Posso prendere insieme i medicinali per la tosse a base di Dextrometorfano e Sertralina?

You should speak to your doctor or pharmacist before taking dextromethorphan cough medicine e sertralina together. Combining them can increase the risk of sindrome serotoninergica.

Perché succede

Sertraline is an SSRI antidepressant that increases serotonin levels. Dextromethorphan cough medicines also slightly increases serotonin. When combined, they can raise serotonin to unsafe levels.

Both medicines can also have a calming effect on the central nervous system, which may lead to increased sleepiness.

You may be experiencing an interaction between dextromethorphan and sertraline if you:

• Feel agitated, restless, or confused.

• Have a rapid heartbeat or high blood pressure.

• Are sweating heavily, are shivering, or have a fever.

• Have muscle twitches, stiffness, or a tremor.

• Feel dizzy or drowsy.

• Have a high temperature (fever).

If you develop any of the above symptoms, you should:

• Stop taking dextromethorphan and seek urgent medical advice.

• Do not take any further doses of dextromethorphan until you have spoken to a healthcare professional.

• Tell the healthcare professional that you are taking sertraline. They may suggest a different type of cough medicine that does not contain dextromethorphan (such as a simple linctus or a medicine containing only guaifenesin).

Disturbi depressivi e d'ansia

Potresti sperimentare un aumento dei pensieri suicidi o dell'impulso di autolesionarti all'inizio del trattamento con sertralina o quando cambi la dose. Questo è più comune nei giovani adulti sotto i 25 anni. Contatta immediatamente il tuo medico o vai in ospedale se noti cambiamenti nel tuo umore o nel tuo comportamento.

Bipolar disorder or history of mania

Sertraline can trigger a manic episode (extreme high mood and overactivity) in people with undiagnosed bipolar disorder.

Disturbi della coagulazione o uso di anticoagulanti

La sertralina può aumentare il rischio di sanguinamento grave, soprattutto se stai assumendo anche aspirina, ibuprofene o farmaci anticoagulanti come il warfarin.

Sindrome serotoninergica

Check with a pharmacist before using cough suppressants with sertraline, as the combination can cause a life-threatening reaction called serotonin syndrome.

Alcol

You should avoid drinking alcohol while taking these medicines. Both sertraline and dextromethorphan can cause drowsiness and dizziness; alcohol will significantly increase these effects, making you feel more sleepy and less alert.

Succo di pompelmo

Avoid consuming large amounts of grapefruit juice. Grapefruit can increase the levels of sertraline in your blood, which may increase the risk of side effects.

Caffeina (Caffè, Tè, Bevande Energetiche)

Sertraline can sometimes cause nervousness or tremors. Consuming high amounts of caffeine may worsen these side effects or increase feelings of anxiety. It is advisable to monitor your caffeine intake.

Taking multiple medicines? Our Controllo Interazioni Farmaci helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Avvertenza

Queste informazioni sono solo a scopo educativo generale e non devono essere considerate un sostituto del consiglio medico professionale. Consultate sempre il vostro medico di base, farmacista o un altro professionista sanitario qualificato prima di prendere decisioni sui vostri farmaci. Le circostanze individuali possono variare, e solo un professionista sanitario che conosce la vostra storia medica può fornire una guida personalizzata.