Can I take Codeine and Paracetamol together?
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Pubblicato originariamente 25 Gen 2026
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Codeine and paracetamol are frequently used together to provide better pain relief than either medicine used alone. They do not have a negative interaction; instead, they work together in a helpful way. In fact, they are often sold combined in a single tablet (such as Co-codamol).
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It is generally considered safe to take codeina e paracetamolo together as these medicines work in different ways to stop pain.
Paracetamol works mainly in the central nervous system to reduce pain signals and lower fevers, while codeine is an opioid that changes how your brain and nervous system respond to pain.
Because they use different pathways, their effects are 'additive', meaning they provide a stronger combined effect.
How to take codeine and paracetamol together safely
Do not exceed the maximum dose for either medicine.
Check other cold or pain medicines to make sure they don’t already have paracetamol or codeine, as too much paracetamol can seriously damage your liver.
Precauzioni importanti
Torna ai contenutiLiver disease or heavy alcohol consumption
Taking paracetamol if you have liver problems or drink more than 14 units of alcohol per week significantly increases the risk of life-threatening liver damage, even at standard doses.
Asthma or breathing problems
Codeine can dangerously slow your breathing. You must not take it if you have severe asthma or chronic obstructive pulmonary disease (COPD), as it can lead to respiratory failure.
Opioid addiction or long-term use
Codeine is highly addictive. Using it for more than 3 days can lead to physical dependence and withdrawal symptoms; it should only be used for short-term pain relief.
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You must avoid drinking alcohol while taking codeine. Alcohol increases the sedative effects of codeine, which can lead to extreme sleepiness, breathing difficulties, and a higher risk of overdose.
Caffeina (caffè, tè, bevande energetiche)
Be cautious with caffeine if you are taking 'co-codamol' (a combination of codeine and paracetamol) that already contains caffeine. Too much caffeine can cause tremors, a racing heart, and difficulty sleeping. If your medicine does not already contain caffeine, normal intake is usually fine.
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Avvertenza
Queste informazioni sono solo a scopo educativo generale e non devono essere considerate un sostituto del consiglio medico professionale. Consultate sempre il vostro medico di base, farmacista o un altro professionista sanitario qualificato prima di prendere decisioni sui vostri farmaci. Le circostanze individuali possono variare, e solo un professionista sanitario che conosce la vostra storia medica può fornire una guida personalizzata.
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Storia dell'articolo
Le informazioni su questa pagina sono scritte e revisionate da clinici qualificati.
25 Gen 2026 | Pubblicato originariamente

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