Can I take Fluoxetine and Venlafaxine together?

You should not take fluoxetina e venlafaxine together unless specifically instructed and closely monitored by a specialist.

Both fluoxetine and venlafaxine work by increasing serotonin levels in the brain. When used together, their effects add up (an additive effect).

Additionally, fluoxetine can slow down the way your liver breaks down venlafaxine, causing the levels of venlafaxine in your blood to rise even higher.

Come sapere se stai avendo un'interazione farmacologica

You may be experiencing a drug interaction between fluoxetine and venlafaxine if you notice:

• Agitation, restlessness or confusion.

• Shivering, sweating or fever.

• Muscle twitching or stiffness.

• Fast heartbeat.

• Diarrea.

• Mal di testa.

• Feeling unusually anxious or overactive.

These can be signs of sindrome serotoninergica, a rare but serious reaction.

Seek urgent medical help if you have:

• High fever.

• Severe agitation or confusion.

• Convulsioni.

• Irregular heartbeat.

• Loss of consciousness.

If you are experiencing any of the above symptoms you should:

• Seek emergency medical help (call 999 / go to A&E) if symptoms are severe, worsening quickly, or include high fever, confusion, seizures, or loss of consciousness.

• Do not take any further doses until you have spoken to a healthcare professional.

• Do not stop either medicine suddenly unless a doctor tells you to, as this can cause withdrawal symptoms.

If your doctor is switching you from one to the other, they will usually advise a 'washout' period (a gap of a few weeks) because fluoxetine stays in your system for a long time.

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Avvertenza

Queste informazioni sono solo a scopo educativo generale e non devono essere considerate un sostituto del consiglio medico professionale. Consultate sempre il vostro medico di base, farmacista o un altro professionista sanitario qualificato prima di prendere decisioni sui vostri farmaci. Le circostanze individuali possono variare, e solo un professionista sanitario che conosce la vostra storia medica può fornire una guida personalizzata.