycin skin preparations cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with clindamycin when used on the skin. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Very common clindamycin side-effects (these affect more than 1 in 10 people) | Cosa posso fare se sperimento questo? |
Skin irritation, itching, dryness or oiliness | Stop using the preparation for a day or so to allow your skin to recover. These effects usually reduce as your skin gets used to the preparation, but if they continue or become troublesome, you should speak with your doctor |
Meno comuni clindamycin side-effects (these affect fewer than 1 in 100 people) | Cosa posso fare se sperimento questo? |
Diarrea | Contact your doctor for further advice before applying any more of the preparation |
If you experience any other symptoms which you think may be due to the preparation, speak with your doctor or pharmacist.
How to store clindamycin skin preparations
Tenere tutti i medicinali fuori dalla portata e dalla vista dei bambini.
Conservare in un luogo fresco e asciutto, lontano da fonti di calore e luce diretta.
Informazioni importanti su tutti i medicinali
Informazioni importanti su tutti i medicinali
This preparation is for external use only. If someone swallows some of it, go to the accident and emergency department of your local hospital. Take the container with you, even if it is empty.
Se acquisti dei medicinali, verifica con un farmacista che siano sicuri da assumere insieme agli altri tuoi medicinali.
Se devi sottoporti a un'operazione o a un trattamento dentistico, informa la persona che esegue il trattamento su quali medicinali stai assumendo o utilizzando.
This preparation is for you. Never give it to other people, even if their condition appears to be the same as yours.
Non conservare medicinali scaduti o indesiderati. Portali alla tua farmacia locale che li smaltirà per te.
If you have any questions about this preparation, ask your pharmacist for further advice.
Segnala effetti collaterali di un medicinale o vaccino
Se si verificano effetti collaterali, è possibile segnalarli online tramite il Sito web Yellow Card.

Non sei sicuro di mescolare i medicinali?
Controlla le possibili interazioni tra farmaci, integratori e alimenti prima di assumerli insieme.
Domande frequenti
Are there different forms of clindamycin for acne?
Yes, clindamycin for acne is available as a solution, lotion, and gel. It can also be found in combination preparations, such as Duac® Once Daily gel, which includes benzoyl peroxide, and Treclin® gel, which contains tretinoin.
How do clindamycin skin preparations help with acne?
Clindamycin is an antibiotic that works by stopping the proliferation of bacteria that contribute to acne. Some combination products, like Duac® Once Daily gel, also contain ingredients (benzoyl peroxide) that help to unblock pores.
What should I do if I am pregnant or breastfeeding and considering using clindamycin skin preparations?
It's important to inform your doctor if you are pregnant or breastfeeding. While using clindamycin lotion is not known to be harmful to an unborn baby, your doctor needs to be aware of your situation.
When should I apply clindamycin skin preparations?
You should apply the preparation exactly as instructed by your doctor. Typically, you wash and gently dry your skin, then apply a thin layer to the entire area affected by spots. The frequency of application (once or twice daily) will be indicated on the product label and by your doctor. Always remember to wash your hands well after applying it.
Can clindamycin skin preparations be used for other types of infections?
While clindamycin is an antibiotic, the skin preparations discussed are specifically for acne. Clindamycin also comes in capsules for oral use and a cream for vaginal infections, but these forms are used for different conditions and not for acne.
Ulteriori letture e riferimenti
- Manufacturer's PIL, Dalacin® T Topical Solution/Topical Lotion; Pfizer Limited, The electronic Medicines Compendium. Dated February 2021.
- Medicinali Completi BNF 89ª Edizione; Associazione Medica Britannica e Società Farmaceutica Reale di Gran Bretagna, Londra.
Informazioni sull'autoreVisualizza il profilo completo

Michael Stewart, MRPharmS
Responsabile Revisione Foglietti Illustrativi – Contrattista, Farmacista
BPharm (Hons), MRPharmS
Michael è un farmacista comunitario che esercita nelle Midlands e nel South Yorkshire con oltre 20 anni di esperienza nel consigliare su farmaci e condizioni mediche. Ha una solida esperienza nella formazione sanitaria, avendo prodotto e tenuto corsi di formazione per team di farmacia e personale di strutture di assistenza residenziale, inclusi infermieri. Ha anche contribuito a consigli consultivi farmaceutici per la gestione di condizioni a bassa gravità nella comunità.
Informazioni sul recensore

Sid Dajani
Sultan Dajani si è laureato alla London School of Pharmacy nel 1994 ed è diventato il più giovane membro eletto del consiglio della Royal Pharmaceutical Society dalla sua fondazione nel 1842.
Storia dell'articolo
Le informazioni su questa pagina sono scritte e revisionate da clinici qualificati.
Articolo disponibile anche in Inglese, Tedesco, Spagnolo, Francese, Italiano, Portoghese, Hindi, Ebraico, Arabo, and Svedese.
Prossima revisione prevista: 17 Nov 2027
18 maggio 2023 | Ultima versione

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