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Compresse di Eplerenone

Inspra

Take eplerenone tablets once a day.

Do not use salt substitutes while you are taking eplerenone.

Make sure your doctor knows about any other medicines you are taking alongside eplerenone.

A colpo d'occhio

  • Eplerenone is a medicine for people with heart failure that affects the left side of their heart.

  • It helps prevent heart failure from worsening by blocking a substance called aldosterone.

  • You typically take one tablet daily, which may increase in strength over a few weeks.

  • Your doctor will monitor your blood potassium levels regularly with blood tests.

  • Common side-effects include feeling dizzy, headache, feeling sick, diarrhoea, or constipation.

  • If you feel dizzy, avoid driving or operating machinery.

  • If you have kidney or liver problems, high potassium levels, or are pregnant, tell your doctor.

About eplerenone

Tipo di medicinale

An aldosterone antagonist

Utilizzato per

Insufficienza cardiaca

Chiamato anche

Inspra®

Disponibile come

Compresse

Insufficienza cardiaca means that your heart is not functioning as well as it should. In a healthy heart, a set amount of blood enters the heart during each heartbeat and is pumped out again. If you have heart failure, your heart cannot cope with pumping the full amount of blood in each heartbeat.

If you have heart failure which affects the left ventricle of your heart (left-sided heart failure), it can cause you to be short of breath. It can also be associated with a cough. This is generally worse when you are active (for example, walking uphill) or when you are lying flat in bed.

Eplerenone is prescribed alongside other medicines to help prevent worsening of heart failure in people who have left-sided heart failure. It works by blocking the action of a substance in your body called aldosterone. High levels of aldosterone can cause changes that result in heart failure. By blocking aldosterone, eplerenone helps prevent heart failure from worsening.

Before taking eplerenone

Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking eplerenone it is important that your doctor knows:

  • If you have any problems with the way your kidneys work, or if you have any problems with the way your liver works.

  • If you have been told you have high levels of potassium in your blood.

  • Se sei incinta, stai cercando di avere un bambino o stai allattando.

  • Se stai assumendo altri medicinali. Questo include qualsiasi medicinale che stai assumendo e che è disponibile per l'acquisto senza prescrizione medica, così come i medicinali a base di erbe e complementari.

  • Se hai mai avuto una reazione allergica a un medicinale.

How to take eplerenone

  • Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about eplerenone, and it will also provide you with a full list of the side-effects which you could experience from taking it.

  • Take eplerenone exactly as your doctor tells you to. You will be prescribed one tablet to take every day. There are two strengths of tablet - you will be prescribed the lower-strength (25 mg) tablet to begin with, but this will be increased to the 50 mg strength tablet within a few weeks.

  • Swallow the tablet whole with a drink of water. You can take eplerenone either with or without food.

  • Unless your doctor tells you otherwise, you can generally take eplerenone at a time of day you find easy to remember. It is best, however, to try to take the tablets at the same time of day each day, as this will help you to remember to take your doses regularly.

  • If you forget to take a dose, take one as soon as you remember, if this is during the same day as your dose was due. If you do not remember until the following day, leave out the forgotten dose from the previous day and take the dose that is due as normal. Do not take two doses at the same time to make up for a missed dose.

Ottenere il massimo dal tuo trattamento

  • Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress. The salt balance in your bloodstream may be upset by eplerenone and your doctor will want you to have a blood test from time to time to check the amount of potassium in your blood.

  • Try to avoid things with a high potassium content, such as 'salt substitutes'. This is so the level of potassium in your body does not become too high.

  • For most people with heart failure, regular exercise is advised. The healthier the heart, the better it will pump. The level of exercise recommended varies from person to person, so before you start to exercise, get the go-ahead from your doctor.

  • Your doctor may advise you to make some lifestyle changes, like losing weight if you are overweight, reducing the amount of alcohol you drink, and stopping smoking. Following this advice will help to improve the health of your heart.

  • If you buy any medicines 'over the counter', check with a pharmacist that they are suitable to take with your prescribed medicines. This is because some painkillers called non-steroidal anti-inflammatory drugs (NSAIDs) may not be recommended for you.

  • Se devi sottoporti a un'operazione o a un trattamento dentale, informa la persona che esegue il trattamento quali medicinali stai assumendo.

  • Treatment with eplerenone is usually long-term, so continue to take the tablets regularly until you are advised otherwise by your doctor.

Can eplerenone cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the more common ones associated with eplerenone. The best place to find a full list of the side-effects which can be associated with your medicine, is from the manufacturer's printed information leaflet supplied with the medicine. Alternatively, you can find an example of a manufacturer's information leaflet in the reference section below. Speak with your doctor or pharmacist if any of the following continue or become troublesome.

Common

eplerenone side-effects (these affect fewer than 1 in 10 people)

Cosa posso fare se sperimento questo?

