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Macrogol per la stitichezza o la pulizia intestinale

CosmoCol, Movicol, Laxido

Carefully follow the printed information given with the preparation.

Mix the contents of the sachet into water before taking.

Common side-effects include feeling sick (nausea) and tummy (abdominal) discomfort or pain.

A colpo d'occhio

  • Macrogols are osmotic laxatives used to treat constipation or clear the bowel.

  • They work by drawing water into the bowel to soften stools.

  • For constipation, macrogols like Movicol and Laxido are available in sachets or liquid.

  • For bowel cleansing, macrogols like Klean-Prep are used before procedures.

  • Common side-effects can include tummy pain, wind, and nausea.

  • Always follow the preparation and dosage instructions carefully.

About macrogols

Tipo di medicinale

Osmotic laxative and bowel cleansing solution

Utilizzato per

Constipation; to evacuate the bowel before investigation or surgery

Chiamato anche

For constipation: CosmoCol®; Movicol®; Laxido®; Molaxole®; Strigol®
For bowel cleansing
: Klean-Prep®, Moviprep®

Disponibile come

Sachets of powder or oral liquid medicine

Macrogols belong to a group of medicines known as osmotic laxatives. They are substances which are used medically to relieve constipation or to clear the bowel before some clinical procedures. They are sometimes called polyethylene glycols. Macrogols are identified by a number which represents their molecular weight so, for example, the macrogol used to relieve constipation is called macrogol '3350'.

Constipation is a common problem which can be caused by a number of things. Not eating enough fibre or not drinking enough fluid can cause constipation. Some conditions (such as pregnancy) can cause constipation, as can a lack of exercise or movement (such as being ill in bed) and some medicines. Macrogols relieve constipation by drawing water into your bowel to soften your stools, making them easier to pass.

Bowel cleansing solutions also contain macrogol '3350' although they are not treatments for constipation. They are used to ensure that the bowel is free of solid contents before a bowel examination or surgical procedure.

Before taking macrogols

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start the treatment it is important that your doctor or pharmacist knows:

  • Se sei incinta o stai allattando.

  • If you have any bowel problems other than constipation, such as Crohn's disease, ulcerative colitis or toxic megacolon.

  • Se hai una condizione cardiaca.

  • Se hai mai avuto una reazione allergica a un medicinale.

  • If you use starch-based food-thickeners to help with difficulty swallowing.

  • Se stai assumendo altri medicinali. Questo include qualsiasi medicinale che stai assumendo e che è disponibile per l'acquisto senza prescrizione medica, così come i medicinali a base di erbe e complementari.

  • If the treatment is intended for a child. This is because laxatives should solo be given to children on the advice of a doctor or healthcare professional.

How to take macrogols

Before starting the treatment, read the manufacturer's printed information leaflet from inside the pack. It will tell you how to prepare your dose and how long the solution can be kept for after preparation. Once mixed with water, the solution should be kept in the fridge. Do not use any solution remaining after the time recommended in the manufacturer's instructions.

If taking for constipation (brands CosmoCol®, Movicol®, Laxido®, Molaxole®)

  • Your doctor will tell you how many sachets to take for each dose. A daily dose can range from 1-2 sachets daily, up to a maximum of 8 sachets daily. Unless the directions say otherwise, stir the contents of each sachet into half a glass of water (100-125 ml) before taking.

If taking for bowel cleansing (brands Klean-Prep®, Moviprep®)

  • You will be given written instructions from the clinic that will tell you how many sachets to make up into a solution, and when you should start to drink it. It is important that you follow the directions carefully.

  • You will also be given written instructions about what food or drink you can, or cannot, have until after the procedure is completed. Typically, the advice is to not eat any solid food from about two hours before you start drinking the solution. Again, it is important that you carefully follow the directions you are given.

  • The treatment can interfere with the absorption of medicines taken at the same time. If you take medication regularly, please ask your doctor about when to take your other medicines.

Ottenere il massimo dal tuo trattamento

If taking for constipation

  • Una dieta sana ricca di fibre (pane e cereali integrali, crusca, frutta e verdure a foglia verde), accompagnata da diversi bicchieri d'acqua ogni giorno e esercizio fisico quotidiano, è importante per mantenere una funzione intestinale sana.

  • You can read more about how to prevent or treat constipation in the separate condition leaflets called Costipazione (for adults) and Costipazione nei Bambini.

If taking for bowel cleansing

  • The preparation will start to work after an hour or two, so stay near to a toilet while you are taking the solution.

  • If you have any questions about the treatment, contact the hospital department where you are receiving the treatment for further advice.

Can macrogols cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with macrogol '3350'. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Common

macrogol '3350' side-effects


Cosa posso fare se sperimento questo?

