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Buserelin for men

Suprefact

Buserelin (brand name Suprefact®) is a hormone treatment for men with prostate cancer who have not had surgery to remove the testicles.

Each time you collect your prescription for buserelin, check to make sure the brand name is Suprefact®. This is because there is another brand of buserelin nasal spray available, which is not suitable for you.

Use one spray into each nostril six times each day.

About buserelin for men

Tipo di medicinale

A gonadorelin analogue

Utilizzato per

Cancro alla prostata

Chiamato anche

Suprefact®

Disponibile come

Injection and nasal spray

Although in many cases cancro alla prostata is slow-growing, in some men it can be more aggressive and spread to other parts of the body. When this happens, there can be a benefit from using a hormone treatment, such as buserelin, which slows the progress of the cancer.

Prostate cancer cells need the male hormone testosterone to grow. Buserelin works by reducing the production of testosterone and this helps to stop the growth of the cancer cells.

Buserelin is also used in some disorders which affect women. There is a separate medicine leaflet called Buserelin for women che fornisce ulteriori informazioni su questo.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start using buserelin it is important that your doctor knows:

  • If you have low moods or are depressed.

  • Se hai la pressione alta (ipertensione).

  • If you have diabetes (diabetes mellitus).

  • If you have a bone disease such as osteoporosis.

  • Se stai assumendo o utilizzando altri medicinali. Questo include qualsiasi medicinale che stai assumendo e che è disponibile per l'acquisto senza prescrizione, così come i medicinali a base di erbe e complementari.

  • Se hai mai avuto una reazione allergica a un medicinale.

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  • Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about buserelin and will provide you with a full list of the side-effects which you could experience.

  • When you start buserelin, you will be given injections every eight hours for the first seven days. For convenience, these injections are likely to be given to you while you are in hospital. On the next day, you will be given a nasal spray to use. You must follow the instructions given to you by your doctor for using the spray, but it is usually recommended that you use one spray into each nostril six times each day as follows:

  • 1st dose before your breakfast.

  • 2nd dose after your breakfast.

  • 3rd dose before your midday meal.

  • 4th dose after your midday meal.

  • 5th dose before your evening meal.

  • 6th dose after your evening meal.

  • Each time you open a new bottle, you will need to attach the nebuliser to the bottle of solution and then 'prime' the spray. You do this by pumping the spray about six or seven times until you see a fine spray produced. Priming fills the nebuliser and tests that the spray is working correctly.

  • It is important that you use this medicine regularly and space the doses out evenly through the day. If you forget to take a dose at your usual time, take it as soon as you remember. If it is almost time for your next dose then skip the forgotten dose and take your next dose when it is due. Do not take two doses together to make up for a forgotten dose.

  • About 1 in 10 men notice that their symptoms (usually pain) become worse for a short while when they first start treatment with buserelin. Your doctor is likely to give you some tablets to take during the first few weeks to help prevent this. If you do experience any increase in pain, this will settle again after a couple of weeks.

  • Please keep your appointments with your doctor so that your progress can be monitored. Your doctor will want you to have regular blood tests to check your hormone levels.

  • Even if you get a cold or your nose feels blocked, you should continue to use the spray as it will still work. If you are using any other nasal sprays (such as decongestants), you should use buserelin spray first, then wait at least 30 minutes after using buserelin before using the other nasal spray.

  • Buserelin can affect your blood sugar levels. If you have diabetes you may need to check your blood glucose more frequently. Your doctor will advise you about this.

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with buserelin. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Common buserelin side-effects (these affect fewer than 1 in 10 men)

Cosa posso fare se sperimento questo?

Feeling dizzy, tired, or sleepy

If this happens, do not drive and do not use tools or machines while affected

Feeling sick (nausea) or being sick (vomiting), stomach or tummy (abdominal) pain

Attieniti a cibi semplici - evita pasti ricchi o piccanti

Diarrea

Bevi molta acqua per reintegrare i liquidi persi

Costipazione

Eat a well-balanced diet and drink several glasses of water each day

Headache, muscle pain and stiffness

Chiedi al tuo farmacista di consigliare un antidolorifico adatto

Irritation of your nose or throat, nosebleeds, changes in the way things smell and taste, changes in your weight, feeling nervous or depressed, disturbed sleep, being aware of a fast heartbeat, dry skin, acne, changes in the thickness of your hair

Se uno di questi diventa problematico, parla con il tuo medico

Importante: In rare cases this medicine may cause a serious allergic reaction. Seek urgent medical attention if you develop a red, itchy skin rash and any difficulties with your breathing, including swelling of the face, lips or tongue. Taking an antihistamine may help slow the reaction whilst you are waiting for treatment.

If you experience any other symptoms which you think may be due to buserelin, please speak with your doctor or pharmacist for further advice.

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  • Tenere tutti i medicinali fuori dalla portata e dalla vista dei bambini.

  • Conservare in un luogo fresco e asciutto, lontano da fonti di calore e luce diretta.

  • Each bottle of nasal spray contains one week of treatment. Even if there is some solution left after using the spray for a week, please do not use it. Instead, open a fresh bottle.

Informazioni importanti su tutti i medicinali

Se acquisti dei medicinali, verifica con un farmacista che siano sicuri da assumere insieme agli altri tuoi medicinali.

Non assumere mai più della dose prescritta. Se sospetti che tu o qualcun altro possa aver assunto un sovradosaggio di questo medicinale, recati al pronto soccorso del tuo ospedale locale. Porta con te il contenitore, anche se è vuoto.

Se devi sottoporti a un'operazione o a un trattamento dentistico, informa la persona che esegue il trattamento sui medicinali che stai assumendo.

Questo medicinale è per te. Non darlo mai ad altre persone, anche se la loro condizione sembra essere la stessa della tua.

Non conservare medicinali scaduti o indesiderati. Portali alla tua farmacia locale che li smaltirà per te.

Se hai domande su questo medicinale, chiedi al tuo farmacista.

Segnala effetti collaterali di un medicinale o vaccino

Se si verificano effetti collaterali, è possibile segnalarli online tramite il sito web Yellow Card.

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Ulteriori letture e riferimenti

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Storia dell'articolo

Le informazioni su questa pagina sono scritte e revisionate da clinici qualificati.

  • Next review due: 3 Sept 2027
  • 14 Sept 2024 | Ultima versione

    Ultimo aggiornamento di

    Michael Stewart, MRPharmS

    Revisione paritaria di

    Sid Dajani
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