Can I take Amitriptyline and Shortec together?

Perché succede

Both medicines act on the central nervous system to slow down brain activity. Amitriptyline is a tricyclic antidepressant and Shortec is an opioid painkiller; when used together, their sedative effects add up. Additionally, both drugs have 'anticholinergic' effects, which multiply the risk of side effects like constipation and blurred vision.

You should only take these two medicines together if they have been specifically prescribed by your doctor with the knowledge that you are taking both. If you feel excessively sleepy, have shallow breathing, or feel like you might faint, seek medical help immediately. Avoid driving or operating machinery until you know how this combination affects you. Do not drink alcohol while taking these medicines.

Pensieri suicidi e cambiamenti d'umore

L'amitriptilina può aumentare il rischio di pensieri suicidi o autolesionismo, in particolare all'inizio del trattamento o quando si cambiano le dosi. Cerca immediatamente assistenza medica se il tuo umore cambia o ti senti depresso.

Respiratory Depression Risk

Taking these medicines together significantly increases the risk of dangerous breathing difficulties and extreme sleepiness. Do not take other sedatives or drink alcohol while using this combination.

Opioid Dependence and Addiction

Shortec is an opioid that can cause addiction and withdrawal symptoms. It should only be used for the shortest time possible; long-term use for non-cancer pain is rarely effective and increases the risk of dependency.

Disturbi del ritmo cardiaco

Amitriptyline can affect your heart rhythm. It must be used with caution if you have a history of heart disease or a recent heart attack, as it can increase the risk of serious arrhythmias.

Alcol

You must avoid drinking alcohol while taking these medicines. Both amitriptyline and Shortec cause drowsiness and slow down your breathing. Alcohol significantly increases these effects, which can lead to dangerous levels of sedation, breathing difficulties, and loss of consciousness.

Succo di pompelmo

Avoid drinking grapefruit juice or eating grapefruit. It can increase the amount of Shortec in your bloodstream, making side effects like extreme sleepiness or breathing problems more likely.

Caffeine (Coffee, tea, energy drinks)

Amitriptyline can sometimes cause a fast or irregular heartbeat. High amounts of caffeine can worsen this effect and may also increase feelings of restlessness or anxiety.

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Avvertenza

Queste informazioni sono solo a scopo educativo generale e non devono essere considerate un sostituto del consiglio medico professionale. Consultate sempre il vostro medico di base, farmacista o un altro professionista sanitario qualificato prima di prendere decisioni sui vostri farmaci. Le circostanze individuali possono variare, e solo un professionista sanitario che conosce la vostra storia medica può fornire una guida personalizzata.