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Can I take Mounjaro and Insulin together?

Guida alle interazioni farmacologiche

Taking Mounjaro (tirzepatide) and insulin together significantly increases your risk of having a 'hypo' (hypoglycaemia), which is when your blood sugar levels drop too low. Symptoms of a hypo can include feeling shaky, sweaty, dizzy, hungry, or confused. In severe cases, it can be dangerous.

Perché succede

Both Mounjaro and insulin work to lower your blood sugar levels. When used at the same time, their effects are additive, meaning they work together to lower blood sugar much more powerfully than either drug would on its own. Additionally, Mounjaro slows down how quickly your stomach empties, which can change how fast your body absorbs sugar from food, potentially making it harder to time your insulin doses correctly.

You must speak to your doctor before starting Mounjaro if you are already using insulin. Your doctor will likely need to reduce your insulin dose to prevent your blood sugar from dropping too low. You should monitor your blood sugar levels more frequently when starting Mounjaro or changing your dose. Always carry a fast-acting glucose source (like glucose tablets or a sugary drink) to treat a hypo if it occurs.

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Hypoglycaemia (Low Blood Sugar)

Using Mounjaro alongside insulin significantly increases your risk of severe hypos. You must monitor your blood sugar more frequently, and your doctor may need to reduce your insulin dose before you start Mounjaro.

Pancreatite

Stop using this medicine and seek immediate medical help if you experience severe, persistent abdominal pain that may radiate to your back, as this can be a sign of acute pancreatitis.

Severe Gastrointestinal Disease

This medicine slows stomach emptying. It is not recommended if you have severe stomach problems, such as gastroparesis (delayed gastric emptying) or inflammatory bowel disease.

Alcol

Alcohol can cause unpredictable changes in blood sugar levels. It can lead to severe low blood sugar (hypoglycaemia) because it prevents the liver from releasing glucose. This effect can last for several hours after drinking. Additionally, alcohol may worsen the nausea and stomach upset often experienced with Mounjaro.

Large or high-fat meals

Mounjaro slows down how quickly your stomach empties. Eating very large or high-fat meals can lead to significant discomfort, bloating, and nausea because the food stays in the stomach longer. It is often recommended to eat smaller, more frequent meals.

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Avvertenza

Queste informazioni sono solo a scopo educativo generale e non devono essere considerate un sostituto del consiglio medico professionale. Consultate sempre il vostro medico di base, farmacista o un altro professionista sanitario qualificato prima di prendere decisioni sui vostri farmaci. Le circostanze individuali possono variare, e solo un professionista sanitario che conosce la vostra storia medica può fornire una guida personalizzata.

Storia dell'articolo

Le informazioni su questa pagina sono scritte e revisionate da clinici qualificati.

  • 25 Gen 2026 | Pubblicato originariamente
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