Norethisterone contraceptive injection
Noristerat
Revisione paritaria di Sid DajaniUltimo aggiornamento di Michael Stewart, MRPharmSUltimo aggiornamento 27 Gen 2023
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Norethisterone injection is given to prevent pregnancy. It provides contraception for about eight weeks.
Read the manufacturer's information leaflet from the pack before having the injection.
The most common side-effect is irregular menstrual bleeding.
A colpo d'occhio
Norethisterone injection is a short-term contraceptive, providing protection for about eight weeks.
It works by preventing ovulation, changing the womb lining, and thickening cervical mucus.
You will receive an injection into your buttock muscle, usually during the first 1-5 days of a period.
Your periods may change, with possible spotting, breakthrough bleeding, or irregular bleeding.
Some medicines can reduce its effectiveness, so inform your doctor about all medications you are taking.
Common side-effects include spotting, irregular periods, headache, and feeling sick.
The injection does not protect against HIV or other sexually transmitted infections.
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About norethisterone contraceptive injection
Tipo di medicinale | Progestogen |
Utilizzato per | Contraccezione |
Chiamato anche | Norethindrone (in US); Noristerat® |
Disponibile come | Iniezione |
Norethisterone is a progestogen, which is a female sex hormone similar to the progesterone hormone made naturally by your ovaries. It is an effective and convenient form of short-term contraccezione. The injection will provide contraception for about eight weeks.
Norethisterone works mainly by stopping ovulation (the release of an egg from the ovary). It also changes the lining of your womb (uterus) to make it less likely that an egg would attach to it, even if an egg were to fertilise. In addition, the mucus which forms a plug in the neck of your womb (cervix) becomes thicker. This stops sperm getting through to the womb to fertilise an egg.
Before you have norethisterone contraceptive injection
Torna ai contenutiSome medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before having Noristerat® it is important that your doctor knows:
If you think you could already be pregnant.
Se hai problemi con il funzionamento del tuo fegato.
Se hai un problema con le tue arterie, chiamato malattia arteriosa.
Se hai una cisti ovarica o qualsiasi sanguinamento vaginale diverso dal tuo normale ciclo mensile.
If you have systemic lupus erythematosus (this is an inflammatory condition, often called SLE).
If you have ever had an ectopic pregnancy or if you have developed severe itching of your skin, or yellowing of your skin or the whites of your eyes (jaundice) during a pregnancy.
Se hai avuto un tumore al seno o un tumore che ti è stato detto dipende da un ormone sessuale.
Se hai mai avuto la depressione.
Se hai un raro disturbo ereditario del sangue chiamato porfiria.
Se hai mai avuto una reazione allergica a un medicinale.
If you are taking any other medicines, including those available to buy without a prescription, as well as herbal and complementary medicines. This is because some medicines interfere with the way progestogen contraceptives work.
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How norethisterone contraceptive injection is given
Torna ai contenutiBefore you are given the injection you will be asked to read a printed information leaflet from the manufacturer. The manufacturer's leaflet will give you important information about the injection and will provide a full list of the side-effects which you may experience from it. If you have any questions as a result of reading the leaflet, please discuss them with your doctor/nurse before you have the injection. You will be given the leaflet to take home.
You will be given the injection by your nurse or doctor. It is usually given during the first 1-5 days of a period. The norethisterone is injected slowly into a muscle in your buttock. From there, it is gradually released into your bloodstream.
Ottenere il massimo dal tuo trattamento
Torna ai contenutiYour periods are likely to change. Spotting, breakthrough bleeding and delayed periods may occur. Some women have irregular bleeding which can be heavier and longer than normal. Irregular bleeding can sometimes also be due to another reason (such as an infection), so let your doctor know if it happens.
Norethisterone injection provides contraception for eight weeks. It is often given as an interim measure - for example, while your partner is having a vasectomy. Make sure your doctor knows if there is any delay to your longer-term plans for contraception.
You may gain a little weight. Eating a well-balanced diet and taking regular exercise can help to keep this to a minimum.
Regularly check your breasts for any lumps or bumps. Speak with your doctor if you notice any changes.
Please note: the injection will not protect you against HIV (AIDS) or any other sexually transmitted infections.
Some medicines can reduce the effectiveness of this contraceptive. These include medicines for epilepsy, medicines to treat fungal infections, the herbal preparation St John's wort, and medicines used to treat tuberculosis (TB). Tell the doctor that you have had a progestogen contraceptive injection if you are prescribed any other medicines. If you buy any medicines 'over the counter', ask the pharmacist for advice.
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Can norethisterone contraceptive injection cause problems?
Torna ai contenutiAlong with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with a norethisterone contraceptive injection. You will find a full list in the manufacturer's information leaflet that has been given to you. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Very common Noristerat® side-effects (questi colpiscono più di 1 donna su 10) | Cosa posso fare se sperimento questo? |
Spotting | Se sei preoccupato, parla con il tuo medico |
Cicli irregolari | Fate sapere al vostro medico se ciò accade |
Common Noristerat® side-effects (these affect fewer than 1 in 10 women) | Cosa posso fare se sperimento questo? |
Mal di testa | Chiedi al tuo farmacista di consigliare un antidolorifico adatto |
Sensazione di nausea | This does not usually last for long but in the meantime, stick to simple meals |
Increased weight, skin reactions, feeling dizzy | Se problematico, parla con il tuo medico |
If you experience any other symptoms which you think may be due to the injection, speak with your doctor or pharmacist for advice.
Informazioni importanti su tutti i medicinali
Torna ai contenutiInformazioni importanti su tutti i medicinali
Se devi sottoporti a un'operazione o a un trattamento dentale, informa la persona che esegue il trattamento su quali medicinali stai assumendo o utilizzando.
Non conservare mai medicinali scaduti o indesiderati. Portali alla tua farmacia locale che li smaltirà per te.
If you have any questions about your medicines, ask your pharmacist.
Segnala effetti collaterali di un medicinale o vaccino
Se si verificano effetti collaterali, è possibile segnalarli online tramite il Sito web Yellow Card.

