tubulin beta 2B class IIb
Ultimo aggiornamento 4 maggio 2023
Rispetta le linee guida editoriali
- ScaricaScarica
- Condividi
- Language
- Discussione
- Versione audio
- Aggiungi alle fonti preferite su Google
L TUBB2B gene provides instructions for making one version of a protein called beta-tubulin (β-tubulin). This protein is part of the tubulin family of proteins that form and organize cell structures called microtubules. Microtubules are rigid, hollow fibers that make up the cell's structural framework (the cytoskeleton). They are composed of β-tubulin and a similar protein called alpha-tubulin (α-tubulin) that is produced from a different gene. Microtubules grow and shrink as tubulin proteins are added to and removed from the ends of fibers. This process allows cells to move and change shape.
Normal function
L TUBB2B gene provides instructions for making one version of a protein called beta-tubulin (β-tubulin). This protein is part of the tubulin family of proteins that form and organize cell structures called microtubules. Microtubules are rigid, hollow fibers that make up the cell's structural framework (the cytoskeleton). They are composed of β-tubulin and a similar protein called alpha-tubulin (α-tubulin) that is produced from a different gene. Microtubules grow and shrink as tubulin proteins are added to and removed from the ends of fibers. This process allows cells to move and change shape.
β-tubulin produced from the TUBB2B gene is found primarily in the brain and in nerve cells (neurons). In neurons, microtubules are integral for the cells' movement to the proper location in the brain and for a process called axon guidance, by which specialized extensions of neurons (axons) reach their correct positions. Once in the right location, axons relay messages to and from the brain to control muscle movement and detect sensations such as touch, pain, heat, and sound.
Conditions referring to this gene or chromosome
Altri nomi
class IIb beta-tubulin
TUBULIN, BETA, CLASS IIB
TUBULIN, BETA-2B
Related patient information and medicines
Patient information leaflet
Insufficienza cardiaca
If the symptoms have been going on for some time, it is called chronic heart failure. As a general rule, you will often be admitted to hospital if you have acute heart failure, whereas if you have chronic heart failure you will probably have tests done as an outpatient. If you have chronic heart failure, it is possible to develop acute heart.
Patient information leaflet
Posso prendere Atorvastatina e Bisoprololo insieme?
Perché succede Atorvastatin is a statin used to lower cholesterol, and bisoprolol è a beta-blocker used per manage blood pressure and heart rate. They are processed by different pathways in the body and do ... Our Controllo Interazioni Farmaci helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to.
Patient information leaflet
Posso assumere Shiitake e coda di volpe insieme?
Both are medicinal fungi that are... Why this happens Both mushrooms contain bioactive compounds called beta-glucans. These work in a similar way to support immune function without interfering with how the body processes the other. Avvertenza This information is per general educational purposes only and should not be relied upon as a substitute.
Patient information leaflet
Posso prendere Royal sun e White button insieme?
Both Royal Sun (Agaricus blazei) and White Button mushrooms contain compounds that may lower blood sugar levels. General Food Intake These medicinal mushrooms contain complex polysaccharides (beta-glucans). Nostro Controllo Interazioni Farmaci helps you check whether your prescriptions, over-the-counter medicines, e supplements are safe to take.
Patient information leaflet
Alfa-bloccanti
Alfa-bloccanti sono medicinali che sono principalmente utilizzati per treat high blood pressure (hypertension) e problemi con il passaggio dell'urina negli uomini che hanno un ingrossamento della ghiandola prostatica. L'ingrossamento della ghiandola prostatica è anche chiamato iperplasia prostatica benigna (IPB). A cosa servono gli alfa-bloccanti. In passato, alcuni alfa-bloccanti venivano anche usati per trattare.
Patient information leaflet
Posso prendere Royal sun e Turkey tail insieme?
Both Royal Sun (Agaricus blazei) and Turkey Tail (Trametes versicolor) are medicinal mushrooms that can stimulate the immune system. ...check whether your prescriptions, over-the-counter medicines, and supplements are safe to takeDisclaimer This information is for general educational purposes only and should not be relied upon as a substitute for.
Ulteriori letture e riferimenti
- tubulin beta 2B class IIb; MedlinePlus, National Library of Medicine.
- Cederquist GY, Luchniak A, Tischfield MA, Peeva M, Song Y, Menezes MP, Chan WM, Andrews C, Chew S, Jamieson RV, Gomes L, Flaherty M, Grant PE, Gupta ML Jr, Engle EC. An inherited TUBB2B mutation alters a kinesin-binding site and causes polymicrogyria, CFEOM and axon dysinnervation. Hum Mol Genet. 2012 Dec 15;21(26):5484-99. doi: 10.1093/hmg/dds393. Epub 2012 Sep 21.
- Di Donato N, Timms AE, Aldinger KA, Mirzaa GM, Bennett JT, Collins S, Olds C, Mei D, Chiari S, Carvill G, Myers CT, Riviere JB, Zaki MS; University of Washington Center for Mendelian Genomics; Gleeson JG, Rump A, Conti V, Parrini E, Ross ME, Ledbetter DH, Guerrini R, Dobyns WB. Analysis of 17 genes detects mutations in 81% of 811 patients with lissencephaly. Genet Med. 2018 Nov;20(11):1354-1364. doi: 10.1038/gim.2018.8. Epub 2018 Apr 19.
- Jaglin XH, Poirier K, Saillour Y, Buhler E, Tian G, Bahi-Buisson N, Fallet-Bianco C, Phan-Dinh-Tuy F, Kong XP, Bomont P, Castelnau-Ptakhine L, Odent S, Loget P, Kossorotoff M, Snoeck I, Plessis G, Parent P, Beldjord C, Cardoso C, Represa A, Flint J, Keays DA, Cowan NJ, Chelly J. Mutations in the beta-tubulin gene TUBB2B result in asymmetrical polymicrogyria. Nat Genet. 2009 Jun;41(6):746-52. doi: 10.1038/ng.380. Epub 2009 May 24.
- Romaniello R, Arrigoni F, Fry AE, Bassi MT, Rees MI, Borgatti R, Pilz DT, Cushion TD. Tubulin genes and malformations of cortical development. Eur J Med Genet. 2018 Dec;61(12):744-754. doi: 10.1016/j.ejmg.2018.07.012. Epub 2018 Jul 17.
- Romaniello R, Arrigoni F, Panzeri E, Poretti A, Micalizzi A, Citterio A, Bedeschi MF, Berardinelli A, Cusmai R, D'Arrigo S, Ferraris A, Hackenberg A, Kuechler A, Mancardi M, Nuovo S, Oehl-Jaschkowitz B, Rossi A, Signorini S, Tuttelmann F, Wahl D, Hehr U, Boltshauser E, Bassi MT, Valente EM, Borgatti R. Tubulin-related cerebellar dysplasia: definition of a distinct pattern of cerebellar malformation. Eur Radiol. 2017 Dec;27(12):5080-5092. doi: 10.1007/s00330-017-4945-2. Epub 2017 Jul 4.
Partecipa alla conversazione
Condividi i tuoi pensieri o esperienze con gli altri nel nostro comunità di pazienti.
Chiedi, condividi, connettiti.
Esplora le discussioni, fai domande e condividi esperienze su centinaia di argomenti di salute.
Iscriviti alla newsletter di Patient
La tua dose settimanale di consigli sulla salute chiari e affidabili - scritti per aiutarti a sentirti informato, sicuro e in controllo.
Abbonandoti accetti i nostri Informativa sulla Privacy. Puoi annullare l'iscrizione in qualsiasi momento. Non vendiamo mai i tuoi dati.