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Can I take Aspirin and Latanoprost % ophthalmic together?

Drug interaction guide

There is a potential for aspirin to slightly reduce the eye-pressure-lowering effect of latanoprost. Additionally, there is a very small risk of increased inflammation or bleeding within the eye, though this is rare.

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Why this happens

Latanoprost works by mimicking natural substances called prostaglandins to lower eye pressure. Aspirin belongs to a group of medicines (NSAIDs) that block the production of prostaglandins. When taken together, aspirin might interfere with how well latanoprost works. There is also a theoretical risk that aspirin's blood-thinning properties could increase the risk of tiny bleeds in the eye (subconjunctival haemorrhage) when used alongside eye drops.

You can generally use these two medicines together, but you should inform your optician or ophthalmologist. If you notice your eye pressure is not being controlled as well as expected, or if you notice any unusual redness or changes in your vision, speak to your doctor. Do not stop taking aspirin if it has been prescribed for your heart or to prevent a stroke without consulting your GP first.

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Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.

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Article history

The information on this page is written and peer reviewed by qualified clinicians.

  • 14 Mar 2026 | Originally published
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