Can I take Apixaban and Sertraline together?

Perché succede

Apixaban is an anticoagulant (blood thinner) that prevents clots. Sertraline is an SSRI antidepressant which, as a side effect, can reduce the ability of your platelets to stick together. When both medicines work to 'thin' the blood in different ways, the risk of bleeding rises.

You can take these together if your doctor has prescribed both, but you must be extra vigilant. Watch for signs of unusual bleeding, such as blood in your urine, black tarry stools, coughing up blood, or heavy nosebleeds. Seek medical advice immediately if you have a fall or a head injury.

Increased bleeding risk

Taking these medicines together significantly increases your risk of serious internal bleeding. You must watch for signs like coughing up blood, vomit that looks like coffee grounds, or black, tarry stools.

Emergency surgery or injury

Because apixaban prevents blood clotting, you are at risk of life-threatening bleeding if you have a serious injury or need emergency surgery. You must carry an anticoagulant alert card at all times to inform medical staff.

Low blood sodium (Hyponatraemia)

This medicine can cause a dangerous drop in sodium levels, especially in the elderly. Seek medical help if you experience new confusion, muscle weakness, or seizures.

Alcol

It is best to avoid drinking alcohol while taking sertraline. Alcohol can increase the sedative effects of the medicine, making you feel more sleepy or unsteady on your feet. Additionally, alcohol can worsen the symptoms of depression or anxiety for which you are being treated.

Succo di pompelmo

Unlike some other medicines in their classes, apixaban and sertraline do not have a clinically significant interaction with grapefruit juice. You can consume it as normal.

Foods high in Vitamin K (e.g. leafy greens)

Unlike warfarin, apixaban is not affected by the amount of Vitamin K in your diet. You do not need to limit your intake of spinach, kale, or other leafy greens.

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Avvertenza

Queste informazioni sono solo a scopo educativo generale e non devono essere considerate un sostituto del consiglio medico professionale. Consultate sempre il vostro medico di base, farmacista o un altro professionista sanitario qualificato prima di prendere decisioni sui vostri farmaci. Le circostanze individuali possono variare, e solo un professionista sanitario che conosce la vostra storia medica può fornire una guida personalizzata.