Tummy (abdominal) pain, wind (flatulence), feeling sick (nausea)

These effects do not usually last for long. Drinking the solution more slowly may help

Se si verificano altri sintomi che ritieni possano essere dovuti al medicinale, parla con il tuo medico o farmacista per ulteriori consigli.

How to store macrogols

  • Tenere tutti i medicinali fuori dalla portata e dalla vista dei bambini.

  • Conservare in un luogo fresco e asciutto, lontano da fonti di calore e luce diretta.

Informazioni importanti su tutti i medicinali

Informazioni importanti su tutti i medicinali

Non assumere mai più della dose prescritta. Se sospetti che tu o qualcun altro possa aver assunto un sovradosaggio di questo medicinale, recati al pronto soccorso del tuo ospedale locale. Porta con te il contenitore, anche se è vuoto.

Questo medicinale è per te. Non darlo mai ad altre persone, anche se la loro condizione sembra essere la stessa della tua.

Se devi sottoporti a un'operazione o a un trattamento dentale, informa la persona che esegue il trattamento sui medicinali che stai assumendo.

Se acquisti dei medicinali, verifica con un farmacista che siano adatti da assumere insieme agli altri tuoi medicinali.

Non conservare medicinali scaduti o indesiderati. Portali alla tua farmacia locale che li smaltirà per te.

Se hai domande su questo medicinale, chiedi al tuo farmacista.

Segnala effetti collaterali di un medicinale o vaccino

Se si verificano effetti collaterali, è possibile segnalarli online tramite il Sito web Yellow Card.

verificatore di sintomi

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Controlla le possibili interazioni tra farmaci, integratori e alimenti prima di assumerli insieme.

Domande frequenti

Can macrogol 3350 be used for long-term constipation relief?

The article states that a healthy diet, sufficient water, and daily exercise are important for healthy bowel function when taking macrogols for constipation, indicating they are part of an ongoing management strategy. It doesn't specify a time limit for using them for constipation relief.

What is the difference between macrogol '3350' and other types of macrogol?

Macrogols are identified by a number representing their molecular weight. Macrogol '3350' is the specific type used to relieve constipation and in bowel cleansing solutions. The article does not detail other types of macrogols or their uses.

Are there any specific situations where macrogols should be avoided?

Macrogols should be used with caution, and a doctor or pharmacist should be consulted, if you are pregnant or breastfeeding, have bowel problems other than constipation (such as Crohn's disease or ulcerative colitis), have a heart condition, have had a previous allergic reaction to a medicine, use starch-based food-thickeners, or if the treatment is for a child, as laxatives for children should only be given under medical advice.

How should I prepare macrogol solution for use?

For constipation, stir the contents of each sachet into half a glass of water (100-125 ml) before taking. For bowel cleansing, you will receive specific written instructions from your clinic on how to prepare the solution. In both cases, once mixed, the solution should be kept in the fridge, and any remaining solution after the manufacturer's recommended time should not be used.

Can macrogols interact with other medications I am taking?

Yes, for bowel cleansing, macrogol treatment can interfere with the absorption of other medicines taken at the same time. If you take medication regularly, you should ask your doctor about when to take your other medicines. For constipation, the article advises checking with a pharmacist if buying any other medicines to ensure they are suitable to take with macrogols.

Ulteriori letture e riferimenti

Informazioni sull'autoreVisualizza il profilo completo

Immagine dell'autore

Michael Stewart, MRPharmS

Responsabile Revisione Foglietti Illustrativi – Contrattista, Farmacista

BPharm (Hons), MRPharmS

Michael è un farmacista comunitario che esercita nelle Midlands e nel South Yorkshire con oltre 20 anni di esperienza nel consigliare su farmaci e condizioni mediche. Ha una solida esperienza nella formazione sanitaria, avendo prodotto e tenuto corsi di formazione per team di farmacia e personale di strutture di assistenza residenziale, inclusi infermieri. Ha anche contribuito a consigli consultivi farmaceutici per la gestione di condizioni a bassa gravità nella comunità.

Informazioni sul recensore

Immagine dell'autore

Sid Dajani

Sultan Dajani si è laureato alla London School of Pharmacy nel 1994 ed è diventato il più giovane membro eletto del consiglio della Royal Pharmaceutical Society dalla sua fondazione nel 1842.

Storia dell'articolo

Le informazioni su questa pagina sono scritte e revisionate da clinici qualificati.

  • Next review due: 4 Oct 2026
  • 5 Oct 2023 | Ultima versione

    Ultimo aggiornamento di

    Michael Stewart, MRPharmS

    Revisione paritaria di

    Sid Dajani
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