Capsule di Idarubicina
Zavedos
Revisione paritaria di Sid DajaniUltimo aggiornamento di Michael Stewart, MRPharmSUltimo aggiornamento 19 giu 2023
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Swallow idarubicin capsules whole with a drink of water - do not bite, chew or suck the capsules.
Idarubicin may colour your urine red. This is nothing to worry about and will disappear after a day or two.
Keep your regular appointments with your doctor or hospital. You will need to have frequent blood tests and check-ups.
The most common side-effects are diarrhoea, feeling sick (nausea), sore mouth, and an increased risk of infection.
A colpo d'occhio
Idarubicin is a chemotherapy medicine used to treat leukaemia and breast cancer.
It stops cancer cells from growing and dividing in the body.
You can take it as capsules or it can be given as an injection.
Do not get pregnant or father a child while taking idarubicin.
It can increase your risk of infection, so avoid people with infections.
Seek medical advice if you are sick after taking a dose or forget a dose.
Contact your doctor if you develop a high temperature or any signs of infection.
About idarubicin
Tipo di medicinale | An anthracycline chemotherapy medicine |
Utilizzato per | Treatment of leukaemia and breast cancer |
Chiamato anche | Zavedos® |
Disponibile come | Capsules and injection |
Idarubicin is used to treat some cancers. It is given in particular to treat leucemia, which is cancer of white blood cells. It is also given for cancro al seno if other treatments have not proved effective. It can be used alone or alongside other medicines for the treatment of cancer.
In cancer, certain cells in the body grow and multiply too fast. Chemotherapy (anti-cancer) medicines like idarubicin work by preventing the growth and division of cells, and this reduces the number of cancer cells your body makes. Idarubicin is usually given as an injection but it can also be taken by mouth in the form of capsules. This leaflet provides information about idarubicin capsules.
Before taking idarubicin
Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking idarubicin it is important that your doctor or pharmacist knows:
Se sei incinta o stai allattando.
Se hai problemi con il funzionamento del tuo fegato o con il funzionamento dei tuoi reni.
Se hai un'infezione o ti senti male.
If you have a heart condition, such as if you have had a heart attack in the past or if you have an unusual heartbeat.
Se stai assumendo o utilizzando altri medicinali. Questo include qualsiasi medicinale che stai assumendo e che è disponibile per l'acquisto senza prescrizione, così come i medicinali a base di erbe e complementari.
Se hai mai avuto una reazione allergica a un medicinale.
How to take idarubicin
Before you start this treatment, read any printed information you have been given by your doctor and the printed manufacturer's leaflet from inside your pack of capsules. These will give you more information about idarubicin and will provide a full list of side-effects which you may experience from taking it.
Idarubicin will be given to you by a specialist doctor who is experienced in treating your condition. Your doctor will calculate what dose is right for you and will tell you how many capsules to take each day - it is important that you take idarubicin exactly as you are told to. Your dose will also be printed on the label of your pack. If you are unsure about what to do, or if you have any other concerns, you should contact your doctor or hospital clinic for advice.
Swallow the capsules whole with a drink of water. Do not open or chew the capsules. Try to take idarubicin at the same time each day, as this will help you to remember to take your doses. You can take the capsules before food, or after a light meal if preferred.
Your doctor will tell you how long your course of treatment will last. For some people this can just be a single dose; for others it can be a three-day course of treatment. You may or may not be asked to repeat the course of treatment after a few weeks.
If you are sick shortly after taking a dose, or if you forget a dose, contact your doctor or clinic for advice on what to do. You will be told whether to take the dose again, or wait until the next dose is due.
Ottenere il massimo dal tuo trattamento
You must try to keep your regular appointments with your doctor or hospital. This is so your doctor can check on your progress. You will need to have regular blood tests and check-ups during treatment.
Idarubicin lowers the number of white cells in your blood, increasing the chance of you getting an infection. You should take certain precautions to reduce the risk of infection - if possible, avoid people with infections and let your doctor know if you think you are getting a sore throat or if you have a high temperature.
Idarubicin may colour your urine red. There is no need to be concerned about this as it will go after a day or so. A few people taking idarubicin have noticed that their skin and nails have become discoloured too, although this occurs less often than the colour change to urine.
It is important that you do not get pregnant or father a child while you are taking idarubicin. Make sure you have discussed with your doctor which types of contraception are suitable for you and your partner. To prevent pregnancy, women should use effective contraception for at least six months after finishing treatment. Men should continue to use contraception for three months after finishing treatment.
While you are taking idarubicin and for a while after you stop treatment, do not have any immunisations (vaccinations) without talking to your doctor first. Idarubicin lowers your body's resistance so there is a chance that you may get an infection from some vaccines.
Se devi sottoporti a un'operazione o a un trattamento dentistico, informa la persona che esegue il trattamento sui medicinali che stai assumendo.
Can idarubicin cause problems?
Along with their useful effects, most medicines can cause side-effects although not everyone experiences them. Before you start treatment with idarubicin, your doctor will discuss with you the possibility of unwanted side-effects occurring. The table below contains some of the most common ones. You will find a full list of side-effects in the manufacturer's information leaflet supplied with your capsules.
Very common idarubicin side-effects (these affect more than 1 in 10 people) | Cosa posso fare se sperimento questo? |
Diarrea | Bevi molta acqua per reintegrare i liquidi persi. Se questo continua, parla con il tuo medico |
Sensazione di malessere (nausea) o vomito | Attieniti a cibi semplici. Informa il tuo medico di questo, poiché un medicinale contro la nausea potrebbe aiutare |
Sore mouth or mouth ulcers | Lavarsi i denti 2-3 volte al giorno con uno spazzolino morbido e utilizzare regolarmente un collutorio può aiutare a prevenire questo. Se le ulcere della bocca diventano un problema, parla con il tuo medico |
A high temperature (fever), or symptoms of an infection | Informi subito il suo medico di questo |
Headache, tummy (abdominal) pain, chills, hair loss, lack of appetite, rash | Speak with your doctor or clinic for advice |
Other common side-effects include anaemia, bleeding, heart problems, and reduced numbers of blood cells | Il tuo medico controllerà questi |
If you experience any other symptoms which you think may be due to the capsules, speak with your doctor or pharmacist.
How to store idarubicin
Tenere tutti i medicinali fuori dalla portata e dalla vista dei bambini.
Conservare in un luogo fresco e asciutto, lontano da fonti di calore e luce diretta.
Return any unused or unwanted capsules to your clinic or pharmacy to destroy. They will need special disposal.
Informazioni importanti su tutti i medicinali
Informazioni importanti su tutti i medicinali
Non assumere mai più della dose prescritta. Se sospetti che tu o qualcun altro possa aver assunto un sovradosaggio di questo medicinale, recati al pronto soccorso del tuo ospedale locale. Porta con te il contenitore, anche se è vuoto.
Questo medicinale è per te. Non darlo mai ad altre persone, anche se la loro condizione sembra essere la stessa della tua.
Non conservare medicinali scaduti o indesiderati. Portali alla tua farmacia locale che li smaltirà per te.
Se hai domande su questo medicinale, chiedi al tuo farmacista.
Segnala effetti collaterali di un medicinale o vaccino
Se si verificano effetti collaterali, è possibile segnalarli online tramite il Sito web Yellow Card.

