Posso prendere Atorvastatina e Omeprazolo insieme?

It is generally considered safe to take atorvastatina e omeprazolo together, but with caution, as omeprazole may increase blood levels of atorvastatin.

It is often helpful to take your atorvastatin at the same time each day to maintain steady levels in your body.

Perché succede

Omeprazole can affect the way the body breaks down atorvastatin by interfering with certain enzymes in the liver (CYP3A4) and transport proteins. It also changes the acidity of the stomach, which can slightly alter how much of the statin is absorbed into the bloodstream.

You may be experiencing an interaction between atorvastatin and omeprazole if:

• You develop new or worsening muscle pain, tenderness, or weakness.

• You feel unusually tired or weak without a clear reason.

• You notice dark-coloured pee (urine).

• You experience unexplained muscle cramps.

• Blood tests show raised muscle enzymes (CK levels) or changes in liver function.

• Symptoms start soon after starting or changing the dose of either medicine.

Serious interactions are uncommon, but always speak to a doctor or pharmacist if you notice new or worrying symptoms while taking both medicines.

Se hai uno dei sintomi sopra elencati, dovresti:

• Contatta il tuo medico di base o il farmacista per un consiglio il prima possibile.

• Do not stop taking your medicines suddenly unless advised by a healthcare professional

• Seek urgent medical help if muscle pain is severe, widespread, or worsening

• Get medical advice immediately if you notice dark urine or severe weakness

• Tell your healthcare professional about all medicines and supplements you are taking

• Attend any blood tests arranged to check muscle or liver health

Gravidanza

Non devi assumere atorvastatina se sei incinta o stai pianificando di diventarlo, poiché può danneggiare il bambino in via di sviluppo. Usa un contraccettivo efficace mentre lo assumi.

Dolore o debolezza muscolare - atorvastatina

Report any unexplained muscle pain, tenderness, or weakness to your doctor immediately. In rare cases, this can lead to serious kidney problems.

Severe or persistent diarrhoea

Contact your doctor if you develop severe or watery diarrhoea that does not stop, as omeprazole can increase the risk of a serious bowel infection called C. difficile.

Succo di pompelmo

Il succo di pompelmo può aumentare il livello di atorvastatina nel sangue, il che può aumentare il rischio di effetti collaterali come il dolore muscolare. Evitare di bere grandi quantità (più di 1,2 litri al giorno), anche se un piccolo bicchiere di solito va bene.

Alcol

Drinking large amounts of alcohol while taking atorvastatin can increase the risk of liver problems. It is best to keep your intake within the recommended limits.

Taking multiple medicines? Our Controllo Interazioni Farmaci helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Avvertenza

Queste informazioni sono solo a scopo educativo generale e non devono essere considerate un sostituto del consiglio medico professionale. Consultate sempre il vostro medico di base, farmacista o un altro professionista sanitario qualificato prima di prendere decisioni sui vostri farmaci. Le circostanze individuali possono variare, e solo un professionista sanitario che conosce la vostra storia medica può fornire una guida personalizzata.