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Can I take Ramipril and Ibuprofen together?

Guida alle interazioni farmacologiche

Taking ibuprofen while on ramipril can make your blood pressure medication less effective. More importantly, it can significantly increase the risk of kidney problems and may cause your body to hold onto too much potassium.

You should avoid taking ramipril e ibuprofene together. Always consult your doctor or pharmacist before combining them.

When taking ramipril you should:

  • Avoid taking ibuprofen.

  • Take paracetamolo if pain relief is needed.

  • If you must take ibuprofen, use the lowest dose for the shortest time possible and speak to your GP.

Come sapere se stai avendo un'interazione farmacologica

You may be experiencing an interaction between ramipril and ibuprofen if you have:

  • Swelling in your ankles, feet, or hands.

  • Unexplained fatigue or weakness.

  • Dizziness or lightheadedness.

  • Reduced urination or dark-coloured pee.

  • Unusual shortness of breath.

These can be signs that your kidneys, blood pressure, or fluid balance are being affected.

If you notice these side effects, you should:

  • Stop taking ibuprofen (unless a doctor has specifically told you it’s safe).

  • Contact your doctor or pharmacist immediately.

  • Monitor your symptoms and seek urgent care if they worsen (e.g., severe swelling, very little urine, or extreme dizziness)

  • Do not adjust your ramipril dose on your own.

These steps help prevent serious kidney or heart problems.

Continua a leggere sotto

Ramipril works by relaxing blood vessels and helping the kidneys filter fluid. Ibuprofen blocks natural chemicals called prostaglandins that help keep the blood vessels in the kidneys open.

When both drugs are taken together, the blood flow to the kidneys can drop too low, potentially leading to kidney strain or failure.

Ibuprofen also causes the body to retain salt and water, which opposes the blood-pressure-lowering effect of ramipril.

Gravidanza

You must not take ramipril if you are pregnant or planning to become pregnant as it can cause serious harm to the developing baby, particularly affecting their kidneys.

Asma

Do not take ibuprofen if you have asthma that is worsened by aspirina or other farmaci antinfiammatori non steroidei (FANS), as it can trigger a life-threatening asthma attack.

Kidney function

Taking these two medicines together significantly increases the risk of sudden kidney failure. This risk is even higher if you are also taking a 'water tablet' (diuretic).

Continua a leggere sotto

Alcol

Drinking alcohol while taking ramipril can increase the blood pressure-lowering effect of the medicine, which may make you feel dizzy, lightheaded, or faint. It is best to keep alcohol intake to a minimum, especially when you first start taking ramipril or if your dose is increased.

Sostituti del sale (ricchi di potassio)

Ramipril can increase the levels of potassium in your blood. Using salt substitutes that contain potassium (such as Lo-Salt) can cause your potassium levels to become too high. This can lead to serious heart problems. Check with your pharmacist before using these products.

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Avvertenza

Queste informazioni sono solo a scopo educativo generale e non devono essere considerate un sostituto del consiglio medico professionale. Consultate sempre il vostro medico di base, farmacista o un altro professionista sanitario qualificato prima di prendere decisioni sui vostri farmaci. Le circostanze individuali possono variare, e solo un professionista sanitario che conosce la vostra storia medica può fornire una guida personalizzata.

Storia dell'articolo

Le informazioni su questa pagina sono scritte e revisionate da clinici qualificati.

  • 25 Gen 2026 | Pubblicato originariamente
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