Posso prendere Sertralina e Citalopram insieme?

It is generally not recommended that you take sertralina e citalopram together as they are the same class of SSRI (antidepressivo) and work in the same way to increase serotonin levels.

Taking them together creates an 'additive effect' where the levels become dangerously high, increasing the risk of sindrome serotoninergica. Additionally, both drugs can affect the electrical activity of the heart in a similar way.

You should not take these two medicines together unless specifically instructed and closely monitored by a specialist.

Come sapere se stai avendo un'interazione farmacologica

You may be experiencing a drug interaction between sertraline and citalopram if you notice:

• Agitation, restlessness or confusion.

• Shivering or sweating.

• Muscle twitching, stiffness or jerking movements.

• Fast heartbeat.

• Diarrea.

• Mal di testa.

• Feeling unusually anxious or overactive.

These may be signs of sindrome serotoninergica, which can be serious.

Seek urgent medical help if you have:

• A high fever.

• Severe confusion or agitation.

• Convulsioni.

• Irregular heartbeat.

• Perdita di coscienza.

If you are currently taking both, do not stop taking them suddenly, but contact your doctor immediately to discuss a safe plan.

Disturbi depressivi e d'ansia

These medicines can cause an increase in suicidal thoughts or the urge to self-harm, particularly in the first few weeks of treatment or when the dose is changed. Monitor your mood closely.

Sindrome serotoninergica

Combining these with other medicines that affect serotonin (such as St John’s Wort, tramadol, or triptans) can cause a life-threatening reaction involving high fever, agitation, and muscle stiffness.

Disturbi emorragici

These medicines can increase your risk of bleeding, especially in the stomach. Use with caution if you take aspirin, ibuprofen (NSAIDs), or blood-thinning medicines like warfarin.

Disturbi del ritmo cardiaco (prolungamento del QT)

Citalopram can affect the electrical rhythm of your heart. It must be avoided if you have a pre-existing heart rhythm problem or are taking other medicines that affect the heart rate.

Bassi livelli di sodio (Iponatriemia)

Il citalopram può causare una diminuzione grave dei livelli di sodio nel sangue, soprattutto negli anziani. Rivolgiti a un medico se sperimenti stanchezza estrema, confusione o contrazioni muscolari.

Alcol

It is best to avoid or strictly limit alcohol while taking these medicines. Alcohol can increase the drowsiness and dizziness caused by the medication, and may also make your symptoms of depression or anxiety worse.

Succo di pompelmo

You should avoid drinking large amounts of grapefruit juice while taking sertraline. Grapefruit can increase the level of sertraline in your blood, which may increase the risk of side effects.

Caffeina (Caffè, Tè, Bevande Energetiche)

Il citalopram può talvolta causare sensazioni di irrequietezza o agitazione, soprattutto all'inizio del trattamento. La caffeina è uno stimolante che può peggiorare questi effetti collaterali e aumentare i sentimenti di ansia. È consigliabile monitorare l'assunzione di caffeina.

Taking multiple medicines? Our Controllo Interazioni Farmaci helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Avvertenza

Queste informazioni sono solo a scopo educativo generale e non devono essere considerate un sostituto del consiglio medico professionale. Consultate sempre il vostro medico di base, farmacista o un altro professionista sanitario qualificato prima di prendere decisioni sui vostri farmaci. Le circostanze individuali possono variare, e solo un professionista sanitario che conosce la vostra storia medica può fornire una guida personalizzata.