Feeling dizzy or light-headed

If you begin to feel dizzy, lie down so that you do not faint, then sit for a few moments before standing. Do not drive and do not use tools or machines while affected. If this continues, speak with your doctor

Mal di testa

Bevi molta acqua e chiedi al tuo farmacista di consigliarti un antidolorifico adatto. Se i mal di testa persistono, consulta il tuo medico

Sensazione di nausea

Stick to simple foods - avoid fatty or spicy meals. If this continues, speak with your doctor

Diarrea

Bevi molta acqua per reintegrare i liquidi persi. Se questo continua, parla con il tuo medico

Costipazione

Segui una dieta equilibrata e bevi diversi bicchieri d'acqua ogni giorno

Cough, itchy skin rash, kidney problems, muscle spasms, sleeping problems, back pain

Se problematico, parla con il tuo medico

Changes to blood tests (such as high blood potassium and high blood cholesterol)

Il tuo medico controllerà questo

Se si verificano altri sintomi che ritieni possano essere dovuti alle compresse, parla con il tuo medico o farmacista per ulteriori consigli.

How to store eplerenone

  • Tenere tutti i medicinali fuori dalla portata e dalla vista dei bambini.

  • Conservare in un luogo fresco e asciutto, lontano da fonti di calore e luce diretta.

Informazioni importanti su tutti i medicinali

Informazioni importanti su tutti i medicinali

Non assumere mai più della dose prescritta. Se sospetti che tu o qualcun altro possa aver assunto un sovradosaggio di questo medicinale, recati al pronto soccorso del tuo ospedale locale. Porta con te il contenitore, anche se è vuoto.

Questo medicinale è per te. Non darlo mai ad altre persone, anche se la loro condizione sembra essere la stessa della tua.

Non conservare medicinali scaduti o indesiderati. Portali alla tua farmacia locale che li smaltirà per te.

Se hai domande su questo medicinale, chiedi al tuo farmacista.

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Domande frequenti

What is the typical starting dose for eplerenone and how might it change?

You will usually start with a 25 mg tablet once a day. Your doctor will likely increase this to a 50 mg tablet daily within a few weeks, depending on your condition and how you respond to the medication.

Are there any specific foods or supplements I should avoid while taking eplerenone?

Yes, you should try to avoid products with a high potassium content, including 'salt substitutes'. This is because eplerenone can affect the potassium levels in your blood, and your doctor will monitor this with blood tests.

Does eplerenone need to be taken with or without food?

You can take eplerenone either with or without food, whichever is most convenient for you. It's generally best to try and take it at the same time each day to help you remember your dose.

What should I do if I accidentally miss a dose of eplerenone?

If you remember on the same day that you missed your dose, take it as soon as you recall. However, if you don't remember until the next day, simply skip the missed dose and continue with your regular schedule. Never take two doses at once to make up for a forgotten one.

How long will I need to take eplerenone?

Treatment with eplerenone is typically long-term. You should continue taking the tablets regularly unless your doctor specifically advises you to stop.

How should I store my eplerenone tablets?

Keep eplerenone out of the sight and reach of children. Store it in a cool, dry place, away from direct heat and light.

Can I take 'over the counter' medicines with eplerenone?

If you plan to buy any medicines without a prescription, it's important to check with a pharmacist first. This is because some common painkillers, like non-steroidal anti-inflammatory drugs (NSAIDs), might not be recommended for you while taking eplerenone.

Ulteriori letture e riferimenti

Informazioni sull'autoreVisualizza il profilo completo

Immagine dell'autore

Michael Stewart, MRPharmS

Responsabile Revisione Foglietti Illustrativi – Contrattista, Farmacista

BPharm (Hons), MRPharmS

Michael è un farmacista comunitario che esercita nelle Midlands e nel South Yorkshire con oltre 20 anni di esperienza nel consigliare su farmaci e condizioni mediche. Ha una solida esperienza nella formazione sanitaria, avendo prodotto e tenuto corsi di formazione per team di farmacia e personale di strutture di assistenza residenziale, inclusi infermieri. Ha anche contribuito a consigli consultivi farmaceutici per la gestione di condizioni a bassa gravità nella comunità.

Informazioni sul recensore

Immagine dell'autore

Sid Dajani

Sultan Dajani si è laureato alla London School of Pharmacy nel 1994 ed è diventato il più giovane membro eletto del consiglio della Royal Pharmaceutical Society dalla sua fondazione nel 1842.

Storia dell'articolo

Le informazioni su questa pagina sono scritte e revisionate da clinici qualificati.

  • Prossima revisione prevista: 23 Ago 2027
  • 24 Feb 2023 | Ultima versione

    Ultimo aggiornamento di

    Michael Stewart, MRPharmS

    Revisione paritaria di

    Sid Dajani
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