Crema di aciclovir
Lipsore, Virasorb, Zovirax
Revisione paritaria di Sid DajaniUltimo aggiornamento di Michael Stewart, MRPharmSUltimo aggiornamento 5 Nov 2024
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Use aciclovir cream five times a day for at least five days.
To avoid spreading the infection, wash your hands before and after applying aciclovir. Remember infection can also spread to others.
Do not share the same tube of cream with other people.
A colpo d'occhio
Aciclovir cream is an antiviral medicine used to treat cold sores and genital herpes.
It works by preventing the herpes simplex virus from multiplying.
Start using the cream at the first sign of infection and apply it five times a day.
Wash your hands before and after applying the cream to prevent spreading the infection.
The cream should not be used in your mouth, vagina, or near your eyes.
Seek medical advice if you are pregnant or have a weakened immune system.
About aciclovir cream
Tipo di medicinale | An antiviral cream |
Utilizzato per | Treatment of cold sores and genital herpes |
Chiamato anche | Acyclovir (in US); Lipsore®; Virasorb®; Zovirax® |
Disponibile come | Crema |
Aciclovir is an antiviral agent. It works by attacking the herpes simplex virus, of which there are two types:
Type 1 herpes simplex virus is the usual cause of herpes labiale around the mouth. It also causes up to half of the cases of genital herpes.
Type 2 herpes simplex virus usually only causes herpes genitale. It can sometimes cause cold sores.
Aciclovir does not kill the herpes simplex virus, but it does prevent it from multiplying. This means that, although it may have little effect on existing blisters, it can prevent them from getting worse. If you use aciclovir cream as soon as your symptoms start then it will reduce the severity and duration of the symptoms. Aciclovir cream is available on prescription for the treatment of cold sores and genital herpes infections. You can also buy some brands without a prescription in order to treat cold sores.
There are other preparations of aciclovir available which are not dealt with by this medicine leaflet. See the separate leaflets called Aciclovir per infezioni virali e Pomata oculare di aciclovir for more information about other formulations of aciclovir.
Before using aciclovir cream
To make sure that this is the right treatment for you, before you start using aciclovir cream it is important that your doctor or pharmacist knows:
If you are pregnant. This is because, if you are expecting a baby, medicines should only be used on the advice of a doctor.
If your immune system is not working as well as it should (for instance, if you have HIV or AIDS). This is because you may need additional antiviral treatment.
Se stai assumendo o utilizzando altri medicinali. Questo include qualsiasi medicinale che stai assumendo e che è disponibile per l'acquisto senza prescrizione, così come i medicinali a base di erbe e complementari.
If you have ever had an allergic reaction to a medicine or skin product.
How to apply aciclovir cream
Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about using aciclovir cream and will provide you with a full list of the side-effects which you could experience from using it.
Apply the cream five times a day. The best way to do this is to use it every four hours during the day (suggested times are 7 am, 11 am, 3 pm, 7 pm and 11 pm). Dab the cream on to the area rather than rubbing it in. This will minimise any damage to the blisters, which could cause pain and spread the virus around.
Start using the cream at the first sign of infection (for instance, when you first feel your skin tingling) and continue to use it for five days. This is often sufficient time for the sore to heal but you can continue to use the cream for a further five days if needed. Remember to wash and dry your hands before and after using aciclovir, to prevent spreading any infection.
If you forget to use the cream, apply it as soon as you remember and then continue using it again at your usual times.
Ottenere il massimo dal tuo trattamento
Try to keep the areas affected by blisters as clean and dry as possible and only touch the sores when you apply the cream.
Aciclovir cream is not intended for use in your mouth or vagina, or near your eyes. This is because it may irritate these parts of your body. If you have sores in any of these areas, you should make an appointment to see your doctor, as alternative preparations can be prescribed which will be suitable for you to use.
When you have a cold sore you should not kiss anyone or allow anyone to come into skin contact with the sore. In particular, avoid kissing newborn babies and anyone who has a poor immune system. When you have no symptoms, you are not usually infectious.
Genital herpes simplex virus is very contagious when blisters are present. You should not have sex from the time your symptoms first start until they are fully over, as there is a high chance of passing on the virus.
