keratin 86
Ultimo aggiornamento 18 Ago 2020
Rispetta le linee guida editoriali
- ScaricaScarica
- Condividi
- Language
- Discussione
- Versione audio
- Aggiungi alle fonti preferite su Google
L KRT86 gene provides instructions for making the type II hair keratin K86 protein (K86). This protein belongs to a group of proteins known as keratins, which are tough, fibrous proteins that form the structural framework of cells that make up the hair, skin, and nails. Each keratin protein partners with another keratin protein to form molecules called intermediate filaments. These filaments assemble into strong networks that provide strength and resiliency to the tissues and protect them from being damaged by everyday physical stresses. The K86 protein is found in cells that make up the inner compartment of the hair shaft known as the cortex, and this protein helps give hair its strength and elasticity.
Normal function
L KRT86 gene provides instructions for making the type II hair keratin K86 protein (K86). This protein belongs to a group of proteins known as keratins, which are tough, fibrous proteins that form the structural framework of cells that make up the hair, skin, and nails. Each keratin protein partners with another keratin protein to form molecules called intermediate filaments. These filaments assemble into strong networks that provide strength and resiliency to the tissues and protect them from being damaged by everyday physical stresses. The K86 protein is found in cells that make up the inner compartment of the hair shaft known as the cortex, and this protein helps give hair its strength and elasticity.
Conditions referring to this gene or chromosome
Altri nomi
hair keratin K2.11
hard keratin, type II, 6
HB6
hHb6
K86
keratin 86, type II
keratin K-86
keratin protein HB6
keratin-86
KRT86_HUMAN
KRTHB6
MNX
type II hair keratin Hb6
Related patient information and medicines
Patient information leaflet
Malattia di Bowen
Keratinocytes. Questi cells are in layers above the basal layer. They make a substance called keratin which is a hard waxy material. Cheratinociti are constantly dividing and a certain number are dying at any given time. The top (horny) layer of the epidermis is made of dead keratinocytes which contain keratin. The top of the skin is constantly.
Patient information leaflet
Colesteatoma
Cholesteatoma is the name given to a collection of skin cells that form a pearly-white greasy-looking lump deep in the ear, usually at the top of the area behind the eardrum. What is a cholesteatoma. A cholesteatoma is a non-cancerous abnormal growth of skin-like tissue in the middle ear. Cholesteatomas ... What does a cholesteatoma look like. In.
Patient information leaflet
Tipi di cancro della pelle
This leaflet gives a general overview about skin cancer and the different skin cancer types - melanoma and non-melanoma. What is cancer. These cells are in layers above the basal layer. They make a substance called keratin which is a hard wax-like material. Keratinocytes are constantly dividing and a certain number are dying at any given time. The.
Patient information leaflet
Calli e duroni
Chemical treatment... These usually contain salicylic acid, which is also present in many wart-removal products. Salicylic acid is a keratolytic, which means it dissolves the protein (keratin) that makes up most of entrambi the corn and the thick layer of dead skin which usually tops it. It is important to use these products as directed in the package.
Patient information leaflet
Milia
In other people, they may take longer to clear. In persistent cases, treatment may be suggested. What are milia. A milium is a small, raised bump on the skin. It is a type of tiny skin cyst filled with a protein called keratin. Many are usually found together and so they are called milia (the plural of milium). What do milia look like. As can be.
Patient information leaflet
Cisti epidermoidali e pilari
Epidermoid and pilar cysts are commonly referred to as 'sebaceous cysts' (pronounced 'seb-ay-shuss'). They are overgrowths of skin cells (called keratin) held together in a little capsule, or sac. They are harmless smooth lumps just under the surface o... This substance is soggy keratin. Keratin is made by skin cells and is the substance that.
Ulteriori letture e riferimenti
- keratin 86; MedlinePlus, National Library of Medicine.
- Djabali K, Panteleyev AA, Lalin T, Garzon MC, Longley BJ, Bickers DR, Zlotogorski A, Christiano AM. Recurrent missense mutations in the hair keratin gene hHb6 in monilethrix. Clin Exp Dermatol. 2003 Mar;28(2):206-10. doi: 10.1046/j.1365-2230.2003.01196.x.
- Hofmann I, Winter H, Mucke N, Langowski J, Schweizer J. The in vitro assembly of hair follicle keratins: comparison of cortex and companion layer keratins. Biol Chem. 2002 Sep;383(9):1373-81. doi: 10.1515/BC.2002.156.
- Korge BP, Hamm H, Jury CS, Traupe H, Irvine AD, Healy E, Birch-MacHin M, Rees JL, Messenger AG, Holmes SC, Parry DA, Munro CS. Identification of novel mutations in basic hair keratins hHb1 and hHb6 in monilethrix: implications for protein structure and clinical phenotype. J Invest Dermatol. 1999 Oct;113(4):607-12. doi: 10.1046/j.1523-1747.1999.00722.x.
- Langbein L, Rogers MA, Winter H, Praetzel S, Schweizer J. The catalog of human hair keratins. II. Expression of the six type II members in the hair follicle and the combined catalog of human type I and II keratins. J Biol Chem. 2001 Sep 14;276(37):35123-32. doi: 10.1074/jbc.M103305200. Epub 2001 Jul 9.
- Rogers MA, Langbein L, Praetzel S, Moll I, Krieg T, Winter H, Schweizer J. Sequences and differential expression of three novel human type-II hair keratins. Differentiation. 1997 Feb;61(3):187-94. doi: 10.1046/j.1432-0436.1997.6130187.x.
- Schweizer J, Bowden PE, Coulombe PA, Langbein L, Lane EB, Magin TM, Maltais L, Omary MB, Parry DA, Rogers MA, Wright MW. New consensus nomenclature for mammalian keratins. J Cell Biol. 2006 Jul 17;174(2):169-74. doi: 10.1083/jcb.200603161. Epub 2006 Jul 10.
- Winter H, Rogers MA, Langbein L, Stevens HP, Leigh IM, Labreze C, Roul S, Taieb A, Krieg T, Schweizer J. Mutations in the hair cortex keratin hHb6 cause the inherited hair disease monilethrix. Nat Genet. 1997 Aug;16(4):372-4. doi: 10.1038/ng0897-372.
Partecipa alla conversazione
Condividi i tuoi pensieri o esperienze con gli altri nel nostro comunità di pazienti.
Chiedi, condividi, connettiti.
Esplora le discussioni, fai domande e condividi esperienze su centinaia di argomenti di salute.
Iscriviti alla newsletter di Patient
La tua dose settimanale di consigli sulla salute chiari e affidabili - scritti per aiutarti a sentirti informato, sicuro e in controllo.
Abbonandoti accetti i nostri Informativa sulla Privacy. Puoi annullare l'iscrizione in qualsiasi momento. Non vendiamo mai i tuoi dati.