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Can I take Propranolol and Ibuprofen together?

Guida alle interazioni farmacologiche

Taking ibuprofen can make propranolol less effective at lowering your blood pressure. Additionally, using these two medicines together can increase the risk of kidney problems, especially if you are older or have existing kidney issues.

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Perché succede

Propranolol works by blocking certain receptors to lower blood pressure. Ibuprofen belongs to a group of drugs (NSAIDs) that cause the body to retain salt and water and can narrow blood vessels in the kidneys. These actions directly oppose the blood-pressure-lowering effects of propranolol.

If you only need a single dose of ibuprofen, the risk is low. However, if you need regular pain relief, speak to your doctor or pharmacist. They may suggest an alternative like paracetamol. If you must take both, monitor your blood pressure regularly and watch for signs of fluid retention, such as swollen ankles.

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Asma o BPCO

You must not take propranolol if you have asthma or a history of wheezing. It can cause a life-threatening narrowing of the airways (bronchospasm).

Non assumere ibuprofene se hai l'asma, poiché può causare un peggioramento pericoloso della respirazione o una grave reazione allergica.

Stomach ulcers or gastritis

Do not take ibuprofen if you have ever had a stomach ulcer, perforation, or bleeding. It significantly increases the risk of serious internal bleeding.

Gravidanza (terzo trimestre)

Do not take ibuprofen if you are more than 28 weeks pregnant. It can cause serious heart and kidney problems in the unborn baby and complications during birth.

Diabete

Propranolol can hide the early warning signs of low blood sugar (hypoglycaemia), such as a fast heartbeat or tremors. You will need to monitor your blood sugar more closely.

Stopping treatment

Do not stop taking propranolol suddenly. Doing so can cause a dangerous rebound increase in blood pressure or worsen heart conditions. Your dose must be reduced gradually by a doctor.

Alcol

Drinking alcohol while taking propranolol can increase the medicine's blood-pressure-lowering effect, which may make you feel dizzy or lightheaded. It is best to limit or avoid alcohol, especially when you first start treatment or if your dose is increased.

It is best to avoid or strictly limit alcohol while taking ibuprofen. Combining alcohol with non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen increases the risk of irritation to your stomach lining and can lead to stomach ulcers or bleeding.

Caffeina

Propranolol is often used to treat physical symptoms of anxiety or heart palpitations. Caffeine (found in coffee, tea, and energy drinks) is a stimulant that can increase your heart rate and blood pressure, potentially working against the effects of your medicine.

Cibo (Generale)

Propranolol can be taken with or without food, but you should be consistent. Taking it with food can increase the amount of medicine absorbed by your body. It is best to always take it the same way (either always with food or always without) to keep your blood levels steady.

Si consiglia di assumere l'ibuprofene con il cibo o un bicchiere di latte per ridurre il rischio di mal di stomaco o indigestione.

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Taking multiple medicines? Our Controllo Interazioni Farmaci helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Avvertenza

Queste informazioni sono solo a scopo educativo generale e non devono essere considerate un sostituto del consiglio medico professionale. Consultate sempre il vostro medico di base, farmacista o un altro professionista sanitario qualificato prima di prendere decisioni sui vostri farmaci. Le circostanze individuali possono variare, e solo un professionista sanitario che conosce la vostra storia medica può fornire una guida personalizzata.

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Storia dell'articolo

Le informazioni su questa pagina sono scritte e revisionate da clinici qualificati.

  • 24 Gen 2026 | Pubblicato originariamente
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