Can I take Chaga and Turkey tail together?
Drug interaction guide
Originally published 25 Jan 2026
Meets Patient’s editorial guidelines
- DownloadDownload
- Share
- Language
- Discussion
- Audio Version
- Add to preferred sources on Google
Taking chaga and turkey tail together may increase the risk of bleeding and could potentially lower your blood sugar levels more than expected. Both are medicinal mushrooms that have similar effects on the body.
Why this happens
Both chaga and turkey tail have 'antiplatelet' effects, meaning they make the blood less sticky and slower to clot. They also both possess hypoglycaemic properties, which means they can lower blood glucose levels. Taking them together creates an additive effect where these actions are strengthened.
What you should do
It is generally safe for most healthy people to take these together, but you should use caution. If you are scheduled for surgery, stop taking both at least two weeks beforehand. If you have diabetes or take blood-thinning medication (like warfarin or aspirin), you must speak to your doctor before combining these supplements. Monitor yourself for signs of easy bruising or unusual bleeding.
Important precautions
Kidney disease or history of kidney stones
Chaga is extremely high in oxalates, which can cause permanent kidney damage or acute kidney failure, especially in those with existing renal issues.
Diabetes
These mushrooms may significantly lower blood sugar levels, increasing the risk of hypoglycaemia (dangerously low blood sugar) if you are taking insulin or other diabetes medications.
Autoimmune diseases (e.g., Lupus, MS, Rheumatoid Arthritis)
These mushrooms can stimulate the immune system, which may worsen symptoms of autoimmune conditions or interfere with immunosuppressant medications.
Bleeding disorders or upcoming surgery
These mushrooms may slow blood clotting and increase the risk of bleeding; it should be avoided if you have a bleeding disorder or are scheduled for surgery.
Food and drink warnings
Alcohol
Chaga contains high levels of oxalates. Combining it with alcohol may increase the risk of kidney stones or kidney stress, as both substances can affect renal function. Use with caution.
Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
Patient picks for Drug interactions

Drug interactions checker
Can I take Mounjaro and Paracetamol together?
Mounjaro may slow down how quickly your body absorbs paracetamol. This means it might take longer for the paracetamol to start working to relieve pain or reduce a fever. However, the total amount of medicine that gets into your system should remain the same.

Drug interactions checker
Can I take Allopurinol and Nortriptyline together?
There is no known direct interaction between allopurinol and nortriptyline. However, both medications can occasionally cause side effects that affect the liver or blood counts. Taking them together does not typically increase these risks, but it is important to be aware of how you feel.
Article history
The information on this page is written and peer reviewed by qualified clinicians.
Article also available in English, German, Spanish, French, Italian, Portuguese, Hindi, Hebrew, Arabic, and Swedish.
25 Jan 2026 | Originally published
Join the conversation
Share your thoughts or experiences with others in our patient communities.

Ask, share, connect.
Browse discussions, ask questions, and share experiences across hundreds of health topics.

Feeling unwell?
Assess your symptoms online for free
Sign up to the Patient newsletter
Your weekly dose of clear, trustworthy health advice - written to help you feel informed, confident and in control.
By subscribing you accept our Privacy Policy. You can unsubscribe at any time. We never sell your data.
More in drug interactions checker
- Can I take Amitriptyline and Quinine together?
- Can I take Amitriptyline and Sertraline together?
- Can I take Ashwagandha and Sertraline together?
- Can I take Atorvastatin and Cordyceps together?
- Can I take Atorvastatin and Rybelsus (semaglutide) together?
- Can I take Bisoprolol and Fibre supplements together?
- Can I take Certican (Everolimus) and Matcha together?
- Can I take Chaga and Shiitake together?
- Can I take Clopidogrel and Paracetamol together?
- Can I take Fexofenadine and Losartan together?
- Can I take Fexofenadine and Tizanidine together?
- Can I take Flecainide and Mirabegron together?
- Can I take Fluanxol and Sedoxil together?
- Can I take Folic acid and Vitamin C together?
- Can I take Iron and Levothyroxine together?
- Can I take Levothyroxine and Liothyronine together?
- Can I take Pregabalin and Tramadol together?
- Can I take Promethazine and Vitamin D3 together?
- Can I take St John's wort and Vitamin B2 together?
- Can I take Stexerol D3 and Sukkarto together?