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Posso prendere Ibuprofene e Diclofenac insieme?

Guida alle interazioni farmacologiche

Taking ibuprofen and diclofenac together significantly increases your risk of serious side effects, particularly stomach ulcers, internal bleeding, and kidney problems. Because they both belong to the same family of medicines, taking them together is like taking a double dose of the same type of drug.

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Perché succede

Both ibuprofen and diclofenac are Non-Steroidal Anti-Inflammatory Drugs (NSAIDs). They work by blocking enzymes (COX-1 and COX-2) that produce chemicals called prostaglandins. While prostaglandins cause pain and inflammation, they also protect the lining of your stomach and keep your kidneys working properly. By blocking these enzymes twice over, you lose that vital protection, leading to a much higher risk of damage to your digestive system and kidneys.

Do not take these two medicines together. If you find that one is not providing enough pain relief, speak to your doctor or pharmacist. They may suggest a different type of painkiller that is safe to take alongside an NSAID, such as paracetamol. If you have already taken both and experience severe stomach pain, black tarry stools, or vomit that looks like coffee grounds, seek medical help immediately.

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Asma

Do not take these medicines if you have asthma and have ever experienced wheezing, breathlessness, or a skin rash after taking aspirin or other NSAIDs, as they can trigger a life-threatening asthma attack.

Ulcere gastriche o sanguinamento

Avoid these medicines if you have a history of stomach ulcers or gastrointestinal bleeding. They significantly increase the risk of serious stomach irritation and internal bleeding.

Gravidanza (Terzo Trimestre)

Do not take these medicines if you are more than 28 weeks pregnant. They can cause serious heart and kidney problems in the unborn baby and may lead to complications during delivery.

Alcol

Drinking alcohol while taking NSAIDs like diclofenac or ibuprofen can increase the risk of stomach irritation and bleeding. It is best to limit alcohol intake or avoid it entirely if you have a history of stomach issues.

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Taking multiple medicines? Our Controllo Interazioni Farmaci helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Avvertenza

Queste informazioni sono solo a scopo educativo generale e non devono essere considerate un sostituto del consiglio medico professionale. Consultate sempre il vostro medico di base, farmacista o un altro professionista sanitario qualificato prima di prendere decisioni sui vostri farmaci. Le circostanze individuali possono variare, e solo un professionista sanitario che conosce la vostra storia medica può fornire una guida personalizzata.

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Storia dell'articolo

Le informazioni su questa pagina sono scritte e revisionate da clinici qualificati.

  • 25 Gen 2026 | Pubblicato originariamente
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