Can I take Allopurinol and Mirtazapine together?

Perché succede

Allopurinol and mirtazapine are processed by different pathways in the body. Allopurinol works by blocking an enzyme called xanthine oxidase to lower uric acid levels, while mirtazapine affects chemical messengers in the brain. They do not interfere with each other's absorption, metabolism, or excretion.

You can take both medications as prescribed by your doctor. However, as with any combination of medicines, you should monitor for any new or unusual side effects and inform your healthcare provider if you feel unwell.

Severe skin reactions (SCARs)

Stop taking allopurinol immediately and seek urgent medical help if you develop a skin rash, peeling skin, or mouth ulcers. This can be a sign of a rare but life-threatening allergic reaction.

Agranulocytosis (low white blood cells)

Contact your doctor immediately if you develop signs of infection, such as a high temperature, sore throat, or mouth ulcers. Mirtazapine can rarely cause a serious drop in white blood cells.

Alcol

Alcohol can increase the sedative effects of mirtazapine, making you feel much sleepier and less alert. It is best to avoid drinking alcohol while taking this medicine, especially when you first start treatment or if your dose is increased.

Water/Hydration

It is important to drink plenty of fluids (at least 2 to 3 litres a day) while taking allopurinol. This helps to prevent the formation of kidney stones and ensures the medicine works correctly.

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Avvertenza

Queste informazioni sono solo a scopo educativo generale e non devono essere considerate un sostituto del consiglio medico professionale. Consultate sempre il vostro medico di base, farmacista o un altro professionista sanitario qualificato prima di prendere decisioni sui vostri farmaci. Le circostanze individuali possono variare, e solo un professionista sanitario che conosce la vostra storia medica può fornire una guida personalizzata.