Non sei sicuro di mescolare i medicinali?
Controlla le possibili interazioni tra farmaci, integratori e alimenti prima di assumerli insieme.
Domande frequenti
How long does the norethisterone injection provide contraception for?
The norethisterone contraceptive injection provides protection against pregnancy for approximately eight weeks.
What should I do if I am already taking other medications?
Before you receive the norethisterone injection, inform your doctor about all other medicines you are taking. This includes prescription, over-the-counter, herbal, and complementary medicines, as some can interfere with how progestogen contraceptives work.
Can I use norethisterone if I plan to have a longer-term contraceptive method later?
Yes, norethisterone injection is often used as a temporary measure, for example, if you are waiting for a partner to have a vasectomy, or while you are making arrangements for a different long-term contraceptive method. Make sure your doctor is aware of any delays to your longer-term plans.
Does norethisterone protect against sexually transmitted infections?
No, the norethisterone injection will not protect you against HIV (AIDS) or any other sexually transmitted infections.
What should I do if I experience changes in my periods after the injection?
It is common for your periods to change, including spotting, breakthrough bleeding, or delayed periods. Some women may experience irregular bleeding that is heavier and longer than usual. While these changes are expected, you should let your doctor know if you experience irregular bleeding, as it could sometimes be due to another reason like an infection.
What should I do if the side effects become troublesome or continue?
Many unwanted effects improve as your body adjusts to the medicine. However, if any side effects continue or become troublesome, or if you experience any other symptoms you think might be due to the injection, you should speak with your doctor or pharmacist for advice.
Ulteriori letture e riferimenti
- Manufacturer's PIL, Noristerat® 200 mg solution for intramuscular injection; Bayer plc, The electronic Medicines Compendium. Dated June 2019.
- Medicinali Completi BNF 89ª Edizione; Associazione Medica Britannica e Società Farmaceutica Reale di Gran Bretagna, Londra.
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Informazioni sull'autoreVisualizza il profilo completo

Helen Allen, MPharm
Pharmacist, Medical Author
MPharm
Helen Allen qualified as a Pharmacist in 1979 and spent 3 years as the drug information leaflets' author for EMIS.
Informazioni sul recensore

Sid Dajani
Sultan Dajani si è laureato alla London School of Pharmacy nel 1994 ed è diventato il più giovane membro eletto del consiglio della Royal Pharmaceutical Society dalla sua fondazione nel 1842.
Storia dell'articolo
Le informazioni su questa pagina sono scritte e revisionate da clinici qualificati.
Prossima revisione prevista: 26 Lug 2027
27 Gen 2023 | Ultima versione
20 Aprile 2011 | Pubblicato originariamente
Autore:
Helen Allen, MPharm

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