Can I take Biotin and Collagen together?
Drug interaction guide
Originally published 25 Jan 2026
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There are no known harmful interactions between biotin and collagen. In fact, they are frequently taken together in 'hair, skin, and nails' supplements because they work in different ways to support the body's connective tissues.
Why this happens
Biotin is a B-vitamin (B7) that helps the body convert nutrients into energy and supports the production of keratin. Collagen is a structural protein that provides the 'building blocks' for skin and joints. They do not interfere with each other's absorption, metabolism, or excretion.
What you should do
It is safe to take these together. However, be aware that high doses of biotin can interfere with certain medical blood tests (such as thyroid or heart enzyme tests). If you are due to have a blood test, tell your doctor or the lab staff that you are taking a biotin supplement.
Important precautions
Blood test interference
Biotin can significantly interfere with laboratory blood tests, including thyroid function and heart attack markers (troponin), leading to dangerously incorrect results. You must stop taking biotin at least 48 to 72 hours before any blood tests and inform your doctor you have been taking it.
Food and drink warnings
Raw egg whites
Consuming large amounts of raw egg whites over a long period can prevent your body from absorbing biotin. This is because raw egg whites contain a protein called avidin that binds to biotin. Cooked eggs do not cause this issue.
Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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