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Etinilestradiolo per i sintomi della menopausa o disturbi mestruali

Nota dell'autore clinico Michael Stewart 18/8/2020: Ethinlyestradiol tablets were discontinued in the UK in July 2020. At the time of review there are no branded or generic products in the UK solely containing ethinylestradiol. It is still available in combination products for oral contraception. Ethinylestradiol may still be available in other countries. This medicine leaflet is based on medical information available in the UK at the time of writing and is left here for reference purposes. Please also refer to the manufacturer's information supplied with your medicine.

For information about ethinylestradiol in contraception please see our separate leaflet called Combined hormonal contraceptives.

Ethinylestradiol is taken in cycles. Make sure you know which days of the month to take a tablet, and which are tablet-free days. If you are uncertain, check with your doctor or pharmacist.

Do not rely on the tablets to prevent pregnancy - they are not intended to be used as a contraceptive.

Your doctor will discuss the benefits and risks of the treatment with you before you begin.

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About ethinylestradiol

Tipo di medicinale

An oestrogen (may also be spelled estrogen)

Utilizzato per

Hormone replacement therapy (HRT); menstrual problems

Disponibile come

Tablets (discontinued)

Ethinylestradiol is a man-made form of the naturally occurring female hormone called oestrogen. It is prescribed to treat period (menstrual) problems, and also to help ease i sintomi della menopausa. It is usually prescribed alongside another female hormone called a progestogen.

Ethinylestradiol is used to supplement or replace the body's natural oestrogen. It helps to relieve many of the problems associated with the menopause, such as hot flushes, night sweats and vaginal dryness. It can also help to protect against 'thinning' of the bones (osteoporosis) although other treatments are usually preferred for this.

This leaflet is appropriate if you have been prescribed ethinylestradiol for a menstrual disorder or for hormone replacement therapy (HRT). If you have been prescribed it for any other reason, please ask your doctor for further advice or refer to the manufacturer's printed information leaflet. Ethinylestradiol is also one of the hormones that are used in the contraceptive pill (the pill) - there is more information about this in a separate leaflet called Combined hormonal contraceptives.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking ethinylestradiol it is important that your doctor knows:

  • If you have any unexplained vaginal bleeding, or if you have ever had a problem with your womb such as fibroids, endometriosi, or endometrial hyperplasia (thickening of the lining of your womb).

  • If you have a heart condition or have had a stroke.

  • If you or a close family member have ever had a problem with a blood clot in a vein or artery.

  • If you have had breast cancer or any lumps in your breast, or if a close family member has had breast cancer.

  • If you have any of the following: diabete (diabete mellito), gallstones, migraine, inflammatory bowel disease, systemic lupus erythematosis (SLE), or porphyria.

  • Se hai un problema con il funzionamento del tuo fegato.

  • Se hai mai avuto la depressione.

  • If you have been told you have high levels of prolactin in your blood (hyperprolactinaemia).

  • If you or a close relative have ever had high levels of lipids in blood (hypertriglyceridaemia).

  • If you had any problems with jaundice, severe itchy blistering, or any involuntary muscle movements during a pregnancy.

  • If you could be pregnant or if you are breastfeeding.

  • Se stai assumendo o utilizzando altri medicinali. Questo include qualsiasi medicinale che stai assumendo e che è disponibile per l'acquisto senza prescrizione, così come i medicinali a base di erbe e complementari.

  • Se hai mai avuto una reazione allergica a un medicinale.

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  • Before you start this treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about ethinylestradiol and will provide you with a full list of the side-effects which you may experience from taking the tablets.

  • It is usual to take one dose of ethinylestradiol a day, although your doctor will ask you to take the tablets on certain days of the month only. It is usual to have 7-10 tablet-free days a month. It is important that you take ethinylestradiol exactly as your doctor tells you to. The directions will be printed on the label of the pack of tablets to remind you, but if there is anything you are still unsure about, ask your pharmacist if you need further advice.

  • Try to take the tablets at the same time of day as this will help you to remember to take your doses regularly. The tablets are easily swallowed with a drink of water.