Non sei sicuro di mescolare i medicinali?
Controlla le possibili interazioni tra farmaci, integratori e alimenti prima di assumerli insieme.
Domande frequenti
If idarubicin can be given by injection or capsule, why does this leaflet only provide information about the capsules?
This particular leaflet focuses specifically on idarubicin capsules. While the medicine can be administered through injection, the information provided here is tailored to the oral capsule form of the treatment.
What is the typical duration for idarubicin treatment?
The duration of your idarubicin treatment will be determined by your doctor. For some individuals, it might be a single dose, while for others, it could be a three-day course. Your doctor may also decide if the treatment needs to be repeated after a few weeks.
What precautions should I take if idarubicin makes me more susceptible to infections?
Since idarubicin lowers your white blood cell count, increasing your risk of infection, you should try to avoid contact with people who have infections. It's also important to inform your doctor immediately if you notice symptoms like a sore throat or a high temperature.
How often will I need blood tests while on idarubicin?
You will need to have regular blood tests and check-ups during your treatment with idarubicin. This allows your doctor to monitor your progress and ensure the treatment is working effectively.
Why can't I have immunisations (vaccinations) while taking idarubicin?
You should not have immunisations (vaccinations) while taking idarubicin and for a period after treatment without first consulting your doctor. Idarubicin reduces your body's natural resistance, which means there's a risk you could develop an infection from some vaccines.
Ulteriori letture e riferimenti
- Manufacturer's PIL, Zavedos® Capsules 5 mg and 10 mg; Pfizer Limited, The electronic Medicines Compendium. Dated November 2021.
Informazioni sull'autoreVisualizza il profilo completo

Michael Stewart, MRPharmS
Responsabile Revisione Foglietti Illustrativi – Contrattista, Farmacista
BPharm (Hons), MRPharmS
Michael è un farmacista comunitario che esercita nelle Midlands e nel South Yorkshire con oltre 20 anni di esperienza nel consigliare su farmaci e condizioni mediche. Ha una solida esperienza nella formazione sanitaria, avendo prodotto e tenuto corsi di formazione per team di farmacia e personale di strutture di assistenza residenziale, inclusi infermieri. Ha anche contribuito a consigli consultivi farmaceutici per la gestione di condizioni a bassa gravità nella comunità.
Informazioni sul recensore

Sid Dajani
Sultan Dajani si è laureato alla London School of Pharmacy nel 1994 ed è diventato il più giovane membro eletto del consiglio della Royal Pharmaceutical Society dalla sua fondazione nel 1842.
Storia dell'articolo
Le informazioni su questa pagina sono scritte e revisionate da clinici qualificati.
Articolo disponibile anche in Inglese, Tedesco, Spagnolo, Francese, Italiano, Portoghese, Hindi, Ebraico, Arabo, and Svedese.
Prossima revisione prevista: 18 Dic 2027
19 giu 2023 | Ultima versione

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