Can aciclovir cream cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the ones associated with creams containing aciclovir. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Aciclovir cream side-effects (these affect fewer than 1 in 10 people) | Cosa posso fare se sperimento questo? |
Flaking, itchy or dry skin, burning or stinging when applying the cream | These effects do not usually last for long but if any become troublesome speak with your doctor or pharmacist |
Se si verificano altri sintomi che ritieni possano essere dovuti alla crema, ti preghiamo di consultare il tuo medico o farmacista per ulteriori consigli.
How to store aciclovir cream
Tenere tutti i medicinali fuori dalla portata e dalla vista dei bambini.
Conservare in un luogo fresco e asciutto, lontano da fonti di calore e luce diretta.
Check the label to see how long the cream can be kept once the pack has been opened.
Informazioni importanti su tutti i medicinali
Informazioni importanti su tutti i medicinali
This preparation is for use on the skin only. If you suspect that someone has swallowed some of it by accident, contact the accident and emergency department of your local hospital for advice.
Se devi sottoporti a un'operazione o a un trattamento dentistico, informa la persona che esegue il trattamento sui medicinali che stai assumendo.
Questo medicinale è per te. Non darlo mai ad altre persone, anche se la loro condizione sembra essere la stessa della tua.
Non conservare medicinali scaduti o indesiderati. Portali alla tua farmacia locale che li smaltirà per te.
Se hai domande su questo medicinale, chiedi al tuo farmacista.
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Domande frequenti
Can I use aciclovir cream for cold sores inside my mouth or near my eyes?
No, aciclovir cream is not meant for use inside your mouth or vagina, or near your eyes, as it might cause irritation. If you have sores in these areas, it's best to consult your doctor for alternative treatment options.
How can I avoid spreading the herpes virus when I have a cold sore or genital herpes?
If you have a cold sore, avoid kissing and close skin contact with others, especially newborn babies and people with weakened immune systems. For genital herpes, refrain from sexual activity from the moment symptoms appear until they are completely gone, as the virus is highly contagious during this period. Always wash your hands before and after applying the cream to prevent spreading the infection.
What should I do if my immune system is compromised and I have a herpes infection?
If your immune system isn't functioning optimally, for example if you have HIV or AIDS, it's important to inform your doctor. You might require additional antiviral treatment beyond just the cream.
What are the common side effects of aciclovir cream?
Some common side effects include flaking, itchy, or dry skin, and a burning or stinging sensation when the cream is applied. These effects usually don't last long, but if they become bothersome, you should speak with your doctor or pharmacist.
Does aciclovir cream kill the herpes virus?
No, aciclovir cream doesn't kill the herpes simplex virus. Instead, it works by stopping the virus from multiplying. This can help reduce the severity and duration of symptoms, especially if applied early, but it may not have much effect on existing blisters.
Ulteriori letture e riferimenti
- Manufacturer's PIL, Zovirax® Cream; GlaxoSmithKline UK, Il compendio elettronico dei medicinali. Datato novembre 2020.
- Medicinali Completi BNF 89ª Edizione; Associazione Medica Britannica e Società Farmaceutica Reale di Gran Bretagna, Londra.
Informazioni sull'autoreVisualizza il profilo completo

Michael Stewart, MRPharmS
Responsabile Revisione Foglietti Illustrativi – Contrattista, Farmacista
BPharm (Hons), MRPharmS
Michael è un farmacista comunitario che esercita nelle Midlands e nel South Yorkshire con oltre 20 anni di esperienza nel consigliare su farmaci e condizioni mediche. Ha una solida esperienza nella formazione sanitaria, avendo prodotto e tenuto corsi di formazione per team di farmacia e personale di strutture di assistenza residenziale, inclusi infermieri. Ha anche contribuito a consigli consultivi farmaceutici per la gestione di condizioni a bassa gravità nella comunità.
Informazioni sul recensore

Sid Dajani
Sultan Dajani si è laureato alla London School of Pharmacy nel 1994 ed è diventato il più giovane membro eletto del consiglio della Royal Pharmaceutical Society dalla sua fondazione nel 1842.
Storia dell'articolo
Le informazioni su questa pagina sono scritte e revisionate da clinici qualificati.
Articolo disponibile anche in Inglese, Tedesco, Spagnolo, Francese, Italiano, Portoghese, Hindi, Ebraico, Arabo, and Svedese.
Next review due: 8 Nov 2027
5 Nov 2024 | Ultima versione

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