  • Se dimentichi di prendere una dose, assumerla appena te ne ricordi. Se non te ne ricordi fino al giorno successivo, salta la dose dimenticata. Non prendere due dosi contemporaneamente per compensare una dose mancante.

  • Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress. Also, regularly check your breasts for any lumps and remember to attend for any regular breast screening and cervical smear tests.

  • There are some risks which are associated with taking an oestrogen - your doctor will discuss the benefits and risks of the treatment with you before you start. The risks are reduced when small doses are used for short periods of time. If used for a long time the incidence of breast cancer and other adverse effects may increase. Because of this, the decision to continue the treatment needs to be made individually and your progress should be reviewed regularly. If you have any concerns at any time, make an appointment to discuss them with your doctor.

  • Travelling that involves long periods of immobility (more than three hours) can increase the risk of serious side-effects and in rare cases may lead to blood clots. Taking appropriate exercise during the journey and possibly wearing elastic hosiery can reduce this risk. If you would like more advice about this, speak with your doctor or pharmacist.

  • If you are due to have an operation, tell the person carrying out the surgery that you are taking an oestrogen, as you may be advised to stop the treatment for a while if you are likely to be on bed rest.

  • Do not rely on these tablets to prevent pregnancy - they are not intended to be used as a contraceptive. Your doctor will advise you about whether or not you need to use contraception. If at any time you suspect that you may be pregnant, stop taking ethinylestradiol and consult your doctor as soon as possible.

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Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with ethinylestradiol. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Ethinylestradiol side-effects

Cosa posso fare se sperimento questo?

Sensazione di nausea

Eat simple meals (avoid rich or spicy foods).

Mal di testa

Ask your pharmacist to recommend a suitable painkiller. If the headache continues or is unusually severe, speak to your doctor as soon as possible.

Occhi secchi

If you wear contact lenses, ask your optician for advice if this becomes troublesome.

Stomach cramps, bloating, weight changes, breast tenderness, fluid retention, rash, changes in sexual desire, mood changes, leg cramps, high blood pressure, kidney stones, menstrual bleeding or spotting

Speak with your doctor if any of these become troublesome.

Stop taking the tablets and contact your doctor for advice immediatamente if you develop any of the following symptoms:

  • Sudden chest pain.

  • Sudden breathlessness (or if you cough up blood).

  • Swelling or pain in a leg.

  • An unusually severe headache.

  • Ittero.

Se si verificano altri sintomi che ritieni possano essere dovuti a questo medicinale, discutine con il tuo medico o farmacista.

  • Tenere tutti i medicinali fuori dalla portata e dalla vista dei bambini.

  • Conservare in un luogo fresco e asciutto, lontano da fonti di calore e luce diretta.

Informazioni importanti su tutti i medicinali

Non assumere mai più della dose prescritta. Se sospetti che tu o qualcun altro possa aver assunto un sovradosaggio di questo medicinale, recati al pronto soccorso del tuo ospedale locale. Porta con te il contenitore, anche se è vuoto.

Questo medicinale è per te. Non darlo mai ad altre persone, anche se la loro condizione sembra essere la stessa della tua.

Se acquisti dei medicinali, verifica con un farmacista che siano adatti da assumere insieme agli altri tuoi medicinali.

Se devi sottoporti a un'operazione o a un trattamento dentale, informa la persona che esegue il trattamento sui medicinali che stai assumendo.

Non conservare medicinali scaduti o indesiderati. Portali alla tua farmacia locale che li smaltirà per te.

Se hai domande su questo medicinale, chiedi al tuo farmacista.

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Se si verificano effetti collaterali, è possibile segnalarli online tramite il Yellow Card website.

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Ulteriori letture e riferimenti

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Storia dell'articolo

Le informazioni su questa pagina sono scritte e revisionate da clinici qualificati.

  • Prossima revisione prevista: 13 Ago 2026
  • 14 Ago 2023 | Ultima versione

    Ultimo aggiornamento di

    Michael Stewart, MRPharmS

    Revisione paritaria di

    Sid Dajani
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