Methyldopa for high blood pressure
Aldomet
Revisione paritaria di Sid DajaniUltimo aggiornamento di Michael Stewart, MRPharmSUltimo aggiornamento 15 Gen 2025
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Take methyldopa at the same times each day. It is usual to be prescribed two or three doses to take a day.
Methyldopa can make you feel sleepy, particularly during the first two or three days. Do not drive and do not use tools or machines while affected.
Continue to take methyldopa tablets until you are advised otherwise by your doctor.
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About methyldopa
Tipo di medicinale | Un farmaco antipertensivo ad azione centrale |
Utilizzato per | Alta pressione sanguigna (ipertensione) |
Chiamato anche | Aldomet® |
Disponibile come | Compresse |
Most people with pressione alta (ipertensione) do not feel unwell, but it is important that your high blood pressure is treated even if you feel fine. This is because high blood pressure can be damaging to your blood vessels and can put a strain on your heart. By lowering your blood pressure, methyldopa reduces your cardiovascular risk.
Methyldopa is one of the medicines of choice for treating high blood pressure in pregnancy. When taken during pregnancy, treatment with methyldopa is reviewed soon after the birth of the baby, as other treatment options are then likely to be more suitable.
Before taking methyldopa
Torna ai contenutiSome medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking methyldopa it is important that your doctor knows:
Se hai problemi con il funzionamento del tuo fegato, o problemi con il funzionamento dei tuoi reni.
Se hai mai avuto una malattia depressiva.
If you have been told you have any of the following rare conditions: an adrenaline-producing growth called a phaeochromocytoma or a paraganglioma, or an inherited blood disorder called porphyria.
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Se hai mai avuto una reazione allergica a un medicinale.
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How to take methyldopa
Torna ai contenutiBefore you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about methyldopa and will provide you with a full list of the side-effects which you may experience from taking it.
Take methyldopa exactly as your doctor tells you to. It is usual to start by taking 250 mg two or three times daily. Your doctor may increase your dose after a few days if it is necessary. Each time you see your doctor you will be told how many tablets to take for each dose, and this information will also be printed on the label of the pack of tablets to remind you about what the doctor said to you.
Try to take your doses at the same times of day each day, as this will help you to remember to take them regularly. You can take your doses either before or after food. Swallow the tablet with a drink of water.
Se dimentichi di prendere una dose, prendila appena te ne ricordi. Cerca di assumere il numero corretto di dosi ogni giorno, ma non prendere due dosi contemporaneamente per compensare una dose dimenticata.
Ottenere il massimo dal tuo trattamento
Torna ai contenutiTry to keep your regular appointments with your doctor so your progress can be monitored. Your doctor will want you to have blood tests from time to time to make sure your liver is working properly.
There are three strengths of methyldopa tablet available - 125 mg, 250 mg and 500 mg. Each time you collect a fresh supply of tablets it is a good idea to check to make sure you receive the strength you are expecting. If you have any questions, please ask your pharmacist to advise you.
Il tuo medico potrebbe darti consigli dietetici e sullo stile di vita riguardo a mangiare in modo sano, non fumare e fare esercizio fisico regolare. In tal caso, è importante che segui i consigli che ti vengono dati.
Drinking alcohol while you are on methyldopa is not recommended. It can increase the chance that you will experience side-effects, such as feeling sleepy or dizzy.
If you buy any medicines 'over the counter', please check with a pharmacist that they are suitable for you to take with methyldopa. Some medicines, such as some anti-inflammatory painkillers, can interfere with the way methyldopa works.
If you are due to have an operation or dental treatment, tell the person carrying out the treatment that you are taking methyldopa. This is because some anaesthetics can affect your blood pressure. Also, before having any medical tests, tell the person carrying out the test that you are taking methyldopa, as the results of some tests can be affected by it.
Continue to take methyldopa tablets until you are advised otherwise by your doctor.
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Can methyldopa cause problems?
Torna ai contenutiAlong with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the common ones associated with methyldopa. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Common methyldopa side-effects | Cosa posso fare se sperimento questo? |
Feeling sleepy, weak, or tired | This can happen during the first few days of treatment and if your dose is increased. Increase your evening dose first. Do not drive and do not use tools or machines while affected. Do not drink alcohol |
Mal di testa | Bevi molta acqua e chiedi al tuo farmacista di consigliarti un antidolorifico adatto. Se i mal di testa persistono, informa il tuo medico |
Importante: if you develop a high temperature which you can't explain, or if you notice any yellowing of your skin or of the whites of your eyes (jaundice), speak with your doctor as soon as possible. Occasionally, some people taking methyldopa have had blood or liver problems and your doctor will want you to have a blood test to check for these.
Se si verificano altri sintomi che ritieni possano essere dovuti alle compresse, parla con il tuo medico o farmacista per ulteriori consigli.
How to store methyldopa
Torna ai contenutiTenere tutti i medicinali fuori dalla portata e dalla vista dei bambini.
Conservare in un luogo fresco e asciutto, lontano da fonti di calore e luce diretta.
Informazioni importanti su tutti i medicinali
Torna ai contenutiInformazioni importanti su tutti i medicinali
Non assumere mai più della dose prescritta. Se sospetti che tu o qualcun altro possa aver assunto un sovradosaggio di questo medicinale, recati al pronto soccorso del tuo ospedale locale. Porta con te il contenitore, anche se è vuoto.
Questo medicinale è per te. Non darlo mai ad altre persone, anche se la loro condizione sembra essere la stessa della tua.
Non conservare medicinali scaduti o indesiderati. Portali alla tua farmacia locale che li smaltirà per te.
Se hai domande su questo medicinale, chiedi al tuo farmacista.
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Ulteriori letture e riferimenti
- Manufacturer's PIL, Aldomet® Tablets 250 mg and 500 mg; Aspen Pharma Trading Ltd, The electronic Medicines Compendium. Dated April 2022.
- Medicinali Completi BNF 89ª Edizione; Associazione Medica Britannica e Società Farmaceutica Reale di Gran Bretagna, Londra.
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About the authorView full bio

Michael Stewart, MRPharmS
Medicine Leaflet Review Manager – Contractor, Pharmacist
BPharm (Hons), MRPharmS
Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.
About the reviewer

Sid Dajani
Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.
Storia dell'articolo
Le informazioni su questa pagina sono scritte e revisionate da clinici qualificati.
Prossima revisione prevista: 15 Gen 2028
15 Gen 2025 | Ultima versione

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